2. Antibody-drug Conjugate/ADC Related
  3. ADC Linker
  4. MC-Gly-Gly-{D-Phe}-Gly-NH-CH2-O-CH2COOH

MC-Gly-Gly-{D-Phe}-Gly-NH-CH2-O-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

For research use only. We do not sell to patients.

MC-Gly-Gly-{D-Phe}-Gly-NH-CH2-O-CH2COOH Chemical Structure

MC-Gly-Gly-{D-Phe}-Gly-NH-CH2-O-CH2COOH Chemical Structure

CAS No. : 1802520-40-6

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MC-Gly-Gly-{D-Phe}-Gly-NH-CH2-O-CH2COOH Related Antibodies

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Description

MC-Gly-Gly-{D-Phe}-Gly-NH-CH2-O-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

In Vitro

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

MC-Gly-Gly-{D-Phe}-Gly-NH-CH2-O-CH2COOH Related Antibodies
Molecular Weight

616.62

Formula

C28H36N6O10
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

OC(COCNC(CNC([C@H](NC(CNC(CNC(CCCCCN1C(C=CC1=O)=O)=O)=O)=O)CC2=CC=CC=C2)=O)=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Purity & Documentation
References
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MC-Gly-Gly-{D-Phe}-Gly-NH-CH2-O-CH2COOH Related Classifications

  • Molarity Calculator

  • Dilution Calculator

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

MC-Gly-Gly-{D-Phe}-Gly-NH-CH2-O-CH2COOH1802520-40-6ADC LinkerAntibody-drug conjugates linkerADCcleavablelinkerInhibitorinhibitorinhibit

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MC-Gly-Gly-{D-Phe}-Gly-NH-CH2-O-CH2COOH
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