2. Others Metabolic Enzyme/Protease NF-κB Anti-infection Immunology/Inflammation Vitamin D Related/Nuclear Receptor
  3. Reference Standards Drug Metabolite FXR Keap1-Nrf2 Heme Oxygenase (HO) Dengue Virus Bacterial Reactive Oxygen Species (ROS) Estrogen Receptor/ERR Cytochrome P450
  4. (-)-(E)-Guggulsterone (Standard)

(-)-(E)-Guggulsterone (Standard)  (Synonyms: (E)-Guggulsterone (Standard))

Cat. No.: HY-N7781R Purity: 98%
Handling Instructions Technical Support

(-)-(E) -guggulsterone (Standard) is the analytical standard for (-)-(E) -guggulsterone ((E)-Guggulsterone) (HY-N7781). (-)-(E)-Guggulsterone is an orally active natural stereoisomer of Guggulsterone (HY-107738). (-)-(E)-Guggulsterone is an antagonist for the Farnesoid X Receptor (FXR) with an IC50 of 24.06 μM and possesses potent hypolipidemic properties. (-)-(E)-Guggulsterone suppresses dengue virus (DENV) replication by upregulating antiviral interferon responses by inducing HO-1 expression via Nrf2 activation. (-)-(E)-Guggulsterone exhibits antibacterial activities against Bacillus subtilis, Staphylococcus aureus and Pseudomonas aeruginosa. (-)-(E)-Guggulsterone has cardiac protective and antioxidant activities in rats.

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(-)-(E)-Guggulsterone (Standard)

(-)-(E)-Guggulsterone (Standard) 화학구조

CAS No. : 39025-24-6

사이즈 가격 재고 수량
5 mg 견적 받기 4 - 6 Weeks 3 - 5 Weeks 5 - 7 Weeks 4 - 6 weeks
10 mg 견적 받기 4 - 6 Weeks 3 - 5 Weeks 5 - 7 Weeks 4 - 6 weeks
25 mg 견적 받기 4 - 6 Weeks 3 - 5 Weeks 5 - 7 Weeks 4 - 6 weeks
50 mg 견적 받기 4 - 6 Weeks 3 - 5 Weeks 5 - 7 Weeks 4 - 6 weeks
100 mg 견적 받기 4 - 6 Weeks 3 - 5 Weeks 5 - 7 Weeks 4 - 6 weeks
200 mg   견적 받기  
500 mg   견적 받기  
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Information

(-)-(E) -guggulsterone (Standard) is the analytical standard for (-)-(E) -guggulsterone ((E)-Guggulsterone) (HY-N7781). (-)-(E)-Guggulsterone is an orally active natural stereoisomer of Guggulsterone (HY-107738). (-)-(E)-Guggulsterone is an antagonist for the Farnesoid X Receptor (FXR) with an IC50 of 24.06 μM and possesses potent hypolipidemic properties. (-)-(E)-Guggulsterone suppresses dengue virus (DENV) replication by upregulating antiviral interferon responses by inducing HO-1 expression via Nrf2 activation. (-)-(E)-Guggulsterone exhibits antibacterial activities against Bacillus subtilis, Staphylococcus aureus and Pseudomonas aeruginosa. (-)-(E)-Guggulsterone has cardiac protective and antioxidant activities in rats.

Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
분자량

312.45

화학식

C21H28O2
CAS No.
SMILES

C/C=C1C(C[C@@]2([H])[C@]3([H])CCC4=CC(CC[C@]4(C)[C@@]3([H])CC[C@]/12C)=O)=O
Structure Classification
Initial Source
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.
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(-)-(E)-Guggulsterone (Standard) Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(-)-(E)-Guggulsterone (Standard)39025-24-6(E)-Guggulsterone (Standard)Reference StandardsDrug MetaboliteFXRKeap1-Nrf2Heme Oxygenase (HO)Dengue VirusBacterialReactive Oxygen Species (ROS)Estrogen Receptor/ERRCytochrome P450NR1H4Heme OxygenaseDENVCYPsInhibitorinhibitorinhibit

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상품명:
(-)-(E)-Guggulsterone (Standard)
Cat. No.:
HY-N7781R
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