Misoprostol acid

Name: Misoprostol acid
Brand: MedChemExpress
SKU: HY-118189
Rating: 4.5 (1 reviews)

Cat. No.: HY-118189 Pureza: 99.9%: Ficha de datos
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Misoprostol acid is an active metabolite of Misoprostol. Misoprostol is a synthetic analogue of prostaglandin E1 (PGE1), extensively absorbed, and undergoes rapid de-esterification to Misoprostol acid in the gastrointestinal tract after oral administration. Misoprostol can be used for non-steroidal anti-inflammatory drug-induced (NSAID) gastric ulcers. Misoprostol is an oral agent used to induce labor.

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Misoprostol acid Estructura química

No. CAS : 112137-89-0

Tamaño	Precio	Stock	Cantidad
Solvent
1 mg (27.14 mM * 100 μL in Methyl acetate)		En stock	Estimated Time of Arrival: December 31

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Revisión del cliente

Based on 1 publication(s) in Google Scholar

Other Forms of Misoprostol acid:

Misoprostol acid-d₅ Obtener un presupuesto

1 Publications Citing Use of MCE Misoprostol acid

•J Interferon Cytokine Res. 2025 Dec 2. [Abstract]

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Descripciòn

Misoprostol acid is an active metabolite of Misoprostol. Misoprostol is a synthetic analogue of prostaglandin E1 (PGE1), extensively absorbed, and undergoes rapid de-esterification to Misoprostol acid in the gastrointestinal tract after oral administration. Misoprostol can be used for non-steroidal anti-inflammatory drug-induced (NSAID) gastric ulcers^[1]. Misoprostol is an oral agent used to induce labor^[2].

IC₅₀ & Target

In Vivo

Unlike the Misoprostol, Misoprostol acid is detectable in plasma. Misoprostol is a lipophilic methyl ester prodrug and is readily metabolized to the free acid, which is the biologically active form. Misoprostol is used worldwide for a variety of indications in obstetrics and gynecology. Misoprostol has both gastric antisecretory and mucosal protective effects^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Peso molecular

368.51

Fòrmula

C₂₁H₃₆O₅

No. CAS

112137-89-0

Appearance

Liquid

Color

Colorless to light yellow

SMILES

O[C@H]1[C@@H]([C@H](C(C1)=O)CCCCCCC(O)=O)/C=C/CC(O)(CCCC)C

Envío

Room temperature in continental US; may vary elsewhere.

Almacenamiento

Solution, -20°C, 2 years

Pureza y Documentación

Purity: 99.9%

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Ficha de datos (274 KB) SDS (645 KB)

COA (252 KB)

Instrucciones de manejo (2659 KB)

Referencias

[1]. Vijaya Bharathi D, et al. Development and validation of highly sensitive method for determination of misoprostol free acid in human plasma by liquid chromatography-electrospray ionization tandem mass spectrometry: application to a clinical pharmacokinetic study. J Chromatogr B Analyt Technol Biomed Life Sci. 2011 Sep 15;879(26):2827-33. [Content Brief]

[2]. Schmidt-Hansen M, et al. Simultaneous compared to interval administration of mifepristone and misoprostol for medical abortion up to 10+0 weeks' gestation: a systematic review with meta-analyses. BMJ Sex Reprod Health. 2020 Feb 20. pii: bmjsrh-2019-200448. [Content Brief]