2. Antibody-drug Conjugate/ADC Related Protein Tyrosine Kinase/RTK JAK/STAT Signaling
  3. EGFR Antibody-Drug Conjugates (ADCs)
  4. Becotatug vedotin

Becotatug vedotin (MRG003) is an Antibody-Drug Conjugate (ADC) that consists of an anti-EGFR humanized IgG1 monoclonal antibody Becotatug (HY-P990049) and MMAE (HY-15162). These two parts are connected through a valine-citrulline (valine-citrulline) linker, where the linker and MMAE constitute the ADC's Drug-Linker conjugate VcMMAE (HY-15575).

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Becotatug vedotin

Becotatug vedotin Estructura química

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Becotatug vedotin Related Antibodies

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Descripciòn

Becotatug vedotin (MRG003) is an Antibody-Drug Conjugate (ADC) that consists of an anti-EGFR humanized IgG1 monoclonal antibody Becotatug (HY-P990049) and MMAE (HY-15162). These two parts are connected through a valine-citrulline (valine-citrulline) linker, where the linker and MMAE constitute the ADC's Drug-Linker conjugate VcMMAE (HY-15575)[1].

Ensayo clínico
Peso molecular

149470 (average)

Appearance

Liquid

Color

Colorless to light yellow

SMILES

[Becotatug vedotin]
Envío

Shipping with dry ice.
Almacenamiento

-80°C, protect from light
Pureza y Documentación
Referencias
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Becotatug vedotin Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Becotatug vedotinMRG003MRG 003MRG-003EGFRAntibody-Drug Conjugates (ADCs)Epidermal growth factor receptorErbB-1HER1Antibody-Drug ConjugatesInhibitorinhibitorinhibit

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Nombre del producto:
Becotatug vedotin
Cat. No.:
HY-171265
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