2. Antibody-drug Conjugate/ADC Related Protein Tyrosine Kinase/RTK JAK/STAT Signaling
  3. EGFR Antibody-Drug Conjugates (ADCs)
  4. Becotatug vedotin

Becotatug vedotin  (Synonyms: MRG003)

Art. -Nr.: HY-171265 Reinheit: 96.99%
COA
SDS
Handling Instructions Technical Support

Becotatug vedotin (MRG003) is an Antibody-Drug Conjugate (ADC) that consists of an anti-EGFR humanized IgG1 monoclonal antibody Becotatug (HY-P990049) and MMAE (HY-15162). These two parts are connected through a valine-citrulline (valine-citrulline) linker, where the linker and MMAE constitute the ADC's Drug-Linker conjugate VcMMAE (HY-15575).

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Becotatug vedotin

Becotatug vedotin Chemische Struktur

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Becotatug vedotin Related Antibodies

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EGFR/ErbB1/HER1 ErbB2/HER2 ErbB3/HER3 ErbB4/HER4

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Beschreibung

Becotatug vedotin (MRG003) is an Antibody-Drug Conjugate (ADC) that consists of an anti-EGFR humanized IgG1 monoclonal antibody Becotatug (HY-P990049) and MMAE (HY-15162). These two parts are connected through a valine-citrulline (valine-citrulline) linker, where the linker and MMAE constitute the ADC's Drug-Linker conjugate VcMMAE (HY-15575)[1].

Klinische Studie
Molekulargewicht

149470 (average)

Appearance

Liquid

Color

Colorless to light yellow

SMILES

[Becotatug vedotin]
Versand

Shipping with dry ice.
Speicherung

-80°C, protect from light
Reinheit & Dokumentation

Purity: 96.99%

SDS (251 KB)

COA (231 KB) Others (216 KB) SEC-HPLC (67 KB)

Handling Instructions (2659 KB)
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Becotatug vedotin Related Classifications

  • Molaritätsrechner

  • Verdünnungsrechner

Die Formel zur Berechnung von Molaritäten

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)

Diese Gleichung wird häufig abgekürzt als: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Becotatug vedotinMRG003MRG 003MRG-003EGFRAntibody-Drug Conjugates (ADCs)Epidermal growth factor receptorErbB-1HER1Antibody-Drug ConjugatesInhibitorinhibitorinhibit

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SAFETY DATA SHEET (SDS)

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