2. Anti-infection
  3. Bacterial
  4. Naphthomycin A

Naphthomycin A has the effect of anti Gram-positive bacteria and fungi, and inhibits the synthesis of fatty acids by coliform bacteria.

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Naphthomycin A

Naphthomycin A Chemical Structure

CAS No. : 55557-40-9

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Naphthomycin A Related Antibodies

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Description

Naphthomycin A has the effect of anti Gram-positive bacteria and fungi, and inhibits the synthesis of fatty acids by coliform bacteria[1].

Cellular Effect
Cell Line Type Value Description References
A549 IC50
15.91 μM
Compound: 4
Growth inhibition of human A549 cells by MTT assay
Growth inhibition of human A549 cells by MTT assay
[PMID: 22742732]
HL-60 IC50
2.1 μM
Compound: 7
Antiproliferative activity against human HL60 cells after 48 hrs by EZ-Cytox cell viability assay
Antiproliferative activity against human HL60 cells after 48 hrs by EZ-Cytox cell viability assay
[PMID: 28406643]
HL-60 IC50
25.61 μM
Compound: 4
Growth inhibition of human HL60 cells by MTT assay
Growth inhibition of human HL60 cells by MTT assay
[PMID: 22742732]
HeLa IC50
30.2 μM
Compound: 7
Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay
Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay
[PMID: 28406643]
MCF7 IC50
11.67 μM
Compound: 4
Growth inhibition of human MCF7 cells by MTT assay
Growth inhibition of human MCF7 cells by MTT assay
[PMID: 22742732]
MDA-MB-231 IC50
34.6 μM
Compound: 7
Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by MTT assay
Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by MTT assay
[PMID: 28406643]
SMMC-7721 IC50
16.62 μM
Compound: 4
Growth inhibition of human SMMC7721 cells by MTT assay
Growth inhibition of human SMMC7721 cells by MTT assay
[PMID: 22742732]
SW480 IC50
11.66 μM
Compound: 4
Growth inhibition of human SW480 cells by MTT assay
Growth inhibition of human SW480 cells by MTT assay
[PMID: 22742732]
SW480 IC50
7.6 μM
Compound: 7
Antiproliferative activity against human SW480 cells after 48 hrs by MTT assay
Antiproliferative activity against human SW480 cells after 48 hrs by MTT assay
[PMID: 28406643]
U2OS IC50
20.5 μM
Compound: 7
Antiproliferative activity against human U2OS cells after 48 hrs by MTT assay
Antiproliferative activity against human U2OS cells after 48 hrs by MTT assay
[PMID: 28406643]
Molecular Weight

720.25

Formula

C40H46ClNO9
CAS No.
SMILES

C/C(C(NC1=C(C(C2=C3C(O)=C(C=C2C1=O)C)=O)Cl)=O)=C/C=C\C=C\[C@@H]([C@H](CC(/C(C)=C/C[C@@H](/C=C/[C@@H]([C@@H]([C@H](/C=C(C3=O)\C)C)O)C)O)=O)O)C
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Naphthomycin A Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Naphthomycin A55557-40-9BacterialInhibitorinhibitorinhibit

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