2. Membrane Transporter/Ion Channel
  3. Sodium Channel
  4. Nifedipine hydrochloride

Nifedipine hydrochloride is a potent vasodilator with calcium antagonist activity. Nifedipine hydrochloride is a useful antianginal compound that can also lower blood pressure. Nifedipine hydrochloride exhibits comparable antihypertensive properties to some new compounds, especially in calcium channel blockade. Nifedipine hydrochloride is used in biological activity studies to develop new antihypertensive and/or antianginal compounds.

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CAS. Nr. : 60299-11-8

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Nifedipine hydrochloride Related Antibodies

Top Publications Citing Use of Products

28 Publications Citing Use of MCE Nifedipine hydrochloride

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Bio/Physico-chemical Assay

    Nifedipine hydrochloride purchased from MedChemExpress. Usage Cited in: Alzheimers Res Ther. 2025 Dec 1;17(1):253.  [Abstract]

    Nifedipine (5 µM, 1 min) decreased the neuronal cytoplasmic Ca2+ levels induced by 20 µM glutamate.

    Nifedipine hydrochloride purchased from MedChemExpress. Usage Cited in: Pharmaceuticals (Basel). 2025 Sep 21;18(9):1420.  [Abstract]

    Nifedipine (0.01 µM, 30 min) inhibited contractions induced by Ca2+ influx, keeping the contraction force below 0.1 g even at the highest calcium concentration of 10 mM.

    Nifedipine hydrochloride purchased from MedChemExpress. Usage Cited in: Sci Signal. 2020 Nov 24;13(659):eaax0273.  [Abstract]

    Nifedipine (10 µM, 30 min) relaxed 0.3 μM ACh-constricted mouse airways.

    Nifedipine hydrochloride purchased from MedChemExpress. Usage Cited in: Sci Signal. 2020 Nov 24;13(659):eaax0273.  [Abstract]

    Pretreatment with nifedipine (10 µM, 30 min) reduced ACh-induced airway constriction by about 25% but did not affect osthole-induced relaxation in mouse airways.

    Nifedipine hydrochloride purchased from MedChemExpress. Usage Cited in: Front Endocrinol. 2018 Nov 30:9:721.  [Abstract]

    Nifedipine (4 µM, 4 h) abolished the stimulation of Gh release by GnRH1 or GnRH3 in primary cultured pituitary cells from mixed-sex rice field eels.

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    Beschreibung

    Nifedipine hydrochloride is a potent vasodilator with calcium antagonist activity. Nifedipine hydrochloride is a useful antianginal compound that can also lower blood pressure. Nifedipine hydrochloride exhibits comparable antihypertensive properties to some new compounds, especially in calcium channel blockade. Nifedipine hydrochloride is used in biological activity studies to develop new antihypertensive and/or antianginal compounds[1].

    Molekulargewicht

    382.80

    Formel

    C17H19ClN2O6
    CAS. Nr.
    SMILES

    O=C(C1=C(C)NC(C)=C(C(OC)=O)C1C2=CC=CC=C2[N+]([O-])=O)OC.Cl
    Versand

    Room temperature in continental US; may vary elsewhere.
    Speicherung

    Please store the product under the recommended conditions in the Certificate of Analysis.
    Reinheit & Dokumentation
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    Nifedipine hydrochloride Related Classifications

    • Molaritätsrechner

    • Verdünnungsrechner

    Die Formel zur Berechnung von Molaritäten

    Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

    Mass   Concentration   Volume   Molecular Weight *
    = × ×

    The dilution calculator equation

    Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)

    Diese Gleichung wird häufig abgekürzt als: C1V1 = C2V2

    Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
    × = ×
    C1   V1   C2   V2
    Help & FAQs
    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

    Keywords:

    Nifedipine60299-11-8Sodium ChannelNa channelsNa+ channelsInhibitorinhibitorinhibit

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