NR2F2-IN-1 free base

製品番号: HY-156190A 純度: 99.31%: Data Sheet SDS COA 取扱説明書
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NR2F2-IN-1 (free base) is a potent and selective orphan nuclear receptor COUP-TFII (NR2F2) inhibitor. NR2F2-IN-1 (free base) substantially inhibits COUP-TFII–driven NGFIA reporter expression. NR2F2-IN-1 (free base) directly binds to the COUP-TFII ligand-binding domain and disrupts COUP-TFII interaction with transcription regulators, including FOXA1, thus repressing COUP-TFII activity on target gene regulation.

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研究用途以外に使用した場合、当社は一切の責任を負いかねます。

NR2F2-IN-1 free base 構造式

CAS 番号 : 452087-38-6

容量	価格（税別）	在庫状況	数量
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	USD 165	在庫あり	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	USD 165	在庫あり	Estimated Time of Arrival: December 31
Solid
5 mg	$150	在庫あり	Estimated Time of Arrival: December 31
10 mg	$240	在庫あり	Estimated Time of Arrival: December 31
25 mg	$480	在庫あり	Estimated Time of Arrival: December 31
50 mg	$750	在庫あり	Estimated Time of Arrival: December 31
100 mg	$1150	在庫あり	Estimated Time of Arrival: December 31
200 mg		お問い合わせ
500 mg		お問い合わせ

or バルクお問い合わせ

* アイテムを追加する前、数量をご選択ください

This product is a controlled substance and not for sale in your territory.

カスタマーレビュー

Based on 0 publication(s) in Google Scholar

Other Forms of NR2F2-IN-1 free base:

NR2F2-IN-1 お問い合わせ

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製品説明

分子量

329.42

分子式

C₁₇H₁₉N₃O₂S

CAS 番号

452087-38-6

Appearance

Solid

Color

Light yellow to yellow

SMILES

COC(C(OC)=C1)=CC=C1CCNC2=C3C=C(C)SC3=NC=N2

輸送条件

Room temperature in continental US; may vary elsewhere.

保管条件

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

溶剤 & 溶解度

体外:

DMSO : 125 mg/mL (379.45 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.0356 mL	15.1782 mL	30.3564 mL
5 mM	0.6071 mL	3.0356 mL	6.0713 mL
10 mM	0.3036 mL	1.5178 mL	3.0356 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

一般には略語で表示されます：C₁V₁ = C₂V₂

濃度 _（開始）

体積 _（開始）

濃度 _（終了）

体積 _（終了）

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

純度とドキュメンテーション

純度: 99.31%

Select Batch:

データシート (272 KB) SDS (251 KB)

COA (250 KB) HNMR (256 KB) RP-HPLC (249 KB) MS (229 KB)

取扱説明書 (2659 KB)

参考文献

[1]. Leiming Wang, et al. Small-molecule inhibitor targeting orphan nuclear receptor COUP-TFII for prostate cancer treatment. Sci Adv. 2020 Apr 29;6(18):eaaz8031. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	3.0356 mL	15.1782 mL	30.3564 mL	75.8910 mL
	5 mM	0.6071 mL	3.0356 mL	6.0713 mL	15.1782 mL
	10 mM	0.3036 mL	1.5178 mL	3.0356 mL	7.5891 mL
	15 mM	0.2024 mL	1.0119 mL	2.0238 mL	5.0594 mL
	20 mM	0.1518 mL	0.7589 mL	1.5178 mL	3.7945 mL
	25 mM	0.1214 mL	0.6071 mL	1.2143 mL	3.0356 mL
	30 mM	0.1012 mL	0.5059 mL	1.0119 mL	2.5297 mL
	40 mM	0.0759 mL	0.3795 mL	0.7589 mL	1.8973 mL
	50 mM	0.0607 mL	0.3036 mL	0.6071 mL	1.5178 mL
	60 mM	0.0506 mL	0.2530 mL	0.5059 mL	1.2648 mL
	80 mM	0.0379 mL	0.1897 mL	0.3795 mL	0.9486 mL
	100 mM	0.0304 mL	0.1518 mL	0.3036 mL	0.7589 mL