452087-38-6
Chemical Structure
NR2F2-IN-1 free base
- CAS No.: 452087-38-6
- Formula:C17H19N3O2S
- Molecular Weight:329.42
InChIKey: CRLNCEZRMMLCIH-UHFFFAOYSA-N
SMILES: COC(C(OC)=C1)=CC=C1CCNC2=C3C=C(C)SC3=NC=N2
Biological Activity: NR2F2-IN-1 (COUP-TFII inhibitor) free base is a small-molecule inhibitor targeting the orphan nuclear receptor COUP-TFII (NR2F2). NR2F2-IN-1 free base directly binds to the ligand-binding domain of COUP-TFII (NR2F2) and disrupts its interaction with transcriptional regulators including FOXA1. NR2F2-IN-1 free base induces anti-tumor activity in prostate cancer and can be used for prostate cancer research[1].
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NR2F2-IN-1 free base | 99.31% | NR2F2-IN-1 (COUP-TFII inhibitor) free base is a small-molecule inhibitor targeting the orphan nuclear receptor COUP-TFII (NR2F2). NR2F2-IN-1 free base directly binds to the ligand-binding domain of COUP-TFII (NR2F2) and disrupts its interaction with transcriptional regulators including FOXA1. NR2F2-IN-1 free base induces anti-tumor activity in prostate cancer and can be used for prostate cancer research. | ||||||||||||||||||||
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Keywords