2. Anti-infection
  3. Bacterial
  4. Omiganan

Omiganan is a cationic antimicrobial peptide. Omiganan as an analogue of indolicidin shows activity against gram-positive and gram-negative bacteria but also Candida spp. isolates. Omiganan can be used for the research of alcohol nose and acne.

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Synthèse de peptides personnalisée

Omiganan

Omiganan Chemical Structure

CAS No. : 204248-78-2

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10 mg En stock
25 mg En stock
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Based on 2 publication(s) in Google Scholar

Other Forms of Omiganan:

Omiganan Related Antibodies

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Description

Omiganan is a cationic antimicrobial peptide. Omiganan as an analogue of indolicidin shows activity against gram-positive and gram-negative bacteria but also Candida spp. isolates. Omiganan can be used for the research of alcohol nose and acne[1][2].

In Vivo

Omiganan results in a statistically significantly reduction in bacterial counts. omiganan reduces the bacterial counts by 3.8 (S. aureus), 2.2 (S. epidermidis) and 2.3 (C. albicans) log10 CFU/site. Omiganan has rapid bactericidal and fungicidal properties and significant dose-dependent activity against a broad spectrum of infected organisms[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Masse moléculaire

1779.15

Formule

C90H127N27O12
CAS No.
Appearance

Solid

Color

Off-white to light yellow

Sequence Shortening

ILRWPWWPWRRK-NH2
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Sealed storage, away from moisture and light, under nitrogen

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)

Solvant et solubilité
In Vitro: 

H2O : 50 mg/mL (28.10 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.5621 mL 2.8103 mL 5.6207 mL
5 mM 0.1124 mL 0.5621 mL 1.1241 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Calculateur de molarité

  • Calculateur de dilution

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Pureté et documentation
Références

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 0.5621 mL 2.8103 mL 5.6207 mL 14.0517 mL
5 mM 0.1124 mL 0.5621 mL 1.1241 mL 2.8103 mL
10 mM 0.0562 mL 0.2810 mL 0.5621 mL 1.4052 mL
15 mM 0.0375 mL 0.1874 mL 0.3747 mL 0.9368 mL
20 mM 0.0281 mL 0.1405 mL 0.2810 mL 0.7026 mL
25 mM 0.0225 mL 0.1124 mL 0.2248 mL 0.5621 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Omiganan Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Omiganan204248-78-2Bacterialcationicantimicrobialpeptideindolicidingram-positivegram-negativebacteriaInhibitorinhibitorinhibit

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