2. Anticuerpos inhibidores
  3. Biosimilar Antibodies
  4. Monoclonal Antibodies
  5. Pateclizumab

Pateclizumab  (Synonyms: MLTA3698A; RG7415; PRO283698)

Cat. No.: HY-P990034 Pureza: ≥99.0%
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Pateclizumab (MLTA3698A) is a humanized antibody against lymphotoxin α (LTα), a transiently expressed cytokine on activated B and T cells (Th1, Th17), which are implicated in rheumatoid arthritis (RA) pathogenesis.

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No. CAS : 1202526-59-7

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Revisión del cliente

Based on 1 publication(s) in Google Scholar

Pateclizumab Recomendaciones destacadas:

Pateclizumab Related Antibodies

Top Publications Citing Use of Products

1 Publications Citing Use of MCE Pateclizumab

  • Actividad biológica

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  • Referencias

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Descripciòn

Pateclizumab (MLTA3698A) is a humanized antibody against lymphotoxin α (LTα), a transiently expressed cytokine on activated B and T cells (Th1, Th17), which are implicated in rheumatoid arthritis (RA) pathogenesis[1].

Isotype

Human IgG1 kappa
Recommend Isotype Controls
Species Reactivity

Human
IC50 & Target

TNFSF1/TNFb/LT alpha
Ensayo clínico
Gene ID

4049  [NCBI]

Accession
Application

ELISA, FACS, Functional assay
Conjugated

Unconjugated
Reconsititution

The product can be reconstituted/diluted with sterile PBS or saline.
Peso molecular

144.9 kDa

No. CAS
Appearance

Liquid

Color

Colorless to light yellow

SMILES

[Pateclizumab]
Envío

Shipping with dry ice.
Formulation

Please refer to the lot-specific COA for specific buffer information.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.
Format
  • Human IgG1 kappa
Biological Activity
  • Immobilized TNF-beta/TNFSF1 Protein, Human (HY-P7304) can bind Pateclizumab. The EC50 for this effect is 1.799 ng/mL.
Pureza y Documentación
Referencias
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Pateclizumab Related Classifications

  • Calculadora de molaridad

  • Calculadora de dilución

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Pateclizumab1202526-59-7MLTA3698A RG7415 PRO283698RG7415RG 7415RG-7415PRO283698PRO 283698PRO-283698Otherslymphotoxin αLTαTh1Th17rheumatoid arthritisRAInhibitorinhibitorinhibit

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Inquiry Information

Nombre del producto:
Pateclizumab
Cat. No.:
HY-P990034
Cantidad:
MCE Japan Authorized Agent:

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