Phenylglyoxylic acid-d₅ sodium (Synonyms: Benzoylformic acid-d5sodium; Sodium phenylglyoxylate-d5)

Cat. No.: HY-W010255AS Pureza: 99.79%: Ficha de datos
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Phenylglyoxylic acid-d₅ (Benzoylformic acid-d₅) sodium is the deuterium labeled Phenylglyoxylic acid sodium (HY-W010255A). Phenylglyoxylic acid (Benzoylformic acid) is a metabolite of ethylbenzene and styrene (EB/S) and can be used as a biomarker of exposure to EB/S in human. Phenylglyoxylic acid can be used as drug intermediate for synthesis of antineoplastic compounds.

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Phenylglyoxylic acid-d<sub>5</sub> sodium

Phenylglyoxylic acid-d₅ sodium Estructura química

No. CAS : 2708283-39-8

Tamaño	Stock	Cantidad
5 mg	En stock	Estimated Time of Arrival: December 31
10 mg	En stock	Estimated Time of Arrival: December 31
25 mg	Obtener un presupuesto 2-4 weeks 2-4 weeks 2-4 weeks 2-4 weeks	Estimated Time of Arrival: December 31
50 mg	Obtener un presupuesto 2-4 weeks 2-4 weeks 2-4 weeks 2-4 weeks	Estimated Time of Arrival: December 31
100 mg	Obtener un presupuesto
200 mg	Obtener un presupuesto

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Other Forms of Phenylglyoxylic acid-d₅ sodium:

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Human Endogenous Metabolite Microbial Metabolite

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Descripciòn

Application

1. This compound can be used as a tracer.
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Peso molecular

178.15

Fòrmula

C₈HD₅NaO₃

No. CAS

2708283-39-8

Unlabeled CAS

43165-51-1

Appearance

Solid

Color

White to off-white

SMILES

OC(C(C1=C([2H])C([2H])=C([2H])C([2H])=C1[2H])=O)=O.[Na]

Envío

Room temperature in continental US; may vary elsewhere.

Almacenamiento

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvente y solubilidad

In Vitro:

H₂O : ≥ 100 mg/mL (561.32 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	5.6132 mL	28.0662 mL	56.1325 mL
5 mM	1.1226 mL	5.6132 mL	11.2265 mL
10 mM	0.5613 mL	2.8066 mL	5.6132 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Calculadora de molaridad
Calculadora de dilución

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

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Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Pureza y Documentación

Purity: 99.79%

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Ficha de datos (274 KB) SDS (252 KB)

COA (250 KB) HNMR (650 KB) RP-HPLC (809 KB)

Instrucciones de manejo (2659 KB)

Referencias

[1]. Capella KM, et al. Ethylbenzene and styrene exposure in the United States based on urinary mandelic acid and phenylglyoxylic acid: NHANES 2005-2006 and 2011-2012. Environ Res. 2019 Apr;171:101-110. [Content Brief]

[2]. Leont'eva L I, et al. Antiinflammatory activity of derivatives of phenylglyoxylic acid[J]. Pharmaceutical Chemistry Journal, 1993, 27(3): 195-197.

[3]. Jiang W, et al., Diversity of complexes based on p-nitrobenzoylhydrazide, benzoylformic acid and diorganotin halides or oxides self-assemble: Cytotoxicity, the induction of apoptosis in cancer cells and DNA-binding properties. Bioorg Chem. 2020 Jan;94:103402. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	5.6132 mL	28.0662 mL	56.1325 mL	140.3312 mL
	5 mM	1.1226 mL	5.6132 mL	11.2265 mL	28.0662 mL
	10 mM	0.5613 mL	2.8066 mL	5.6132 mL	14.0331 mL
	15 mM	0.3742 mL	1.8711 mL	3.7422 mL	9.3554 mL
	20 mM	0.2807 mL	1.4033 mL	2.8066 mL	7.0166 mL
	25 mM	0.2245 mL	1.1226 mL	2.2453 mL	5.6132 mL
	30 mM	0.1871 mL	0.9355 mL	1.8711 mL	4.6777 mL
	40 mM	0.1403 mL	0.7017 mL	1.4033 mL	3.5083 mL
	50 mM	0.1123 mL	0.5613 mL	1.1226 mL	2.8066 mL
	60 mM	0.0936 mL	0.4678 mL	0.9355 mL	2.3389 mL
	80 mM	0.0702 mL	0.3508 mL	0.7017 mL	1.7541 mL
	100 mM	0.0561 mL	0.2807 mL	0.5613 mL	1.4033 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Phenylglyoxylic acid-d₅ sodium Related Classifications

Metabolic Disease Inflammation/Immunology

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Phenylglyoxylic acid-d₅2708283-39-8Benzoylformic acid-d5sodium Sodium phenylglyoxylate-d5Drug IntermediateEndogenous MetaboliteIsotope-Labeled CompoundsDrug IintermediateInhibitorinhibitorinhibit

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Phenylglyoxylic acid-d5 sodium (Synonyms: Benzoylformic acid-d5sodium; Sodium phenylglyoxylate-d5)

Other Forms of Phenylglyoxylic acid-d5 sodium:

Phenylglyoxylic acid-d5 sodium Related Antibodies

Recomendaciones destacadas

•Related Small Molecules:

•Related Proteins:

Ver todos los productos específicos de isoformas Endogenous Metabolite:

Actividad biológica

Pureza y Documentación

Referencias

Revisión del cliente

Phenylglyoxylic acid-d5 sodium Related Antibodies

Calculadora de molaridad

Calculadora de dilución

Complete Stock Solution Preparation Table

Phenylglyoxylic acid-d5 sodium Related Classifications