Poly-L-lysine hydrobromide (MW 150000-300000)

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Poly-L-lysine (hydrobromide) (MW 150000-300000), a positively charged amino acid polymer, is a nonspecific attachment factor for cells. Poly-L-lysine (hydrobromide) (MW 150000-300000) has good biocompatibility. Poly-L-lysine (hydrobromide) (MW 150000-300000) is used to increase cell adhesion to solid substrates by enhancing electrostatic interaction between negatively charged ions of the cell membrane and the culture surface.

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Poly-L-lysine hydrobromide (MW 150000-300000) Estructura química

No. CAS : 25988-63-0

Tamaño	Stock	Cantidad
5 mg	En stock	Estimated Time of Arrival: December 31
10 mg	En stock	Estimated Time of Arrival: December 31
25 mg	En stock	Estimated Time of Arrival: December 31
50 mg	En stock	Estimated Time of Arrival: December 31
100 mg	Obtener un presupuesto
200 mg	Obtener un presupuesto

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Other Forms of Poly-L-lysine hydrobromide (MW 150000-300000):

Poly-L-lysine hydrobromide (MW 30000-70000) In-stock
Poly-L-lysine hydrochloride In-stock
Poly-L-lysine hydrobromide (MW 70000-150000) In-stock
Poly-L-lysine hydrobromide (MW ＞300000) In-stock

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Descripciòn	Poly-L-lysine (hydrobromide) (MW 150000-300000), a positively charged amino acid polymer, is a nonspecific attachment factor for cells. Poly-L-lysine (hydrobromide) (MW 150000-300000) has good biocompatibility. Poly-L-lysine (hydrobromide) (MW 150000-300000) is used to increase cell adhesion to solid substrates by enhancing electrostatic interaction between negatively charged ions of the cell membrane and the culture surface^[1].
In Vitro	Poly-L-lysine (hydrobromide) (MW 150000-300000) binds to the hydroxyl groups on the surface of magnetic nanoparticles through its amino groups, forms a stable coating layer, prevents the agglomeration and sedimentation of magnetic nanoparticles. Poly-L-lysine (hydrobromide) (MW 150000-300000) modifies magnetic nanoparticles, improves biocompatibility, and can be used as an antibody coupling platform^[2]. Poly-L-lysine (hydrobromide) (MW 150000-300000) acts as a cationic polymer, forms a polyelectrolyte complex (PEC) with anionic methacrylated gellan gum (GG-MA), thereby forming a semipermeable membrane around the GG-MA hydrogel. Poly-L-lysine (hydrobromide) (MW 150000-300000) regulate the permeability of GG-MA/PLL PEC beads, allowing the free diffusion of small molecules while preventing the entry of large molecules, thereby achieving the immune isolation of cells^[3]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Poly-L-lysine hydrobromide (MW 150000-300000) Related Antibodies
Peso molecular	150000-300000
Fòrmula	C₈H₁₉BrN₂O
No. CAS	25988-63-0
Appearance	Solid
Color	White to yellow
SMILES	CN[C@@H](CCCC[NH3+])C(C)=O.[n].[Br-].[n]
Envío	Room temperature in continental US; may vary elsewhere.
Almacenamiento	4°C, sealed storage, away from moisture and light *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvente y solubilidad	In Vitro: H₂O : 25 mg/mL (Need ultrasonic) Calculadora de molaridad Calculadora de dilución Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol) Mass = Concentration × Volume × Molecular Weight * Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final) This equation is commonly abbreviated as: C₁V₁ = C₂V₂ Concentration _(start) C1 × Volume _(start) V1 = Concentration _(final) C2 × Volume _(final) V2 In Vivo: Select the appropriate dissolution method based on your experimental animal and administration route. For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents: To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day. The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution. Protocol 1 Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline Solubility: ≥ 2.5 mg/mL; Clear solution This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown). Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL. Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution. Protocol 2 Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline) Solubility: ≥ 2.5 mg/mL; Clear solution This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown). Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly. Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear. In Vivo Dissolution Calculator Please enter the basic information of animal experiments: Dosage mg/kg Animal weight (per animal) g Dosing volume (per animal) μL Number of animals Recommended: Prepare an additional quantity of animals to account for potential losses during experiments. Calculation results: Working solution concentration: mg/mL This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details. The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE). Tel: 609-228-6898 E-mail: [email protected] Technical Support: [email protected]
Pureza y Documentación	Select Batch: Ficha de datos (272 KB) SDS (393 KB) COA (246 KB) Instrucciones de manejo (2659 KB)
Referencias	[1]. D Mazia, et al. Adhesion of cells to surfaces coated with polylysine. Applications to electron microscopy. J Cell Biol. 1975 Jul;66(1):198-200. [Content Brief] [2]. Kubovcikova M, et al. Poly-L-lysine designed magnetic nanoparticles for combined hyperthermia, magnetic resonance imaging and cancer cell detection. Journal of Magnetism and Magnetic Materials, 2019, 475: 316-326. [3]. Vieira S, et al., Methacrylated Gellan Gum/Poly-l-lysine Polyelectrolyte Complex Beads for Cell-Based Therapies. ACS Biomater Sci Eng. 2021 Oct 11;7(10):4898-4913. [Content Brief]