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  3. Polyaminopropyl biguanide

Polyaminopropyl biguanide (PAPB) is a positively charged antimicrobial polymer and cosmetic preservative. Polyaminopropyl biguanide inhibits the growth and division of negatively charged microorganisms via charge-based adsorption. Polyaminopropyl biguanide exhibits broad-spectrum in vitro activity against foodborne microorganisms and postharvest fruit pathogens. Polyaminopropyl biguanide can be used in studies related to citrus postharvest diseases and foodborne bacterial infections.

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Polyaminopropyl biguanide

Polyaminopropyl biguanide Chemische Struktur

CAS. Nr. : 133029-32-0

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Beschreibung

Polyaminopropyl biguanide (PAPB) is a positively charged antimicrobial polymer and cosmetic preservative. Polyaminopropyl biguanide inhibits the growth and division of negatively charged microorganisms via charge-based adsorption. Polyaminopropyl biguanide exhibits broad-spectrum in vitro activity against foodborne microorganisms and postharvest fruit pathogens. Polyaminopropyl biguanide can be used in studies related to citrus postharvest diseases and foodborne bacterial infections[2].

In Vitro

Polyaminopropyl biguanide (0.125-0.25%) significantly enhances the tensile strength and elongation at break of PEC/PVA composite films, with the 0.25% formulation exhibiting the highest tensile strength of up to 26.90 MPa[2].
Polyaminopropyl biguanide (0.125-1%) reduces the diffraction peak intensity of PEC/PVA composite films and improves their thermal stability in a concentration-dependent manner[2].
The polyaminopropyl biguanide/PEC/PVA composite films (0.125-1%) exhibit potent in vitro antibacterial activity, including 100% inhibition of Penicillium italicum at a polyaminopropyl biguanide concentration of 0.125%, and show stronger activity against Staphylococcus aureus than against Escherichia coli[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Formel

(C5H14N6)n

CAS. Nr.
Appearance

Solid

Color

White to off-white

SMILES

N=C(NC(NCCCN)=N)N.[n]

Versand

Room temperature in continental US; may vary elsewhere.

Speicherung
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Lösungsmittel & Löslichkeit
In Vitro: 

DMSO : 50 mg/mL (Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Produktname:
Polyaminopropyl biguanide
Art. -Nr.:
HY-158761
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