1. Immunology/Inflammation
  2. Toll-like Receptor (TLR)
  3. PTD-N5-1

PTD-N5-1 (N5-1) is an IRF5 inhibitory peptide. PTD-N5-1 blocks β-glucan-induced IL-12 production in IFN-γ primed wild-type and Clec2d-difecient bone-marrow-derived dendritic cells (BMDCs). PTD-N5-1 regulates antifungal immunity through suppression of IRF5-mediated IL-12 production.

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Kundenspezifische Peptidsynthese

PTD-N5-1

PTD-N5-1 Chemische Struktur

CAS. Nr. : 2088834-68-6

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Beschreibung

PTD-N5-1 (N5-1) is an IRF5 inhibitory peptide. PTD-N5-1 blocks β-glucan-induced IL-12 production in IFN-γ primed wild-type and Clec2d-difecient bone-marrow-derived dendritic cells (BMDCs). PTD-N5-1 regulates antifungal immunity through suppression of IRF5-mediated IL-12 production[1].

Molekulargewicht

3267.95

Formel

C148H248N52O30S

CAS. Nr.
Sequence

Asp-Arg-Gln-Ile-Lys-Ile-Trp-Phe-Gln-Asn-Arg-Arg-Met-Lys-Trp-Lys-Lys-Pro-Arg-Arg-Val-Arg-Leu-Lys

Sequence Shortening

DRQIKIWFQNRRMKWKKPRRVRLK

Versand

Room temperature in continental US; may vary elsewhere.

Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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PTD-N5-1
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