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(R)-BAY-85-8501 

Cat. No.: HY-19908B
Handling Instructions

(R)-BAY-85-8501 is the less active Enantiomer of BAY-85-8501. BAY-85-8501 is a selective and potent inhibitor of Human Neutrophil Elastase (HNE), with an IC50 of 65 pM.

For research use only. We do not sell to patients.

(R)-BAY-85-8501 Chemical Structure

(R)-BAY-85-8501 Chemical Structure

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 495 In-stock
Estimated Time of Arrival: December 31
5 mg USD 450 In-stock
Estimated Time of Arrival: December 31
10 mg USD 750 In-stock
Estimated Time of Arrival: December 31
25 mg USD 1750 In-stock
Estimated Time of Arrival: December 31
50 mg USD 2100 In-stock
Estimated Time of Arrival: December 31
100 mg USD 3300 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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Customer Review

Based on 2 publication(s) in Google Scholar

Other Forms of (R)-BAY-85-8501:

Top Publications Citing Use of Products

Publications Citing Use of MCE (R)-BAY-85-8501

    (R)-BAY-85-8501 purchased from MCE. Usage Cited in: Chinese Academy of Sciences. 2019 Aug.

    Blood from 3 healthy individuals, was separated using Lymhoprep, neutrophils isolated and plated out in 96 well plates at 5x105 and incubated with PMA (50 nM) for 3 hours, with and without inhibitor as above. Results show that BAY-85-8501 inhibits human neutrophil elastase at all 3 concentrations (50, 25, and 12.5 µM) with a significance of P<0.0001, when compared to the positive control of human neutrophil elastase and cells incubated with PMA and vehicle.
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    Description

    (R)-BAY-85-8501 is the less active Enantiomer of BAY-85-8501. BAY-85-8501 is a selective and potent inhibitor of Human Neutrophil Elastase (HNE), with an IC50 of 65 pM[1].

    Molecular Weight

    474.46

    Formula

    C₂₂H₁₇F₃N₄O₃S

    SMILES

    N#CC1=C(C)N(C2=CC=CC(C(F)(F)F)=C2)C(N(C)[[email protected]]1C3=CC=C(C#N)C=C3S(=O)(C)=O)=O

    Shipping

    Room temperature in continental US; may vary elsewhere

    Storage

    Please store the product under the recommended conditions in the Certificate of Analysis.

    References
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    Product Name:
    (R)-BAY-85-8501
    Cat. No.:
    HY-19908B
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