2. Epigenetics
  3. DNA Methyltransferase
  4. (Rac)-RG108

(Rac)-RG108  (Synonyms: (Rac)-N-Phthalyl-L-tryptophan)

Cat. No.: HY-13642A
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(Rac)-RG108 (NSC401077), a DNMT1 inhibitor, inhibits DNA methyltransferases.

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(Rac)-RG108

(Rac)-RG108 화학구조

CAS No. : 32675-71-1

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10 mg Ask For Quote & Lead Time

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Other Forms of (Rac)-RG108:

(Rac)-RG108 Related Antibodies

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DNA Methyltransferase DNMT1 DNMT3 MGMT

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제품 설명

(Rac)-RG108 (NSC401077), a DNMT1 inhibitor, inhibits DNA methyltransferases[1].

Cellular Effect
Cell Line Type Value Description References
NALM-6 IC50
50 3
Compound: NSC-401077
Inhibitory activity against DNA methyl transferase in leukemic NALM6 cells
Inhibitory activity against DNA methyl transferase in leukemic NALM6 cells
[PMID: 16420053]
HEK293 CC50
>20 3
Compound: MMV452821
Cytotoxicity against HEK293 cells (CO-ADD:MA_007); CC50 by cell viability assay in DMEM (10% FBS) media using TC plates, by Resazurin F(560/590)
Cytotoxicity against HEK293 cells (CO-ADD:MA_007); CC50 by cell viability assay in DMEM (10% FBS) media using TC plates, by Resazurin F(560/590)
10.6019/CHEMBL4296181
NALM-6 IC50
50 3
Compound: NSC-401077
Inhibitory activity against DNA methyl transferase in leukemic NALM6 cells
Inhibitory activity against DNA methyl transferase in leukemic NALM6 cells
[PMID: 16420053]
분자량

334.33

화학식

C19H14N2O4
CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

O=C(C(CC1=CNC2=C1C=CC=C2)N3C(C4=C(C3=O)C=CC=C4)=O)O
선적

Room temperature in continental US; may vary elsewhere.
보관
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
순도&문서
References
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(Rac)-RG108 Related Classifications

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  • 농도 희석 계산기

The molarity calculator equation

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(Rac)-RG10832675-71-1(Rac)-N-Phthalyl-L-tryptophanDNA MethyltransferaseDNMTsDNA MTasesInhibitorinhibitorinhibit

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상품명:
(Rac)-RG108
Cat. No.:
HY-13642A
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