1. Signaling Pathways
  2. Epigenetics
  3. DNA Methyltransferase
  4. DNMT3 Inhibitors

DNMT3 Inhibitors

DNA Methyltransferase

DNMT1

DNMT3

MGMT

Your Search Returned No Results.

Sorry. There is currently no product that acts on isoform DNMT3 together.

Please try each isoform separately.

DNMT3 Specific Inhibitors
Product Name DNMT3 DNA Methyltransferase DNMT1 DNMT3 Selectivity Purity
Decitabine
DNMT3A
DNMT3B
 
DNMT1
Pan Inhibitor 99.99%
SGI-1027
DNMT3B, IC50: 7.5 μM
DNMT3A, IC50: 8 μM
 
DNMT1, IC50: 12.5 μM
Pan Inhibitor 99.92%
Zebularine
DNMT3a/3L
 
DNMT1
Pan Inhibitor 99.92%
γ-Oryzanol
DNMT3A, IC50: 22.3 μM
 
DNMT1, IC50: 3.2 μM
Pan Inhibitor >95.0%
CM-579 trihydrochloride
DNMT3A, IC50: 92 nM
DNMT3B, IC50: 1000 nM
DNA Methyltransferase, IC50: 32 nM
DNMT1, Kd: 1.5 nM
Pan Inhibitor 98.03%
CM-579
DNMT3A, IC50: 92 nM
DNMT3B, IC50: 1000 nM
DNA Methyltransferase, IC50: 32 nM
DNMT1, Kd: 1.5 nM
Pan Inhibitor