2. Signaling Pathways
  3. Epigenetics
  4. DNA Methyltransferase
  5. DNMT3 Isoform

DNMT3

 

DNMT3 Related Products (11):

Cat. No. Product Name Effect Purity
  • HY-A0004
    Decitabine
    		Inhibitor 99.97%
    Decitabine (NSC 127716) is an orally active deoxycytidine analogue antimetabolite and a DNA methyltransferase inhibitor.
  • HY-13962
    SGI-1027
    		Inhibitor 99.35%
    SGI-1027 is a DNA methyltransferase (DNMT) inhibitor, with IC50s of 7.5 μM, 8 μM, and 12.5 μM for DNMT3B, DNMT3A, and DNMT1 with poly(dI-dC) as substrate.
  • HY-101925
    CM-272
    		Inhibitor 99.27%
    CM-272 is a first-in-class, potent, selective, substrate-competitive and reversible dual G9a/DNA methyltransferases (DNMTs) inhibitor with antitumor activities.
  • HY-13420
    Zebularine
    		Inhibitor 99.99%
    Zebularine (NSC309132; 4-Deoxyuridine) is a DNA methyltransferase inhibitor.
  • HY-B2194
    γ-Oryzanol
    		Inhibitor
    γ-Oryzanol is a potent DNA methyltransferases (DNMTs) inhibitor in the striatum of mice.
  • HY-117421A
    CM-579 trihydrochloride
    		Inhibitor 98.03%
    CM-579 trihydrochloride is a first-in-class reversible, dual inhibitor of G9a and DNMT, with IC50 values of 16 nM, 32 nM for G9a and DNMT, respectively.
  • HY-144433
    DNMT3A-IN-1
    		Inhibitor 98.81%
    DNMT3A-IN-1 is a potent and selective DNMT3A inhibitor.
  • HY-103397
    Nanaomycin A
    		Inhibitor 98.18%
    Nanaomycin A is the first selective DNMT3B inhibitor with an IC50 of 500 nM.
  • HY-117421
    CM-579
    		Inhibitor
    CM-579 is a first-in-class reversible, dual inhibitor of G9a and DNMT, with IC50 values of 16 nM, 32 nM for G9a and DNMT, respectively.
  • HY-151136
    DY-46-2
    		Inhibitor
    DY-46-2 is a high potency and selectivity novel non-nucleoside DNA methyltransferase 3A (DNMT3A) inhibitor with an IC50 value of 0.39 μM.
  • HY-150025
    (4aS,8aR)-NPD-001
    		Inhibitor
    (4aS,8aR)-NPD-001 is a potent and allosteric inhibitor of DNMT3A.