2448471-08-5

CM-579 trihydrochloride Chemical Structure
2448471-08-5

Chemical Structure

CM-579 trihydrochloride

  • CAS No.: 2448471-08-5
  • Formula:C29H43Cl3N4O3
  • Molecular Weight:602.04

IUPAC Name: 6-methoxy-2-(5-methylfuran-2-yl)-N-((1-methylpiperidin-4-yl)methyl)-7-(3-(pyrrolidin-1-yl)propoxy)quinolin-4-amine trihydrochloride

InChIKey: XKSDREMVFCQUPC-UHFFFAOYSA-N

SMILES: CN1CCC(CNC2=CC(C3=CC=C(C)O3)=NC4=CC(OCCCN5CCCC5)=C(OC)C=C24)CC1.Cl.Cl.Cl

Biological Activity: CM-579 trihydrochloride is a first-in-class reversible, dual inhibitor of G9a and DNMT, with IC50 values of 16 nM, 32 nM for G9a and DNMT, respectively. Has potent in vitro cellular activity in a wide range of cancer cells[1].

Cat. No. Product Name Purity Description Pricing
HY-117421A
CM-579 trihydrochloride 97.00% CM-579 trihydrochloride is a first-in-class reversible, dual inhibitor of G9a and DNMT, with IC50 values of 16 nM, 32 nM for G9a and DNMT, respectively. Has potent in vitro cellular activity in a wide range of cancer cells.
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