DNMT/HDAC-IN-2
DNMT/HDAC-IN-2 (Compound Y7) is a DNMT and HDAC inhibitor with IC50 values for DNMT1, HDAC1, and HDAC6 of 365, 0.2, and 8.91 nM respectively. DNMT/HDAC-IN-2 inhibits the proliferation of breast cancer cells. DNMT/HDAC-IN-2 significantly reduces tumor growth in xenografts and transgenic breast cancer mouse models. DNMT/HDAC-IN-2 can be used for the study of breast cancer.
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- No. CAS: 2548725-57-9
- Fòrmula: C28H38N4O5
- Peso molecular:510.63
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
Descripciòn
IC50 & Target
[1]|
HDAC1 0.2 nM (IC50) |
HDAC6 8.91 nM (IC50) |
DNMT1 365 nM (IC50) |
Chemical Information
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No. CAS 2548725-57-9
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Peso molecular 510.63
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Fòrmula C28H38N4O5
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SMILES
COC1=C(C=C(C2=C1)N=C(C=C2NC3CCN(CC3)C)C4=CC=C(O4)C)OCCCCCCC(NO)=O
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
DNMT/HDAC-IN-2 Related Classifications
HY-175988 Related Classifications
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