1. Signaling Pathways
  2. Epigenetics
  3. DNA Methyltransferase
  4. DNA Methyltransferase Inhibitors

DNA Methyltransferase Inhibitors

DNA Methyltransferase

DNMT1

DNMT3

MGMT

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Sorry. There is currently no product that acts on isoform together.

Please try each isoform separately.

DNA Methyltransferase Inhibitors
Product Name DNA Methyltransferase DNMT1 DNMT3 MGMT Purity
Decitabine  
DNMT1
DNMT3A
DNMT3B
  99.97%
5-Azacytidine  
DNMT1
    99.79%
GSK-3484862  
DNMT1
    99.62%
SGI-1027  
DNMT1, IC50: 12.5 μM
DNMT3B, IC50: 7.5 μM
DNMT3A, IC50: 8 μM
  99.77%
RG108  
CpG methylase M.SssI, IC50: 115 nM
    99.85%
Hinokitiol  
DNMT1
    98.97%
CM-272  
DNMT1, IC50: 382 nM
DNMT3A, IC50: 85 nM
DNMT3B, IC50: 1200 nM
  99.27%
Zebularine  
DNMT1
DNMT3a/3L
  99.99%
Guadecitabine sodium  
DNMT1
    98.05%
γ-Oryzanol  
DNMT1, IC50: 3.2 μM
DNMT3A, IC50: 22.3 μM
 
DNMT3A-IN-1    
DNMT3A
  98.81%
Lomeguatrib      
MGMT, IC50: 9 nM
MGMT, IC50: 6 nM (in MCF-7 cells)
99.70%
CM-579 trihydrochloride
DNA Methyltransferase, IC50: 32 nM
DNMT1, Kd: 1.5 nM
DNMT3A, IC50: 92 nM
DNMT3B, IC50: 1000 nM
  98.03%
DY-46-2    
DNMT3A, IC50: 0.39 μM
  99.12%
DC_517  
DNMT1, Kd: 0.91 μM
DNMT1, IC50: 1.7 μM
    99.41%
(R)-GSK-3685032  
DNMT1
    98.02%
O6BTG-octylglucoside      
MGMT, IC50: 32 nM
DC-05  
DNMT1, Kd: 1.09 μM
DNMT1, IC50: 10.3 μM
    99.08%
Guadecitabine
DNA Methyltransferase
      98.0%
CM-579
DNA Methyltransferase, IC50: 32 nM
DNMT1, Kd: 1.5 nM
DNMT3A, IC50: 92 nM
DNMT3B, IC50: 1000 nM
 
Nanaomycin A    
DNMT3B, IC50: 500 nM
  98.18%
Isofistularin-3  
DNMT1, IC50: 13.5 μM
   
(4aS,8aR)-NPD-001    
DNMT3A
 
DNMT-IN-1
DNA Methyltransferase, EC50: 3.2 μM