2. Metabolic Enzyme/Protease Neuronal Signaling GPCR/G Protein
  3. Drug Metabolite Adrenergic Receptor
  4. (±)-Desisopropylpropranolol

(±)-Desisopropylpropranolol  (Synonyms: N-Desisopropylpropranolol)

Cat. No.: HY-W192276
Handling Instructions Technical Support

(±)-Desisopropylpropranolol (N-Desisopropylpropranolol) is a metabolite of Propranolol (HY-B0573B). Propranolol is a nonselective β-adrenergic receptor (βAR) antagonist, has high affinity for the β1AR and β2AR with Kis of 1.8 nM and 0.8 nM, respectively. Propranolol inhibits [3H]-DHA binding to rat brain membrane preparation with an IC50 of 12 nM. Propranolol is used for the study of hypertension, pheochromocytoma, myocardial infarction, cardiac arrhythmias, angina pectoris, and hypertrophic cardiomyopathy.

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(±)-Desisopropylpropranolol

(±)-Desisopropylpropranolol 화학구조

CAS No. : 20862-11-7

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Other Forms of (±)-Desisopropylpropranolol:

(±)-Desisopropylpropranolol Related Antibodies

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제품 설명

(±)-Desisopropylpropranolol (N-Desisopropylpropranolol) is a metabolite of Propranolol (HY-B0573B). Propranolol is a nonselective β-adrenergic receptor (βAR) antagonist, has high affinity for the β1AR and β2AR with Kis of 1.8 nM and 0.8 nM, respectively. Propranolol inhibits [3H]-DHA binding to rat brain membrane preparation with an IC50 of 12 nM. Propranolol is used for the study of hypertension, pheochromocytoma, myocardial infarction, cardiac arrhythmias, angina pectoris, and hypertrophic cardiomyopathy[1][2][3][4].

IC50 & Target[1]

β adrenergic receptor

 

분자량

217.26

화학식

C13H15NO2
CAS No.
SMILES

C1=CC=C2C(=C1)C=CC=C2OCC(CN)O
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
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(±)-Desisopropylpropranolol Related Classifications

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This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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C1   V1   C2   V2
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(±)-Desisopropylpropranolol20862-11-7N-DesisopropylpropranololDrug MetaboliteAdrenergic ReceptorBeta ReceptorInhibitorinhibitorinhibit

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상품명:
(±)-Desisopropylpropranolol
Cat. No.:
HY-W192276
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