1. Others Metabolic Enzyme/Protease
  2. Endogenous Metabolite Isotope-Labeled Compounds
  3. Ribitol-13C5

Ribitol-13C5  (Synonyms: Adonitol-13C5; Adonite-13C5)

Cat. No.: HY-W768324 Purity: 99.77%
Handling Instructions Technical Support

Ribitol-13C5 (Adonitol-13C5) is the 13C-labeled Ribitol (HY-100582). Ribitol is a crystalline pentose alcohol formed by the reduction of ribose. Enhancing the flux of D-glucose to the pentose phosphate pathway in Saccharomyces cerevisiae for the production of D-ribose and ribitol.

For research use only. We do not sell to patients.

Ribitol-<sup>13</sup>C<sub>5</sub>

Ribitol-13C5 Chemical Structure

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Description

Ribitol-13C5 (Adonitol-13C5) is the 13C-labeled Ribitol (HY-100582). Ribitol is a crystalline pentose alcohol formed by the reduction of ribose. Enhancing the flux of D-glucose to the pentose phosphate pathway in Saccharomyces cerevisiae for the production of D-ribose and ribitol.

Application

1. This compound can be used as a tracer.
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

157.11

Formula

13C5H12O5

Unlabeled CAS
Appearance

Solid

Color

White to off-white

SMILES

O[13CH2][13C@@H]([13C@@H]([13C@@H]([13CH2]O)O)O)O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : ≥ 50 mg/mL (318.25 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 6.3650 mL 31.8248 mL 63.6497 mL
5 mM 1.2730 mL 6.3650 mL 12.7299 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 6.3650 mL 31.8248 mL 63.6497 mL 159.1242 mL
5 mM 1.2730 mL 6.3650 mL 12.7299 mL 31.8248 mL
10 mM 0.6365 mL 3.1825 mL 6.3650 mL 15.9124 mL
15 mM 0.4243 mL 2.1217 mL 4.2433 mL 10.6083 mL
20 mM 0.3182 mL 1.5912 mL 3.1825 mL 7.9562 mL
25 mM 0.2546 mL 1.2730 mL 2.5460 mL 6.3650 mL
30 mM 0.2122 mL 1.0608 mL 2.1217 mL 5.3041 mL
40 mM 0.1591 mL 0.7956 mL 1.5912 mL 3.9781 mL
50 mM 0.1273 mL 0.6365 mL 1.2730 mL 3.1825 mL
60 mM 0.1061 mL 0.5304 mL 1.0608 mL 2.6521 mL
80 mM 0.0796 mL 0.3978 mL 0.7956 mL 1.9891 mL
100 mM 0.0636 mL 0.3182 mL 0.6365 mL 1.5912 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Ribitol-13C5
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