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Results for "

(±)-Leucine (Standard)

" in MedChemExpress (MCE) Product Catalog:

25

Inhibitors & Agonists

5

Peptides

14

Natural
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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N0486R
    L-Leucine (Standard)
    1 Publications Verification

    Leucine (Standard)

    		 Reference Standards mTOR Endogenous Metabolite Metabolic Disease
    L-Leucine (Standard) is the analytical standard of L-Leucine. This product is intended for research and analytical applications. L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway .
    L-Leucine (Standard)
  • HY-W040088R
    L-Alanyl-L-leucine (Standard)

    H-Ala-Leu-OH (Standard)

    		 Reference Standards Aminopeptidase Metabolic Disease
    L-Alanyl-L-leucine is an endogenous metabolite. This product is used for research and analytical applications. L-Alanyl-L-leucine is a competitive inhibitor of small intestinal glycyl-L-leucine hydrolase with Ki values of 0.53 mM (phosphate buffer) or 0.22 mM (Tris buffer). L-Alanyl-L-leucine can be used for research on Hartnup disease and cystinuria .
    L-Alanyl-L-leucine (Standard)
  • HY-Y0017R
    L-Norleucine (Standard)

    (S)-2-Aminohexanoic acid (Standard); (S)-NorLeucine (Standard)

    		 Reference Standards Influenza Virus Endogenous Metabolite Infection Cancer
    L-Norleucine (Standard) is the analytical standard of L-Norleucine. This product is intended for research and analytical applications. L-Norleucine ((S)-2-Aminohexanoic acid) is an isomer of leucine, specifically affects protein synthesis in skeletal muscle, and has antivirus activity.
    L-Norleucine (Standard)
  • HY-30215R
    (S)-Leucic acid (Standard)

    		Reference Standards Endogenous Metabolite Metabolic Disease Endocrinology
    (S)-Leucic acid (Standard) is the analytical standard of (S)-Leucic acid (HY-30215). This product is intended for research and analytical applications. (S)-Leucic acid is a metabolite of Leucine. (S)-Leucic acid has anabolic effects, particularly promoting muscle protein synthesis. (S)-Leucic acid can be used in the diagnosis of pregnancy loss .
    (S)-Leucic acid (Standard)
  • HY-B1442R
    Acetylleucine (Standard)

    N-Acetyl-DL-Leucine (Standard)

    		 Drug Derivative Reference Standards Neurological Disease
    Acetylleucine (Standard) is the analytical standard of Acetylleucine. This product is intended for research and analytical applications. Acetylleucine (N-Acetyl-DL-leucine), orally active compound, can be used for the research of acute vestibular vertigo, cerebellar ataxia and nystagmus .
    Acetylleucine (Standard)
  • HY-108357R
    6-Diazo-5-oxo-L-nor-Leucine (Standard)

    L-6-Diazo-5-oxonorLeucine (Standard); DON (Standard)

    		 Reference Standards Glutaminase Bacterial Influenza Virus Antibiotic Infection Cancer
    6-Diazo-5-oxo-L-nor-Leucine (Standard) is the analytical standard of 6-Diazo-5-oxo-L-nor-Leucine. This product is intended for research and analytical applications. 6-Diazo-5-oxo-L-nor-Leucine (L-6-Diazo-5-oxonorleucine; DON) is a glutamine antagonist that irreversibly inhibits the catabolic effect of glutamine. 6-Diazo-5-oxo-L-nor-Leucine shows good anticancer activity (especially in pancreatic cancer) and reduces the self-renewal potential and metastatic capacity of tumour cells. 6-Diazo-5-oxo-L-nor-Leucine also possesses antibacterial and antiviral activity[1][2][3].
    6-Diazo-5-oxo-L-nor-Leucine (Standard)
  • HY-B1674R
    (±)-Leucine (Standard)

    DL-Leucine (Standard); (RS)-Leucine (Standard)

    		 Reference Standards Endogenous Metabolite Bacterial Metabolic Disease
    (±)-Leucine (Standard) is the analytical standard of (±)-Leucine. This product is intended for research and analytical applications. (±)-Leucine (DL-Leucine), an isomer of Leucine, chemosterilant and dietary additive. (±)-Leucine inhibits growth of Escherichia coli HfrH by 92.08% .
    (±)-Leucine (Standard)
  • HY-145542R
    Isovalerylcarnitine chloride (Standard)

    		Reference Standards Proteasome Endogenous Metabolite Apoptosis Metabolic Disease Cancer
    Isovalerylcarnitine chloride (Standard) is the analytical standard of Isovalerylcarnitine chloride (HY-145542). This product is intended for research and analytical applications. Isovalerylcarnitine chloride is a metabolite of leucine. Isovalerylcarnitine can specifically activate calpain in human neutrophils. Isovalerylcarnitine chloride inhibits tumor cell proliferation and induces apoptosis. Elevated circulating levels of Isovalerylcarnitine chloride are negatively correlated with reduced lung cancer risk .
    Isovalerylcarnitine chloride (Standard)
  • HY-N7069R
    4-Isopropylbenzyl alcohol (Standard)

    		Reference Standards Others Cancer
    (±)-Leucine (Standard) is the analytical standard of (±)-Leucine. This product is intended for research and analytical applications. (±)-Leucine (DL-Leucine), an isomer of Leucine, chemosterilant and dietary additive. (±)-Leucine inhibits growth of Escherichia coli HfrH by 92.08% .
    4-Isopropylbenzyl alcohol (Standard)
  • HY-I0591R
    N-Formyl-L-leucine (Standard)

    N-Formyl-S-Leucine (Standard); N-FormylLeucine (Standard); NSC 334321 (Standard)

    		 Amino Acid Derivatives Reference Standards Others
    N-Formyl-L-leucine (Standard)
  • HY-W342021R
    Thr-Leu (Standard)

    H-Thr-Leu-OH (Standard); L-Threonyl-L-Leucine (Standard)

    		 Reference Standards Others Others
    Thr-Leu is a dipeptide composed of threonine and leucine. Thr-Leu can be hydrolyzed in the peritoneal cavity to generate constituent amino acids, thereby increasing the osmotic pressure of the dialysate. Thr-Leu can be used for the kinetic study of amino acid-based peritoneal dialysis fluids .
    Thr-Leu (Standard)
  • HY-N9960R
    α-Isopropylmalate (Standard)

    α-IPM (Standard)

    		 Reference Standards Others Others
    α-Isopropylmalate (Standard) is the analytical standard of α-Isopropylmalate. This product is intended for research and analytical applications. α-Isopropylmalate (α-IPM) is the leucine biosynthetic precursor in Yeast .
    α-Isopropylmalate (Standard)
  • HY-128434R
    L-Leucyl-L-alanine (Standard)

    		Reference Standards Endogenous Metabolite Metabolic Disease
    L-​Leucyl-​L-​alanine (Standard) is the analytical standard of L-​Leucyl-​L-​alanine (HY-128434). This product is intended for research and analytical applications. L-Leucyl-L-alanine is a simple aliphatic dipeptide composed of L-leucine and L-alanine .
    L-Leucyl-L-alanine (Standard)
  • HY-Y0378R
    D-Leucine (Standard)

    (R)-Leucine (Standard)

    		 Reference Standards Endogenous Metabolite Neurological Disease
    D-Leucine (Standard) is the analytical standard of D-Leucine. This product is intended for research and analytical applications. D-Leucine is a more potent anti-seizure agent than L-leucine. D-leucine potently terminates seizures even after the onset of seizure activity. D-leucine, but not L-leucine, reduces long-term potentiation but had no effect on basal synaptic transmission in vitro .
    D-Leucine (Standard)
  • HY-59135R
    (S)-2-(Methoxycarbonylamino)-3,3-dimethylbutanoic acid (Standard)

    		Amino Acid Derivatives Reference Standards Others
    (S)-2-(Methoxycarbonylamino)-3,3-dimethylbutanoic acid (Standard) is the analytical standard of (S)-2-(Methoxycarbonylamino)-3,3-dimethylbutanoic acid. This product is intended for research and analytical applications. (S)-2-(Methoxycarbonylamino)-3,3-dimethylbutanoic acid is a leucine derivative .
    (S)-2-(Methoxycarbonylamino)-3,3-dimethylbutanoic acid (Standard)
  • HY-W016077R
    Glycyl-L-leucine (Standard)

    		Reference Standards Endogenous Metabolite Others
    Glycyl-L-leucine (Standard) is the analytical standard of Glycyl-L-leucine. This product is intended for research and analytical applications. Glycyl-l-leucine is a dipeptide that can be a common substrate for glycyl-leucine dipeptidase.
    Glycyl-L-leucine (Standard)
  • HY-30216R
    (R)-Leucic acid (Standard)

    D-α-Hydroxyisocaproic acid (Standard)

    		 Reference Standards Amino Acid Derivatives Endogenous Metabolite Metabolic Disease
    (R)-Leucic acid (Standard) is the analytical standard of (R)-Leucic acid (HY-30216). This product is intended for research and analytical applications. (R)-Leucic acid (D-α-Hydroxyisocaproic acid) is the D-isomer of the α-hydroxy analogue of Leucine (HY-N0486). (R)-Leucic acid is a metabolite of Lactobacillus and can promote intestinal fatty acid absorption by upregulating CD36 expression. (R)-Leucic acid can be used to study microbe-host interactions and the regulation of lipid metabolism by probiotics.
    (R)-Leucic acid (Standard)
  • HY-N11200R
    3-Hydroxyisovalerylcarnitine (Standard)

    		Endogenous Metabolite Reference Standards Metabolic Disease
    3-Hydroxyisovalerylcarnitine (Standard) is the analytical standard of 3-Hydroxyisovalerylcarnitine. This product is intended for research and analytical applications. 3-Hydroxyisovalerylcarnitine is a carnitine derivative. 3-Hydroxyisovaleryl carnitine in plasma may serve as a novel biomarker of biotin deficiency in humans, with its concentration increasing with biotin deficiency. Biotin deficiency reduces the activity of biotin-dependent 3-methylcrotonyl-CoA carboxylase, hinders the conversion of 3-methylcrotonyl-CoA into 3-methylglutaconyl-CoA, and impairs the leucine catabolism pathway; resulting in plasma 3-Hydroxyisovalerylcarnitine concentrations rise .
    3-Hydroxyisovalerylcarnitine (Standard)
  • HY-113952R
    Actinonin (Standard)

    (-)-Actinonin (Standard)

    		 Reference Standards Aminopeptidase Bacterial MMP Apoptosis Antibiotic Infection Cancer
    Actinonin (Standard) is the analytical standard of Actinonin. This product is intended for research and analytical applications. Actinonin ((-)-Actinonin) is a naturally occurring antibacterial agent produced by Actinomyces. Actinonin inhibits aminopeptidase M, aminopeptidase N and leucine aminopeptidase. Actinonin is a potent reversible peptide deformylase (PDF) inhibitor with a Ki of 0.28 nM. Actinonin also inhibits MMP-1, MMP-3, MMP-8, MMP-9, and hmeprin α with Ki values of 300 nM, 1,700 nM, 190 nM, 330 nM, and 20 nM, respectively. Actinonin is an apoptosis inducer. Actinonin has antiproliferative and antitumor activities[1][2][3][4][5].
    Actinonin (Standard)
  • HY-101064R
    Fmoc-leucine (Standard)

    N-FMOC-Leucine (Standard); NPC 15199 (Standard); NSC 334290 (Standard)

    		 PPAR Reference Standards Metabolic Disease
    Fmoc-leucine (Standard) is the analytical standard of Fmoc-leucine (HY-101064). This product is intended for research and analytical applications. Fmoc-leucine is a selective PPARγ modulator. Fmoc-leucine activates PPARγ with a lower potency but a similar maximal efficacy than rosiglitazone. Fmoc-leucine improves insulin sensitivity in normal, diet-induced glucose-intolerant, and in diabetic db/db mice. Fmoc-leucine has a lower adipogenic activity .
    Fmoc-leucine (Standard)
  • HY-W008642R
    Leu-Leu-OH (Standard)

    L-Leucyl-L-Leucine (Standard); Leu-Leu (Standard); H-Leu-Leu-OH (Standard)

    		 Amino Acid Derivatives Reference Standards Metabolic Disease
    Leu-Leu-OH (Standard) is the analytical standard of Leu-Leu-OH (HY-W008642). This product is intended for research and analytical applications. Leu-Leu-OH (L-Leucyl-L-leucine), a Leu derivative, is a neutral dipeptide that can be used to study the functionality of dileucine motifs .
    Leu-Leu-OH (Standard)
  • HY-108900R
    Leu-AMS (Standard)

    		Reference Standards Aminoacyl-tRNA Synthetase Bacterial Infection Cancer
    Leu-AMS (Standard) is the analytical standard of Leu-AMS (HY-108900). This product is intended for research and analytical applications. Leu-AMS (compound 6), a leucine analogue, is a potent inhibitor of leucyl-tRNA synthetase (LRS) with an IC50 of 22.34 nM, which inhibits the catalytic activity of LRS but did not affect the leucine-induced mTORC1 activation. Leu-AMS shows cytotoxicity in cancer cells and normal cells, and inhibits the growth of bacteria .
    Leu-AMS (Standard)
  • HY-100368AR
    MELK-8a hydrochloride (Standard)

    NVS-MELK8a hydrochloride (Standard)

    		 MELK Reference Standards Cancer
    MELK-8a (hydrochloride) (Standard) is the analytical standard of MELK-8a (hydrochloride) (HY-100368A). This product is intended for research and analytical applications. MELK-8a hydrochloride is a novel maternal embryonic leucine zipper kinase (MELK) inhibitor with an IC50 of 2 nM.
    MELK-8a hydrochloride (Standard)
  • HY-101515R
    MELK-IN-1 (Standard)

    		MELK Reference Standards Cancer
    MELK-IN-1 (Standard) is the analytical standard of MELK-IN-1 (HY-101515). This product is intended for research and analytical applications. MELK-IN-1 is a potent inhibitor of maternal embryonic leucine zipper kinase (MELK) with an IC50 and a Ki of 3 nM and 0.39 nM, respectively.
    MELK-IN-1 (Standard)
  • HY-103423R
    PAOPA (Standard)

    		Reference Standards Dopamine Receptor Neurological Disease
    PAOPA (Standard) is the analytical standard of PAOPA (HY-103423). This product is intended for research and analytical applications. PAOPA, an analog of L-proline-l-leucine-glycine amide (PLG) peptide, is an allosteric modulator of Dopamine D2 Receptor. PAOPA can effectively reduce behavioral abnormalities in rodent models of schizophrenia. PAOPA increases the high affinity dopamine D2 receptor and promotes its binding to agonists .
    PAOPA (Standard)

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