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Cat. No.: HY-100368AR

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MELK-8a hydrochloride (Standard)

(Synonyms: NVS-MELK8a hydrochloride (Standard))

MELK-8a (hydrochloride) (Standard) is the analytical standard of MELK-8a (hydrochloride) (HY-100368A). This product is intended for research and analytical applications. MELK-8a hydrochloride is a novel maternal embryonic leucine zipper kinase (MELK) inhibitor with an IC50 of 2 nM.

For research use only. We do not sell to patients.

CAS No.: 2096992-20-8
Formula: C₂₅H₃₃ClN₆O
Molecular Weight:469.02

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

MELK-8a hydrochloride (Standard) Chemical Structure

CAS No.: 2096992-20-8

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Chemical Information
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Bioz

Product Information

Information

Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.

Chemical Information

CAS No. 2096992-20-8
Molecular Weight 469.02
Formula C₂₅H₃₃ClN₆O
SMILES

CN(CC1)CCN1C2=CC=C(N3C=C(C4=CC=NC=C4OCC5CCNCC5)C=N3)C=C2.Cl
Synonyms

NVS-MELK8a hydrochloride (Standard)
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

References

[1]. Touré BB, et al. Toward the Validation of Maternal Embryonic Leucine Zipper Kinase: Discovery, Optimization of Highly Potent and Selective Inhibitors, and Preliminary Biology Insight. J Med Chem. 2016 May 26;59(10):4711-23. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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