Search Result

Results for "

MBX

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Bacterial (4) CMV (1) GLP Receptor (1) GPR119 (2) Influenza Virus (2) Interleukin Related (1) P2X Receptor (1) PPAR (8) Reference Standards (1) Small Interfering RNA (siRNA) (1) Thyroid Hormone Receptor (1)
By Research Areas:	Cancer (1) Cardiovascular Disease (2) Endocrinology (1) Infection (6) Inflammation/Immunology (2) Metabolic Disease (11) Neurological Disease (1)
Oligonucleotides:	Human Pre-designed siRNA Sets (1) siRNAs (1)

Inhibitors & Agonists

Peptides

Oligonucleotides

Cat. No.	상품명	Target	연구분야	Chemical Structure

HY-19522

Seladelpar 1 Publications Verification MBX-8025; RWJ-800025	PPAR	Metabolic Disease
Seladelpar (MBX-8025) is an orally active, potent and specific PPARδ agonist with an EC₅₀ of 2 nM. Seladelpar shows more than 750-fold and 2500-fold selectivity over the PPARα and PPARγ receptors, respectively. Seladelpar can be used for the study of primary biliary cholangitis .

HY-15291

MBX-2982 Maximum Cited Publications 12 Publications Verification	GPR119	Metabolic Disease
MBX-2982 is a selective, orally-available G protein-coupled receptor 119 (GPR119) agonist.

HY-P10957

Imapextide MBX 1416	GLP Receptor	Metabolic Disease
Imapextide is a glucagon-like peptide-1 (GLP-1) receptor antagonist that can be used in hypoglycemia research .

HY-112565

MBX-4132 2 Publications Verification	Bacterial	Infection
MBX-4132, a member of a chemical class called oxadiazoles that inhibit trans translation by binding to the bacterial ribosome.

HY-P10909

Canvuparatide MBX 2109	Thyroid Hormone Receptor	Endocrinology
Canvuparatide (MBX 2109) is a prodrug for parathyroid hormone (PTH) peptide that releases the bioactive PTH[1-32] peptide agonist that retains a fatty acylated lysine (Lys33) at the C-terminus, thereby extending the halflife of Canvuparatide. Canvuparatide can be used for the symptoms of hypoparathyroidism such as hypocalcemia and hyperphosphatemia .

HY-19522A

Seladelpar sodium 1 Publications Verification MBX-8025 sodium; RWJ-800025 sodium	PPAR	Metabolic Disease Inflammation/Immunology
Seladelpar (MBX-8025) sodium salt is an orally active, potent and specific PPARδ agonist with an EC₅₀ of 2 nM. Seladelpar sodium salt shows more than 750-fold and 2500-fold selectivity over the PPARα and PPARγ receptors, respectively. Seladelpar sodium salt hydrochloride can be used for the study of primary biliary cholangitis .

HY-16721

Cyclopropavir Filociclovir; ZSM-I-62; MBX-400	CMV	Infection
Cyclopropavir (Filociclovir) is an orally active and broad-spectrum anti-herpesvirus compound. Cyclopropavir inhibits UL97 kinase activity. Cyclopropavir has antiviral activity against HCMV, MCMV, and HAdV6 viruses .

HY-14831

Arhalofenate 1 Publications Verification MBX 102; JNJ 39659100	PPAR	Metabolic Disease
Arhalofenate (MBX 102) is a selective partial agonist of peroxisome proliferator-activated receptor (PPAR)-γ, used for the treatment of type 2 diabetes.

HY-19522C

Seladelpar (lysine dihydrate) 1 Publications Verification MBX-8025 (lysine dihydrate); RWJ-800025 (lysine dihydrate)	PPAR Interleukin Related	Cardiovascular Disease Metabolic Disease Inflammation/Immunology
Seladelpar Lysine dihydrate (MBX-8025 lysine dihydrate) is an orally active, selective PPAR-δ agonist with an EC₅₀ of 2 nM against hPPAR-δ. Seladelpar Lysine dihydrate reduces serum IL-31 and bile acid levels. It alleviates pruritus symptoms. Seladelpar Lysine dihydrate enhances insulin sensitivity, normalizes levels of hyperglycemia, hyperinsulinemia, glucose disposal capacity, serum lipids and hepatic free cholesterol. It reduces steatosis, hepatic inflammation and improves liver fibrosis. Seladelpar Lysine dihydrate reverses the pathological changes of non-alcoholic steatohepatitis (NASH). It is applicable to research related to primary biliary cholangitis and non-alcoholic steatohepatitis (NASH) .

HY-123304

MBX2546	Influenza Virus	Infection
MBX2546 is a influenza A virus inhibitor with the K_d values of 5.3μM and ＞ 100 μM for H1 Hemagglutinin and H3 Hemagglutinin, respectively .

HY-131069A

MBX2329	Influenza Virus	Infection
MBX2329, a potent influenza virus inhibitor, specifically inhibits hemagglutinin (HA)-mediated viral entry with HIV/HA(H5) displaying IC₉₀ of 8.6 μM. MBX2329 inhibits a wide spectrum of influenza A viruses, which includes the 2009 pandemic influenza virus A/H1N1/2009, highly pathogenic avian influenza (HPAI) virus A/H5N1, and oseltamivir-resistant A/H1N1 strains .

HY-157987

MBX3135	Bacterial	Infection
MBX3135 is an efflux pump inhibitor which can enhance the effect of antibiotics through the AcrB target of bacteria. MBX3135 can be used for research of infection and antibiotics .

HY-179373

*UB-MBX-46*	P2X Receptor	Cardiovascular Disease Neurological Disease Cancer
UB-MBX-46 is a potent and selective P2X7 receptor antagonist with IC₅₀s of 0.514 nM (hP2X7R), 40.6 nM (rP2X7R), and 4.52 nM (mP2X7R), respectively. UB-MBX-46 interacts with the classical allosteric pocket of the human P2X7 receptor. UB-MBX-46 can be used for cancer, atherosclerosis, and neurode generation research .

HY-19522B

Seladelpar (lysine) 1 Publications Verification MBX-8025 (lysine); RWJ-800025 (lysine)	PPAR	Metabolic Disease
Seladelpar (MBX-8025) lysine is an orally active, potent and specific PPARδ agonist with an EC₅₀ of 2 nM. Seladelpar lysine shows more than 750-fold and 2500-fold selectivity over the PPARα and PPARγ receptors, respectively. Seladelpar lysine can be used for the study of primary biliary cholangitis .

HY-19522R

Seladelpar (Standard) MBX-8025 (Standard); RWJ-800025 (Standard)	PPAR Reference Standards	Metabolic Disease
Seladelpar (Standard) is the analytical standard of Seladelpar. This product is intended for research and analytical applications. Seladelpar (MBX-8025) is an orally active, potent and specific PPARδ agonist with an EC50 of 2 nM. Seladelpar shows more than 750-fold and 2500-fold selectivity over the PPARα and PPARγ receptors, respectively. Seladelpar can be used for the study of primary biliary cholangitis .

HY-138997

MBX-102 acid	PPAR	Metabolic Disease
MBX-102 acid is a selective partial PPAR-γ agonist. MBX-102 acid binds highly to plasma proteins, mainly serum albumin. MBX-102 acid can be used to study type 2 diabetes .

HY-15291R

MBX-2982 (Standard)	GPR119	Metabolic Disease
MBX-2982 (Standard) is the analytical standard of MBX-2982. This product is intended for research and analytical applications. MBX-2982 is a selective, orally-available G protein-coupled receptor 119 (GPR119) agonist.

HY-129318

MBX-1066	Bacterial	Infection
MBX 1066 is a potent antibacterial agent. MBX 1066 shows inhibition for Mycobacterium tuberculosis. MBX 1066 shows antibacterial activity in mice .

HY-126742

MBX-1162	Bacterial	Others
MBX-1162 is a bisindole compound. In the study of its resistance mechanism in Staphylococcus aureus, it did not show cross-resistance with related compounds and was related to the substrate specificity of MepA and MepR.

HY-14831A

(+)-Arhalofenate (+)-MBX 102; (+)-JNJ 39659100	PPAR	Metabolic Disease
(+)-Arhalofenate ((+)-MBX 102) is the less active enantiomer of Arhalofenate (HY-14831). Arhalofenate is a selective partial agonist of peroxisome proliferator-activated receptor (PPAR)-γ, used for the treatment of type 2 diabetes .

HY-RS03821

DMBX1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
DMBX1 Human Pre-designed siRNA Set A contains three designed siRNAs for DMBX1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

DMBX1 Human Pre-designed siRNA Set A DMBX1 Human Pre-designed siRNA Set A

Cat. No.	상품명	Target	Research Area

HY-P10957

Imapextide MBX 1416	GLP Receptor	Metabolic Disease
Imapextide is a glucagon-like peptide-1 (GLP-1) receptor antagonist that can be used in hypoglycemia research .

HY-P10909

Canvuparatide MBX 2109	Thyroid Hormone Receptor	Endocrinology
Canvuparatide (MBX 2109) is a prodrug for parathyroid hormone (PTH) peptide that releases the bioactive PTH[1-32] peptide agonist that retains a fatty acylated lysine (Lys33) at the C-terminus, thereby extending the halflife of Canvuparatide. Canvuparatide can be used for the symptoms of hypoparathyroidism such as hypocalcemia and hyperphosphatemia .

DMBX1 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
DMBX1 Human Pre-designed siRNA Set A contains three designed siRNAs for DMBX1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

온라인 문의

Your information is safe with us. * Required Fields.

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社重松貿易株式会社
호칭			Country or Region *
고객명 *			회사명 *
Department *
메일주소 *			상품명 *
Cat. No.			Requested quantity *
전화번호 *
비고

온라인 문의

Inquiry Information

상품명:
Cat. No.:
수량:
MCE Japan Authorized Agent:

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

We use cookies

MedChemExpress values your privacy and your trust is important to us. We use cookies to enhance your website experience. Some cookies are necessary to run the website. Privacy and Cookie Policy

Name
이메일 *

	Sorry, but the email address you supplied was invalid.