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Results for "

Apaf-1

" in MedChemExpress (MCE) Product Catalog:

6

Inhibitors & Agonists

4

Recombinant Proteins

2

Antibodies

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Cat. No. Compare Product Name Species Source
  • HY-P700502
    APAF1 Protein, Human (P. pastoris, His)

    Apaf 1; Apaf-1; Apaf_HUMAN; Apaf1; Apoptotic peptidase activating factor 1; Apoptotic protease activating factor 1; Apoptotic protease activating factor; Apoptotic protease-activating factor 1; CED 4; CED4; KIAA0413

    		 Human P. pastoris
    APAF1 Protein, a pivotal apoptosome component, orchestrates cytochrome c-dependent activation of pro-caspase-9, initiating caspase-3 activation and apoptosis. Forming an apoptosome ring with cytochrome c and dATP, APAF1 interacts with pro-caspase-9, releasing mature caspase-9. Pro-caspase-3 joins the complex, activating caspase-3. Notably, APAF1 isoform 6 is less effective in inducing apoptosis. APAF1 interacts with APIP, NAIP/BIRC1, and CIAO2A, contributing to its multifaceted role in apoptotic regulation. APAF1 Protein, Human (P. pastoris, His) is the recombinant human-derived APAF1 protein, expressed by P. pastoris, with N-6*His labeled tag. The total length of APAF1 Protein, Human (P. pastoris, His) is 312 a.a., with molecular weight of 37.4 kDa.
  • HY-P702005
    NLRP6 Protein, Human (Sf9)

    NLRP6; NACHT; LRR and PYD domains-containing protein 6; Angiotensin II/vasopressin receptor; PYRIN-containing Apaf1-like protein 5

    		 Human Sf9 insect cells
    The NLRP6 protein serves as the central sensor of the NLRP6 inflammasome, driving inflammasome activation in response to various pathogen-related signals. It recognizes specific pathogen- and damage-associated signals, such as lipoteichoic acid (LTA) and double-stranded RNA (dsRNA), initiating liquid-liquid phase separation (LLPS) to form complexes. NLRP6 Protein, Human (Sf9) is the recombinant human-derived NLRP6 protein, expressed by Sf9 insect cells , with tag free. The total length of NLRP6 Protein, Human (Sf9) is 892 a.a., .
  • HY-P702813
    NLRP6 Protein, Human (Sf9, His, MBP)

    NLRP6; NACHT; LRR and PYD domains-containing protein 6; Angiotensin II/vasopressin receptor; PYRIN-containing Apaf1-like protein 5

    		 Human Sf9 insect cells
  • HY-P71598
    NLRP3 Protein, Mouse (His-SUMO)
    1 Publications Verification

    Nlrp3; Cias1; Mmig1; Nalp3; Pypaf1; NACHT; LRR and PYD domains-containing protein 3; Cold autoinflammatory syndrome 1 protein homolog; Cryopyrin; Mast cell maturation-associated-inducible protein 1; PYRIN-containing Apaf1-like protein 1

    		 Mouse E. coli
    The NLRP3 protein acts as a sensor in the NLRP3 inflammasome, which is activated in response to membrane defects caused by pathogens or damage signals. It assembles the inflammasome complex, including NLRP3, CASP1, and PYCARD/ASC. NLRP3 Protein, Mouse (His-SUMO) is the recombinant mouse-derived NLRP3 protein, expressed by E. coli , with N-SUMO, N-6*His labeled tag. The total length of NLRP3 Protein, Mouse (His-SUMO) is 153 a.a., with molecular weight of ~35 kDa.

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