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Isoforms Recommended:	Aurora C

Results for "

Aurora+C

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Aurora Kinase (6) Apoptosis (2) Autophagy (1) PDGFR (2) Small Interfering RNA (siRNA) (1) VEGFR (2)
By Research Areas:	Cancer (5)
Oligonucleotides:	Human Pre-designed siRNA Sets (1) siRNAs (1)

Inhibitors & Agonists

Fluorescent Dyes

Biochemical Assay Reagents

Recombinant Proteins

Antibodies

Oligonucleotides

GMP Molecules

Targets Recommended: Aurora Kinase

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-14711

Reversine 15+ Cited Publications	Aurora Kinase Autophagy	Cancer
Reversine is a novel class of ATP-competitive Aurora kinase inhibitor with IC₅₀s of 400, 500 and 400 nM for Aurora A, Aurora B and *Aurora C*, respectively.

HY-70044

GSK-1070916 5 Publications Verification GSK-1070916A	Aurora Kinase Apoptosis	Cancer
GSK-1070916 is a potent and selective ATP-competitive inhibitor of aurora B and *aurora C* with K_is of 0.38 and 1.5 nM, respectively, and is >250- fold selective over Aurora A.

HY-16018A

Ilorasertib hydrochloride ABT-348 hydrochloride	Aurora Kinase PDGFR VEGFR	Cancer
Ilorasertib (ABT-348) hydrochloride is a potent, orally active and ATP-competitive *aurora* inhibitor with IC₅₀s of116, 5, 1 nM for aurora A, aurora B, aurora C, respectively. Ilorasertib hydrochloride also is a potent VEGF, PDGF inhibitor. Ilorasertib hydrochloride has the potential for the research of acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS) .

HY-16018

Ilorasertib ABT-348	Aurora Kinase VEGFR PDGFR	Cancer
Ilorasertib (ABT-348) is a potent, orally active and ATP-competitive *aurora* inhibitor with IC₅₀s of116, 5, 1 nM for aurora A, aurora B, aurora C, respectively. Ilorasertib also is a potent VEGF, PDGF inhibitor. Ilorasertib has the potential for the research of acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS) .

HY-RS01273

AURKC Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA) Aurora Kinase	Others
AURKC Human Pre-designed siRNA Set A contains three designed siRNAs for AURKC gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

AURKC Human Pre-designed siRNA Set A AURKC Human Pre-designed siRNA Set A

HY-70044G

GSK-1070916 GSK-1070916A	Apoptosis Aurora Kinase	Cancer
GSK-1070916 (GMP) is GSK-1070916 (HY-70044) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. GSK-1070916 is a potent and selective ATP-competitive inhibitor of aurora B and *aurora C* with K_is of 0.38 and 1.5 nM, respectively, and is >250- fold selective over Aurora A .

Cat. No.	Product Name	Type

HY-70044G

GSK-1070916 GSK-1070916A	Fluorescent Dyes
GSK-1070916 (GMP) is GSK-1070916 (HY-70044) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. GSK-1070916 is a potent and selective ATP-competitive inhibitor of aurora B and *aurora C* with K_is of 0.38 and 1.5 nM, respectively, and is >250- fold selective over Aurora A .

Cat. No.	Product Name	Type

HY-70044G

GSK-1070916 GSK-1070916A	Biochemical Assay Reagents
GSK-1070916 (GMP) is GSK-1070916 (HY-70044) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. GSK-1070916 is a potent and selective ATP-competitive inhibitor of aurora B and *aurora C* with K_is of 0.38 and 1.5 nM, respectively, and is >250- fold selective over Aurora A .

Species:	Human (2)
Tag:	His (1) Strep (1) GST (2)
Source:	sf9 insect cells (1) Sf9 insect cells (1)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P705736

	AURC-INCENP Protein, Human (Active, sf9, GST, His-StrepII) AURC-INCENP complex; Aurora kinase C; Serine/threonine-protein kinase aurora-C; Serine/threonine-protein kinase 13; AIE2; AIK3; AIRK3; ARK3; STK13; Inner centromere protein	Human	sf9 insect cells

HY-P701710

	AURC Protein, Human (sf9, GST) AURKC; Aurora kinase C; Aurora 3; Aurora/IPL1-related kinase 3; ARK-3; Aurora-related kinase 3; Aurora/IPL1/Eg2 protein 2; Serine/threonine-protein kinase 13; Serine/threonine-protein kinase aurora-C	Human	Sf9 insect cells
	AURC is a key serine/threonine protein kinase that plays a critical regulatory role in mitosis as part of the chromosomal passenger complex (CPC), ensuring accurate chromosome alignment and segregation. It contributes to chromatin-induced microtubule stabilization and spindle assembly. AURC Protein, Human (sf9, GST) is the recombinant human-derived AURC protein, expressed by sf9 insect cells , with N-GST labeled tag.

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Host:	Mouse (2) Rabbit (1)
Reactivity:	Human (3)
Application:	ICC/IF (3) WB (3) ELISA (1)
Isotype:	IgG, Kappa (1) IgG1 (2)
Conjugation:	Non-conjugated (3)
Clonality:	Monoclonal (2) Recombinant (1)
Modification:	Unmodified (2)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P88440

	AURKC Antibody (YA8124) AIE2; AIK3; ARK3; AurC; aurora-C; HEL-S-90; SPGF5; STK13	WB, ICC/IF	Human
	AURKC Antibody (YA8124) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to AURKC.

HY-P88440A

	AURKC Antibody (YA8124)(PBS only) AIE2; AIK3; ARK3; AurC; aurora-C; HEL-S-90; SPGF5; STK13	WB, ICC/IF	Human
	AURKC Antibody (YA8124) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to AURKC.

HY-P87762

	Aurora C Antibody (YA7447)	WB, ICC/IF, ELISA	Human
	Aurora C Antibody (YA7447) is a Rabbit-derived and non-conjugated IgG, Kappa monoclonal antibody, targeting to Aurora C.

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Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote

Cat. No.	Product Name		Classification

HY-RS01273

AURKC Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
AURKC Human Pre-designed siRNA Set A contains three designed siRNAs for AURKC gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

Targets Recommended: Aurora Kinase

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-70044G

GSK-1070916 GSK-1070916A	Apoptosis Aurora Kinase	Cancer
GSK-1070916 (GMP) is GSK-1070916 (HY-70044) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. GSK-1070916 is a potent and selective ATP-competitive inhibitor of aurora B and *aurora C* with K_is of 0.38 and 1.5 nM, respectively, and is >250- fold selective over Aurora A .

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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