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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
8 Results for "
BPTF bromodomain
" in MedChemExpress (MCE) Product Catalog:
Products (8)
8 Results for "BPTF bromodomain" in MCE Product Catalog:
Cat. No.: HY-141703A
Purity: ≥97.0%
Target:
Research Areas:
DC-BPi-11 hydrochloride is an inhibitor of bromodomain PHD finger transcription factor (BPTF), with an IC50 value of 698 nM. DC-BPi-11 hydrochloride shows remarkable inhibition against leukemia cell proliferation .
Cat. No.: HY-126299
CAS No.: 2662454-54-6
Target:
Research Areas:
NVS-BPTF-1, a chemical probe, is a selective inhibitor for bromodomain and PHD finger containing transcription factor (BPTF), with KD of 71 nM .
Cat. No.: HY-141703
CAS No.: 2758411-61-7
Target:
Research Areas:
DC-BPi-11 is an inhibitor of bromodomain PHD finger transcription factor (BPTF), with an IC50 value of 698 nM. DC-BPi-11 shows remarkable inhibition against leukemia cell proliferation .
Cat. No.: HY-145431
CAS No.: 2359618-49-6
Target:
Research Areas:
(S)-GSK1379725A (compound AU1) is a selective bromodomain and PHD finger containing transcription factor (BPTF) bromodomain inhibitor with a Kd of 2.8 μM. (S)-GSK1379725A shows to be selective for BPTF over BRD4 bromodomain. (S)-GSK1379725A shows antimalarial activity .
Cat. No.: HY-111575
CAS No.: 723245-31-6
Target:
Research Areas:
DCB29 is a selective inhibitor of the BPTF bromodomain, with an IC50 value of 13.2 μM. DCB29 can be used for the study of the BPTF-related diseases (such as bladder cancer, colorectal cancer, melanoma, leukemia, and other cancers) .
Cat. No.: HY-P701611
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: BPTF; Nucleosome-Remodeling Factor Subunit BPTF; Prev. FALZ; bromodomain And PHD Domain Transcription Factor; FAC1; Nucleosome Remodeling Factor, Large Subunit; Fetal Alzheimer Antigen; Fetal Alz-50 Reactive Clone 1; NURF301; BPTF Protein; bromodomain And
Species:
Human
Source:
E. coli
Cat. No.: HY-P701612
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: BPTF; Nucleosome-Remodeling Factor Subunit BPTF; Prev. FALZ; bromodomain And PHD Domain Transcription Factor; FAC1; Nucleosome Remodeling Factor, Large Subunit; Fetal Alzheimer Antigen; Fetal Alz-50 Reactive Clone 1; NURF301; BPTF Protein; bromodomain And
Species:
Human
Source:
E. coli
Cat. No.: HY-155891
CAS No.: 874594-37-3
Target:
Research Areas:
BET-IN-18 (Compound 3) is a pan-BET bromodomain small-molecule inhibitor, with Ki values of 0.69 μM and 0.37 μM, and Kd values of 1.6 μM and 8.4 μM against BrdT (1) and Brd4 (1) bromodomains, respectively. BET-IN-18 potently and competitively inhibits the binding of the known BET inhibitor (+)-JQ1 (HY-13030) to Brd4 (1) and BrdT (1), with IC50 values of 1.0 μM and 2.3 μM, respectively. BET-IN-18 also competitively inhibits the binding of acetylated histone substrates to Brd4 (1) (IC50 = 0.90 μM). BET-IN-18 can be used in the research of multiple myeloma .
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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
