Search Result

Results for "

CME

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Antibiotic (1) Apoptosis (1) Biochemical Assay Reagents (1) COX (1) Dynamin (3) HIV (1) Influenza Virus (1) Isotope-Labeled Compounds (1)
By Research Areas:	Cancer (2) Infection (3) Inflammation/Immunology (1) Metabolic Disease (1) Neurological Disease (3)

Inhibitors & Agonists

Biochemical Assay Reagents

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-115604

Pitstop 2 5+ Cited Publications	Apoptosis	Cancer
Pitstop 2 is a clathrin inhibitor which inhibits clathrin-mediated endocytosis (CME) by associating with the terminal domain of clathrin. Pitstop 2 has the potential for anti-cancer research .

HY-119764

Ikarugamycin

2 Publications Verification

Antibiotic Others

Ikarugamycin is an antibiotic and a inhibitor of clathrin-mediated endocytosis (CME) .

Ikarugamycin 2 Publications Verification	Antibiotic	Others
Ikarugamycin is an antibiotic and a inhibitor of clathrin-mediated endocytosis (CME) .

HY-145080

Dynole 2−24	Dynamin	Neurological Disease
Dynole 2−24 is an indole-based dynamin GTPase inhibitor (IC₅₀=0.56 μM for dynamin I). Dynole 2−24 is nontoxic and shows increased potency against dynamin I and II in vitro and in cells (IC_₅₀(CME)=1.9 μM). Dynole 2−24 also shows 4.4-fold selectivity for dynamin I. Dynole 2−24 is active in-cell inhibitor of clathrin-mediated endocytosis . CME: Clathrin mediated endocytosis

HY-W013741

CME-carbodiimide	Biochemical Assay Reagents	Others
CME-carbodiimide is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-B1888AS

Bromfenac-d4 sodium	Isotope-Labeled Compounds COX	Inflammation/Immunology
Bromfenac-d₄ (sodium) is deuterium labeled Bromfenac (sodium). Bromfenac sodium is a potent and orally active inhibitor of COX, with IC50s of 5.56 and 7.45 nM for COX-1 and COX-2, respectively. Bromfenac sodium is a brominated non-steroidal anti-inflammatory/analgesic agent (NSAID), and it is commonly used for the research of postoperative inflammation and pain following cataract surgery, and pseudophakic cystoid macular edema (CME)[1][2].

HY-158097

IAV-IN-2	Influenza Virus	Infection
IAV-IN-2 (Compound MC-22) inhibits for Influenza A Virus (IAV) through blocking the entry of IAV into host cell via clathrin-mediated endocytosis (CME) .

HY-152217

Clathrin-IN-2	Dynamin	Neurological Disease Metabolic Disease Cancer
Clathrin-IN-2 is potent inhibitor of clathrin mediated endocytosis (CME) with an IC₅₀ value of 2.3 μM. Clathrin-IN-2 also has inhibitiory for dyn I GTPase with an IC₅₀ value of 7.7 μM .

HY-145081

Pitnot-2

Others Infection

Pitnot-2 is an inactive analog of clathrin inhibitor Pitstop 2. Pitnot-2 can be used as negative control .

Pitnot-2	Others	Infection
Pitnot-2 is an inactive analog of clathrin inhibitor Pitstop 2. Pitnot-2 can be used as negative control .

HY-152216

Dynamin IN-2	Dynamin	Neurological Disease
Dynamin IN-2 (compound 43), a Wiskostatin (HY-12534) analogue, is a potent dynamin inhibitor, with an IC₅₀ of 1.0 μM for dynamin I GTPase. Dynamin IN-2 also blocks clathrin mediated endocytosis (CME), with an IC₅₀ of 9.5 μM .

HY-102068

Clathrin-IN-1	HIV	Infection
Clathrin-IN-1 is a selective clathrin-mediated endocytosis (CME) inhibitor. Clathrin-IN-1 selectively inhibits amphiphysin association of clathrin terminal domain (TD) with an IC₅₀ value of 12 μM. Clathrin-IN-1 acutely interferes with receptor-mediated endocytosis, entry of HIV, and synaptic vesicle recycling .

HY-131683

ES9-17	Others	Others
ES9-17 is an analog of ES9 (endosidin9), which is an inhibitor of clathrin heavy chain (CHC). ES9-17 is an inhibitor of clathrin-mediated endocytosis (CME), a major route for internalization of plasma membrane proteins and molecules from the extracellular environment in plants. ES9-17 inhibits the uptake of transferrin and FM4-64. ES9-17 also inhibits root growth of Arabidopsis seedings .

CME-carbodiimide	Biochemical Assay Reagents
CME-carbodiimide is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-119764

Ikarugamycin 2 Publications Verification	Structural Classification Microorganisms Classification of Application Fields Antibiotics Source classification Other Diseases Antibacterial Disease Research Disease Research Fields Other Antibiotics	Antibiotic
Ikarugamycin is an antibiotic and a inhibitor of clathrin-mediated endocytosis (CME) .

Cat. No.	Product Name	Chemical Structure

HY-B1888AS

Bromfenac-d4 sodium
Bromfenac-d₄ (sodium) is deuterium labeled Bromfenac (sodium). Bromfenac sodium is a potent and orally active inhibitor of COX, with IC50s of 5.56 and 7.45 nM for COX-1 and COX-2, respectively. Bromfenac sodium is a brominated non-steroidal anti-inflammatory/analgesic agent (NSAID), and it is commonly used for the research of postoperative inflammation and pain following cataract surgery, and pseudophakic cystoid macular edema (CME)[1][2].

Bromfenac-d4 sodium

Bromfenac-d₄ (sodium) is deuterium labeled Bromfenac (sodium). Bromfenac sodium is a potent and orally active inhibitor of COX, with IC50s of 5.56 and 7.45 nM for COX-1 and COX-2, respectively. Bromfenac sodium is a brominated non-steroidal anti-inflammatory/analgesic agent (NSAID), and it is commonly used for the research of postoperative inflammation and pain following cataract surgery, and pseudophakic cystoid macular edema (CME)[1][2].

Inquiry Online

Your information is safe with us. * Required Fields.

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社
Salutation			Country or Region *
Applicant Name *			Organization Name *
Department *
Email Address *			Product Name *
Cat. No.			Requested quantity *
Phone Number *
Remarks