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  3. Drug Derivative
  4. Pitnot-2

Pitnot-2 is an inactive analog of clathrin inhibitor Pitstop 2. Pitnot-2 can be used as negative control.

For research use only. We do not sell to patients.

Pitnot-2

Pitnot-2 Chemical Structure

CAS No. : 1576239-29-6

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Based on 1 publication(s) in Google Scholar

Pitnot-2 Related Antibodies

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Description

Pitnot-2 is an inactive analog of clathrin inhibitor Pitstop 2. Pitnot-2 can be used as negative control[1].

Molecular Weight

409.30

Formula

C20H13BrN2OS
CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

BrC(C=C1)=CC=C1/C=C2SC(NC3=CC=CC4=C3C=CC=C4)=NC\2=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (122.16 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.4432 mL 12.2160 mL 24.4320 mL
5 mM 0.4886 mL 2.4432 mL 4.8864 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.4432 mL 12.2160 mL 24.4320 mL 61.0799 mL
5 mM 0.4886 mL 2.4432 mL 4.8864 mL 12.2160 mL
10 mM 0.2443 mL 1.2216 mL 2.4432 mL 6.1080 mL
15 mM 0.1629 mL 0.8144 mL 1.6288 mL 4.0720 mL
20 mM 0.1222 mL 0.6108 mL 1.2216 mL 3.0540 mL
25 mM 0.0977 mL 0.4886 mL 0.9773 mL 2.4432 mL
30 mM 0.0814 mL 0.4072 mL 0.8144 mL 2.0360 mL
40 mM 0.0611 mL 0.3054 mL 0.6108 mL 1.5270 mL
50 mM 0.0489 mL 0.2443 mL 0.4886 mL 1.2216 mL
60 mM 0.0407 mL 0.2036 mL 0.4072 mL 1.0180 mL
80 mM 0.0305 mL 0.1527 mL 0.3054 mL 0.7635 mL
100 mM 0.0244 mL 0.1222 mL 0.2443 mL 0.6108 mL
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Pitnot-2 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Pitnot-21576239-29-6Pitnot2Pitnot 2Drug DerivativeDrug derivativeclathrininactivecontrolnegativeCMEHIVInhibitorinhibitorinhibit

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