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Results for "

HEK-AT1 cells

" in MedChemExpress (MCE) Product Catalog:

8

Inhibitors & Agonists

2

Natural
Products

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-19608
    GSK1016790A
    Maximum Cited Publications
    38 Publications Verification

    		 TRP Channel Calcium Channel Cardiovascular Disease Metabolic Disease
    GSK1016790A is a potent and selective transient receptor potential vanilloid 4 (TRPV4) channel agonist. GSK1016790A can elicit Ca 2+ influx and elevate intracellular Ca 2+ in HEK cells .
    GSK1016790A
  • HY-101560
    Linrodostat
    5+ Cited Publications

    BMS-986205; ONO-7701

    		 Indoleamine 2,3-Dioxygenase (IDO) Cancer
    Linrodostat (BMS-986205) is a selective and irreversible indoleamine 2,3-dioxygenase 1 (IDO1) inhibitor with an IC50 value of 1.1 nM in IDO1-HEK293 cells. Linrodostat is well tolerated with potent pharmacodynamic activity in advanced cancers .
    Linrodostat
  • HY-115675
    NC03

    		PI4K Others
    NC03 is a PI4K2A inhibitor and reducing agent. NC03 inhibits the activity of PI4K2A, thereby reducing the production of PI4P in the cellular compartments where PI4K2A functions. NC03 rapidly induces a decrease in PI4P pools in the Golgi and endosomal compartments. NC03 reduces PI4P production in Rab7-positive late endosomes .
    NC03
  • HY-101560A
    Linrodostat mesylate

    BMS-986205 mesylATe; ONO-7701 mesylATe

    		 Indoleamine 2,3-Dioxygenase (IDO) Cancer
    Linrodostat (BMS-986205) mesylate is a selective irreversible inhibitor of indoleamine 2,3-dioxygenase 1 (IDO1), which effectively inhibits IDO1-HEK293 mesylate cells with an IC50 value of 1.1 nM. Linrodostat mesylate demonstrates good pharmacological activity in advanced cancer .
    Linrodostat mesylate
  • HY-N12008
    OAT1/3-IN-2

    		OAT Metabolic Disease
    OAT1/3-IN-2 (compound 8) is a dual inhibitor of OAT1 and OAT3. OAT1/3-IN-2 can reverse the toxicity of Cys-Hg on HEK-OAT1 cells (10 μM) and has a potential protective effect on the kidneys. OAT1/3-IN-2 can be used to study mercury-induced kidney damage .
    OAT1/3-IN-2
  • HY-N12007
    OAT1/3-IN-1

    		OAT Metabolic Disease
    OAT1/3-IN-1 (compound 7) is a dual inhibitor of OAT1 and OAT3. OAT1/3-IN-1 can reverse the toxicity of Cys-Hg on HEK-OAT1 cells (10 μM) and has a potential protective effect on the kidneys. OAT1/3-IN-1 can be used to study mercury-induced kidney damage .
    OAT1/3-IN-1
  • HY-W246010
    α,α-DiBn-DL-Gly

    Dibenzylglycine

    		 Amino acid Transporter Others
    α,α-DiBn-DL-Gly (Dibenzylglycine) is an achiral α-substituted phenylalanine derivative, non-substrate weak inhibitor of LAT1 (L-type amino acid transporter 1). α,α-DiBn-DL-Gly does not stimulate efflux of-Gabapentin from preloaded HEK-hLAT1 cells. α,α-DiBn-DL-Gly shows minimal inhibition of-Gabapentin (HY-A0057) uptake into HEK-hLAT1 cells .
    α,α-DiBn-DL-Gly
  • HY-101560R
    Linrodostat (Standard)

    BMS-986205 (Standard); ONO-7701 (Standard)

    		 Indoleamine 2,3-Dioxygenase (IDO) Reference Standards Cancer
    Linrodostat (Standard) is the analytical standard of Linrodostat (HY-101560). This product is intended for research and analytical applications. Linrodostat (BMS-986205) is a selective and irreversible indoleamine 2,3-dioxygenase 1 (IDO1) inhibitor with an IC50 value of 1.1 nM in IDO1-HEK293 cells. Linrodostat is well tolerated with potent pharmacodynamic activity in advanced cancers .
    Linrodostat (Standard)

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