α,α-DiBn-DL-Gly
α,α-DiBn-DL-Gly (Dibenzylglycine) is an achiral α-substituted phenylalanine derivative, non-substrate weak inhibitor of LAT1 (L-type amino acid transporter 1). α,α-DiBn-DL-Gly does not stimulate efflux of-Gabapentin from preloaded HEK-hLAT1 cells. α,α-DiBn-DL-Gly shows minimal inhibition of-Gabapentin (HY-A0057) uptake into HEK-hLAT1 cells.
For research use only. We do not sell to patients.
- CAS No.: 6278-96-2
- Formula: C16H17NO2
- Molecular Weight:255.31
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
α,α-DiBn-DL-Gly (200 μM; 3 min) does not act as a LAT1 substrate in induced TREx HEK-hLAT1 cells, as evidenced by its 23% relative exchange efflux rate[1].
α,α-DiBn-DL-Gly (200 μM; 3 min) shows minimal inhibitory activity against LAT1 in induced TREx HEK-hLAT1 cells, as evidenced by its 11% uptake inhibition of [3H]-gabapentin at 200 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 6278-96-2
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Molecular Weight 255.31
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Formula C16H17NO2
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SMILES
O=C(C(CC1=CC=CC=C1)(CC2=CC=CC=C2)N)O
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Synonyms
Dibenzylglycine
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)