1. Metabolic Enzyme/Protease
  2. Indoleamine 2,3-Dioxygenase (IDO)

BMS-986205 

Cat. No.: HY-101560 Purity: 98.70%
Handling Instructions

BMS-986205 is a selective indoleamine 2,3-dioxygenase 1 (IDO1) inhibitor.

For research use only. We do not sell to patients.

BMS-986205 Chemical Structure

BMS-986205 Chemical Structure

CAS No. : 1923833-60-6

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 172 In-stock
Estimated Time of Arrival: December 31
5 mg USD 156 In-stock
Estimated Time of Arrival: December 31
10 mg USD 288 In-stock
Estimated Time of Arrival: December 31
25 mg USD 576 In-stock
Estimated Time of Arrival: December 31
50 mg USD 828 In-stock
Estimated Time of Arrival: December 31
100 mg   Get quote  
200 mg   Get quote  

* Please select Quantity before adding items.

Customer Review

View All Indoleamine 2,3-Dioxygenase (IDO) Isoform Specific Products:

  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

BMS-986205 is a selective indoleamine 2,3-dioxygenase 1 (IDO1) inhibitor.

IC50 & Target[1]

IDO1

 

Clinical Trial
Solvent & Solubility
In Vitro: 

DMSO : ≥ 90 mg/mL (219.03 mM)

H2O : < 0.1 mg/mL (insoluble)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.4336 mL 12.1681 mL 24.3362 mL
5 mM 0.4867 mL 2.4336 mL 4.8672 mL
10 mM 0.2434 mL 1.2168 mL 2.4336 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.08 mg/mL (5.06 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: 2.08 mg/mL (5.06 mM); Suspended solution; Need ultrasonic

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.08 mg/mL (5.06 mM); Clear solution

References
Molecular Weight

410.91

Formula

C₂₄H₂₄ClFN₂O

CAS No.

1923833-60-6

SMILES

O=C(NC1=CC=C(Cl)C=C1)[[email protected]](C)[[email protected]@](CC2)([H])CC[[email protected]]2C3=CC=NC4=C3C=C(F)C=C4

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

Purity: 98.70%

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
BMS-986205
Cat. No.:
HY-101560
Quantity:

BMS-986205

Cat. No.: HY-101560