1. Metabolic Enzyme/Protease
  2. Indoleamine 2,3-Dioxygenase (IDO)
  3. Linrodostat

Linrodostat (Synonyms: BMS-986205; ONO-7701)

Cat. No.: HY-101560 Purity: 99.92%
Handling Instructions

Linrodostat (BMS-986205; ONO-7701) is a selective indoleamine 2,3-dioxygenase 1 (IDO1) inhibitor.

For research use only. We do not sell to patients.

Linrodostat Chemical Structure

Linrodostat Chemical Structure

CAS No. : 1923833-60-6

Size Price Stock Quantity
Free Sample (0.5-1 mg)   Apply now  
10 mM * 1 mL in DMSO USD 172 In-stock
Estimated Time of Arrival: December 31
5 mg USD 156 In-stock
Estimated Time of Arrival: December 31
10 mg USD 288 In-stock
Estimated Time of Arrival: December 31
25 mg USD 576 In-stock
Estimated Time of Arrival: December 31
50 mg USD 828 In-stock
Estimated Time of Arrival: December 31
100 mg   Get quote  
200 mg   Get quote  

* Please select Quantity before adding items.

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Based on 1 publication(s) in Google Scholar

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View All Indoleamine 2,3-Dioxygenase (IDO) Isoform Specific Products:

  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

Linrodostat (BMS-986205; ONO-7701) is a selective indoleamine 2,3-dioxygenase 1 (IDO1) inhibitor.

IC50 & Target[1]

IDO1

 

Clinical Trial
Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (121.68 mM; Need ultrasonic)

H2O : < 0.1 mg/mL (insoluble)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.4336 mL 12.1681 mL 24.3362 mL
5 mM 0.4867 mL 2.4336 mL 4.8672 mL
10 mM 0.2434 mL 1.2168 mL 2.4336 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.08 mg/mL (5.06 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: 2.08 mg/mL (5.06 mM); Suspended solution; Need ultrasonic

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.08 mg/mL (5.06 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
Molecular Weight

410.91

Formula

C₂₄H₂₄ClFN₂O

CAS No.

1923833-60-6

SMILES

O=C(NC1=CC=C(Cl)C=C1)[[email protected]](C)[[email protected]@](CC2)([H])CC[[email protected]]2C3=CC=NC4=C3C=C(F)C=C4

Shipping

Room temperature in continental US; may vary elsewhere

Purity: 99.92%

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
Linrodostat
Cat. No.:
HY-101560
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Linrodostat

Cat. No.: HY-101560