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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
13 Results for "
Inositol triphosphate receptor
" in MedChemExpress (MCE) Product Catalog:
Products (13)
13 Results for "Inositol triphosphate receptor" in MCE Product Catalog:
81
Target:
Research Areas:
2-Aminoethyl diphenylborinate (2-APB) is a cell-permeable inhibitor of Inositol triphosphate receptor (IP3R). 2-Aminoethyl diphenylborinate also inhibits the store-operated Ca 2+ (SOC) channel and activates some TRP channels (V1, V2 and V3). Additionally, 2-Aminoethyl diphenylborinate has inhibitory effects on vasospasm. At high concentrations, it exhibits specific anti-inflammatory and antioxidant effects in neural tissue .
2
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Strontium Ranelate (S12911) is an antiosteoporotic agent that acts by reducing bone resorption and promoting bone formation, thereby inducing a positive bone balance. Strontium Ranelate can also activate the calcium-sensing receptor (CaSR) in non skeletal cells, resulting in the activation of inositol 1, 4, 5-triphosphate production and mitogen-activated protein kinase signaling .
Cat. No.: HY-163171
CAS No.: 1214569-31-9
Target:
Research Areas:
ARN 11391 is a selective enhancer of inositol triphosphate receptor type 1 (ITPR1). ARN 11391 can be used in the study of spinocerebellar ataxia .
Cat. No.: HY-175383
Synonyms: Ins(1,2,6)-P3; 1,2,6-IP3
Target:
Research Areas:
D-myo-Inositol-1,2,6-triphosphate (sodium) is one of the members in inositol phosphate family of second messengers that play an important role in transmitting cellular signals. D-myo-Inositol-1,2,6-triphosphate (sodium) can open calcium channels and increase intracellular calcium upon binding to its receptor on the endoplasmic reticulum .
Cat. No.: HY-175070
Synonyms: Ins(2,4,5)P3 sodium salt; 2,4,5-IP3 sodium salt
Target:
Research Areas:
D-myo-Inositol-2,4,5-triphosphate (Ins(2,4,5)P3) (sodium salt) is a second messenger produced in cells by phospholipase C-mediated hydrolysis of phosphatidylinositol-4,5-biphosphate. D-myo-Inositol-2,4,5-triphosphate (sodium salt) can open calcium channels and increase intracellular calcium upon binding to its receptors on the endoplasmic reticulum. D-myo-Inositol-2,4,5-triphosphate (sodium salt) also acts as a partial agonist at rat hepatic IP3 receptors. D-myo-Inositol-2,4,5-triphosphate (sodium salt) can be studied in research on calcium ions signaling pathway .
Cat. No.: HY-17397R
CAS No.: 135459-87-9
Synonyms: Distrontium renelate (Standard); S12911 (Standard)
Target:
Research Areas:
Strontium Ranelate (Standard) is the analytical standard of Strontium Ranelate. This product is intended for research and analytical applications. Strontium Ranelate (S12911) is an antiosteoporotic agent that acts by reducing bone resorption and promoting bone formation, thereby inducing a positive bone balance. Strontium Ranelate can also activate the calcium-sensing receptor (CaSR) in non skeletal cells, resulting in the activation of inositol 1, 4, 5-triphosphate production and mitogen-activated protein kinase signaling .
Cat. No.: HY-137603
CAS No.: 79049-97-1
Synonyms: UTPγS
Target:
Research Areas:
Uridine-5'-O-(3-thiotriphosphate) (UTPγS), a stable analogue of Uridine triphosphate (UTP) (HY-107372), is a potent agonist of the P2Y2 and P2Y4 receptors with increased metabolic stability. Uridine-5'-O-(3-thiotriphosphate) stimulates inositol phosphate formation in human 1321N1 astrocytoma cells stably expressing the phospholipase C-coupled human P2U-purinoceptor (EC50 = 240 nM) .
Cat. No.: HY-181471
CAS No.: 911105-38-9
Target:
Research Areas:
D-myo-Inositol-3,4,5-triphosphate hexasodium is an inositol (HY-B1411) derivative, a subtype-selective IP3 receptor ligand, with Kd values of 31706 nM, 3019 nM and 11145 nM for rat type 1, type 2 and type 3 receptors, respectively .
Cat. No.: HY-P704115
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ITPRIPL1; Inositol 1,4,5-Trisphosphate receptor-Interacting Protein-Like 1; Prev. KIAA1754L; Inositol 1,4,5-triphosphate receptor Interacting Protein-Like 1; D1B; Inositol 1,4,5-triphosphate receptor-Interacting Protein-Like 1; Inositol 1,4,5-Trisphosphat
Species:
Human
Source:
HEK293
Cat. No.: HY-P704730
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: ITPRIPL1; Inositol 1,4,5-Trisphosphate receptor-Interacting Protein-Like 1; Prev. KIAA1754L; Inositol 1,4,5-triphosphate receptor Interacting Protein-Like 1; D1B; Inositol 1,4,5-triphosphate receptor-Interacting Protein-Like 1; Inositol 1,4,5-Trisphosphat
Species:
Human
Source:
HEK293
Cat. No.: HY-P705974
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ITPRIPL1; Inositol 1,4,5-Trisphosphate receptor-Interacting Protein-Like 1; Prev. KIAA1754L; Inositol 1,4,5-triphosphate receptor Interacting Protein-Like 1; D1B; Inositol 1,4,5-triphosphate receptor-Interacting Protein-Like 1; Inositol 1,4,5-Trisphosphat
Species:
Mouse
Source:
HEK293
Cat. No.: HY-137603A
Synonyms: UTPγS tetrasodium
Target:
Research Areas:
Uridine-5'-O-(3-thiotriphosphate) (UTPγS) tetrasodium, a stable analogue of Uridine triphosphate (UTP) (HY-107372), is a potent agonist of the P2Y2 and P2Y4 receptors with increased metabolic stability. Uridine-5'-O-(3-thiotriphosphate) tetrasodium stimulates inositol phosphate formation in human 1321N1 astrocytoma cells stably expressing the phospholipase C-coupled human P2U-purinoceptor (EC50 = 240 nM) .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
