D-myo-Inositol-3,4,5-triphosphate hexasodium 

D-myo-Inositol-3,4,5-triphosphate hexasodium is an inositol (HY-B1411) derivative, a subtype-selective IP₃ receptor ligand, with K_d values of 31706 nM, 3019 nM and 11145 nM for rat type 1, type 2 and type 3 receptors, respectively^[1].

D-myo-Inositol-3,4,5-triphosphate hexasodium binds to recombinant rat type 1, type 2, and type 3 IP₃ receptors expressed in Sf9 cells with lowest affinity for type 1 (K_d = 31706 nM), highest affinity for type 2 (K_d = 3019 nM), and intermediate affinity for type 3 (K_d = 11145 nM), exhibiting subtype selectivity for type 2 receptors^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

486.04

C₆H₁₂Na₃O₁₅P₃

911105-38-9

O[C@@H]1[C@H]([C@@H]([C@H]([C@H]([C@H]1O)O)OP(O)(O[Na])=O)OP(O)(O[Na])=O)OP(O)(O[Na])=O

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Nerou EP, et al. Selective recognition of inositol phosphates by subtypes of the inositol trisphosphate receptor. Biochem J. 2001;355(Pt 1):59-69.  [Content Brief]