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Results for "

Iridium(III) chloride

" in MedChemExpress (MCE) Product Catalog:

10

Inhibitors & Agonists

3

Fluorescent Dyes

1

Biochemical Assay Reagents

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-W021022
    Iridium(III) chloride hydrate

    Iridium trichloride hydrate

    		 Biochemical Assay Reagents Cancer
    Iridium(III) chloride (hydrate) (Iridium trichloride (hydrate)) is a biochemical reagent. Iridium(III) can be used in the research of colon cancer .
    Iridium(III) chloride hydrate
  • HY-W007596
    Tris(2-phenylpyridinato-C2,N)iridium(III)

    Ir(ppy)3; Tris[2-(pyridin-2-yl)phenyl]iridium

    		 Biochemical Assay Reagents Others
    Tris(2-phenylpyridinato-C2,N)iridium(III) (Ir(ppy)3) is an iridium(III) containing organometallic complex, which is used as a phosphorescent light-emitting material. Tris(2-phenylpyridinato-C2,N)iridium(III) exhibits high luminous efficiency and good thermal stability, that can be used in organic optoelectronics, especially in improving the luminescence efficiency and stability of organic light-emitting diodes (OLEDs) .
    Tris(2-phenylpyridinato-C2,N)iridium(III)
  • HY-148365
    NecroIr1

    		Mixed Lineage Kinase RIP kinase CDK Cancer
    NecroIr1 is an iridium(III) complex, serves as necroptosis inducers in Cisplatin (HY-17394)-resistant lung cancer cells (A549R). NecroIr1 selectively accumulates in mitochondria, leading to oxidative stress and loss of mitochondrial membrane potential (MMP). NecroIr1 activates receptor-interacting serine-threonine kinase 3 (RIPK3) and Mixed Lineage Kinase (MLKL), and regulates CDK4 expression .
    NecroIr1
  • HY-148366
    NecroIr2

    		Mixed Lineage Kinase RIP kinase CDK Cancer
    NecroIr2 is an iridium(III) complex, serves as necroptosis inducers in Cisplatin (HY-17394)-resistant lung cancer cells (A549R). NecroIr2 selectively accumulates in mitochondria, leading to oxidative stress and loss of mitochondrial membrane potential (MMP). NecroIr2 activates receptor-interacting serine-threonine kinase 3 (RIPK3) and mixed lineage kinase domain-like pseudokinase (MLKL), and regulates CDK4 expression .
    NecroIr2
  • HY-W034041
    Ir(p-F-ppy)3

    Tris(2-(4-fluorophenyl)pyridine)iridium; Tris[5-fluoro-2-(2-pyridinyl-kN)phenyl-kC]Iridium(III)

    		 Endogenous Metabolite
    Ir(pF-ppy)3 (Tris(2-(4-fluorophenyl)pyridine)iridium) is a compound that catalyzes photoreactions and has excellent photocatalytic activity. Ir(pF-ppy)3 can be used as a catalyst in organic reactions, especially in photocatalytic synthesis. Ir(pF-ppy)3 shows its unique advantages in promoting electron transfer and improving reaction selectivity. Ir(pF-ppy)3 is also used to improve the efficiency of displays and solar cells.
    Ir(p-F-ppy)3
  • HY-162463
    Ir-UA

    		PD-1/PD-L1 Cancer
    Ir-UA is an usnic acid-derived iridium(III) complex that enhances PD-L1 expression and converts "cold tumors" into "hot tumors." Ir-UA stimulates PD-L1 expression by explicitly regulating the PD-L1 transcription factor .
    Ir-UA
  • HY-W075731
    (Ir[dF(F)ppy]2(dCF3))PF6

    		Biochemical Assay Reagents Others
    (Ir[dF (F) ppy]2 (dCF3)) PF6 is a cyclometalated iridium (III) complex that is used in visible light-mediated photocatalytic organic transformations .
    (Ir[dF(F)ppy]2(dCF3))PF6
  • HY-W072530
    [Ir(ppy)2(bpy)]PF6

    		Fluorescent Dye Others
    [Ir (ppy)2 (bpy)]PF6 is a cyclometalated iridium (III) photosensitizer. [Ir (ppy)2 (bpy)]PF6 can be used in homogeneous photocatalytic systems to achieve visible light-induced water splitting for hydrogen production. [Ir (ppy)2 (bpy)]PF6 functions in homogeneous photocatalytic systems for visible light-driven water splitting to produce hydrogen .
    [Ir(ppy)2(bpy)]PF6
  • HY-W034053
    Ir[p-F(Me)ppy]2(dtbbpy)PF6

    		Fluorescent Dye Others
    Ir[p-F (Me) ppy]2 (dtbbpy) PF6 is a cyclometalated iridium (III) complex. Ir[p-F (Me) ppy]2 (dtbbpy) PF6 absorbs visible light (460 nm) to form a long-lived charge-separated excited state. Ir[p-F (Me) ppy]2 (dtbbpy) PF6 is applicable to visible light-mediated photocatalytic organic transformation reactions .
    Ir[p-F(Me)ppy]2(dtbbpy)PF6
  • HY-182066
    Photosensitizer-9

    		PANoptosis Cancer
    Photosensitizer-9 is an iridium (III)-based photosensitizer with anti-melanoma activity. Photosensitizer-9 exhibits significant phototoxicity (IC50=0.98 μM) and an ideal phototoxicity index (PI=3.05). Under light irradiation, Photosensitizer-9 generates large amounts of intracellular •OH in an oxygen-independent manner. Photosensitizer-9 mediates photodynamic therapy under hypoxic conditions and synergistically activates PANoptosis (by upregulating cleaved Caspase-3, GSDMD-N, p-MLKL), ferroptosis (by disrupting the GSH-GPX4-LPO axis), apoptosis, pyroptosis and necroptosis in melanoma cells. Photosensitizer-9 induces immunogenic cell death by promoting the release of damage-associated molecular patterns under hypoxic conditions and increases the maturation rate of dendritic cells. Photosensitizer-9 reduces tumor volume in melanoma-bearing mice. Photosensitizer-9 is applicable to relevant studies on melanoma .
    Photosensitizer-9

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