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L-Homoserine

" in MedChemExpress (MCE) Product Catalog:

32

Inhibitors & Agonists

6

Biochemical Assay Reagents

4

Peptides

2

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1

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-W002292

    Endogenous Metabolite Others
    L-Homoserine is a non - protein amino acid, which is an important biosynthetic intermediate of threonine, methionine and lysine.
    <em>L-Homoserine</em>
  • HY-W015800

    Biochemical Assay Reagents Others
    L-Homoserine lactone hydrochloride is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    <em>L-Homoserine</em> lactone hydrochloride
  • HY-W025723

    N-(Benzyloxycarbonyl)-L-Homoserine

    Others Cancer
    N-Carbobenzoxy-L-homoserine (N-(Benzyloxycarbonyl)-L-homoserine) is L-homoserine with N-Carbobenzoxy protecting group, which can be used as a linker (ADC Linker) for the synthesis of Antibody-Drug Conjugates (ADCs).
    N-Carbobenzoxy-<em>L-homoserine</em>
  • HY-W008113

    Amino Acid Derivatives Others
    Boc-L-Homoserine is a serine derivative .
    Boc-<em>L-Homoserine</em>
  • HY-119543

    Amino Acid Derivatives Others
    O-Succinyl-L-homoserine is a homoserine derivative. O-Succinyl-L-homoserine is an intermediate in the biosynthesis of methionine in Escherichia coli and Salmonella typhimurium .
    O-Succinyl-<em>L-homoserine</em>
  • HY-114816

    C4-HSL; N-Butyryl-L-Homoserine lactone

    ADC Linker Bacterial Infection Inflammation/Immunology
    N-Butanoyl-L-homoserine lactone (C4-HSL) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N-Butanoyl-L-homoserine lactone has antibacterial activity and is used in antibacterial biofilm . N-Butanoyl-L-homoserine lactone aptamers blocks qurom sensing and inhibits biofilm formation in Pseudomonas aeruginosa .
    N-Butanoyl-<em>L-homoserine</em> lactone
  • HY-115393A

    Bacterial Infection
    N-Heptanoyl-L-homoserine lactone is a member of N-acyl-homoserine lactone family. N-acyl-homoserine lactones (AHL) can regulate gene expression in gram-negative bacteria, such as Echerichia and Salmonella, and are involved in quorum sensing, cell to cell communication among bacteria.
    N-Heptanoyl-<em>L-homoserine</em> lactone
  • HY-124237A

    Bacterial Infection
    N-octanoyl-L-Homoserine lactone is a small diffusible signaling molecule involved in quorum sensing, thereby controlling gene expression and affecting cellular metabolism. N-octanoyl-L-Homoserine lactone can be used for the infection prevention and regulation of virulence in cystic fibro.
    N-Octanoyl-<em>L-homoserine</em> lactone
  • HY-133684

    Bacterial Infection
    N-Tetradecanoyl-L-homoserine lactone is a short-chained N-acyl homoserine lactone (AHL). Diatoms are frequently found in association with Proteobacteria, many members of which employ cell-to-cell communication via AHLs in aquatic habitats .
    N-Tetradecanoyl-<em>L-homoserine</em> lactone
  • HY-133685

    Bacterial Infection
    N-Hexanoyl-L-homoserine lactone is a short-chained N-acyl homoserine lactone (AHL). Diatoms are frequently found in association with Proteobacteria, many members of which employ cell-to-cell communication via AHLs in aquatic habitats .
    N-Hexanoyl-<em>L-homoserine</em> lactone
  • HY-114773

    Biochemical Assay Reagents Others
    Quorum sensing is a regulatory system used by bacteria to control gene expression in response to increased cell density. This regulatory process manifests itself in a variety of phenotypes, including biofilm formation and virulence factor production. Coordinated gene expression is achieved through the production, release and detection of small diffusible signaling molecules called autoinducers. N-acylated homoserine lactones (AHLs) comprise a class of such autoinducers, each of which generally consists of a fatty acid coupled to a homoserine lactone (HSL). Modulation of bacterial quorum-sensing signaling systems to suppress pathogenesis represents a new approach to antimicrobial research for infectious diseases. AHLs differ in acyl length (C4-C18), C3 substitution (hydrogen, hydroxyl, or oxo group), and the presence or absence of one or more carbon-carbon double bonds in the fatty acid chain. These differences confer signaling specificity through the affinity of the LuxR family of transcriptional regulators. C11-HSL has a rare odd-numbered acyl carbon chain and may be a minor quorum-sensing signaling molecule in Pseudomonas aeruginosa strains.
    N-Undecanoyl-<em>L-homoserine</em> lactone
  • HY-W127393

    Biochemical Assay Reagents Others
    Quorum sensing is a regulatory system used by bacteria to control gene expression in response to increased cell density. This regulatory process manifests itself in a variety of phenotypes, including biofilm formation and virulence factor production. Coordinated gene expression is achieved through the production, release and detection of small diffusible signaling molecules called autoinducers. N-acylated homoserine lactones (AHLs) comprise a class of such autoinducers, each of which generally consists of a fatty acid coupled to a homoserine lactone (HSL). Modulation of bacterial quorum-sensing signaling systems to suppress pathogenesis represents a new approach to antimicrobial research for infectious diseases. AHLs differ in acyl length (C4-C18), C3 substitution (hydrogen, hydroxyl, or oxo group), and the presence or absence of one or more carbon-carbon double bonds in the fatty acid chain. These differences confer signaling specificity through the affinity of the LuxR family of transcriptional regulators. C9-HSL is a rare odd-numbered acyl carbon chain produced by wild-type Erwinia carotovora strain SCC 3193 grown in nutrient-rich Luria-Bertani broth (LB) medium.
    N-Nonanoyl-<em>L-homoserine</em> lactone
  • HY-W127487

    Biochemical Assay Reagents Others
    Quorum sensing is a regulatory system used by bacteria to control gene expression in response to increased cell density. This regulatory process manifests itself in a variety of phenotypes, including biofilm formation and virulence factor production. Coordinated gene expression is achieved through the production, release and detection of small diffusible signaling molecules called autoinducers. N-acylated homoserine lactones (AHLs) comprise a class of such autoinducers, each of which generally consists of a fatty acid coupled to a homoserine lactone (HSL). Modulation of bacterial quorum-sensing signaling systems to suppress pathogenesis represents a new approach to antimicrobial research for infectious diseases. AHLs differ in acyl length (C4-C18), C3 substitution (hydrogen, hydroxyl, or oxo group), and the presence or absence of one or more carbon-carbon double bonds in the fatty acid chain. These differences confer signaling specificity through the affinity of the LuxR family of transcriptional regulators. C18-HSL, one of four lipophilic long acyl side chain AHLs produced by the LuxI AHL synthase homolog SinI, is involved in quorum-sensing signaling in strains of Rhizobium meliloti (a nitrogen-fixing bacterial symbiont of the legume M. sativa) . C18-HSL and other hydrophobic AHLs tend to localize in the relatively lipophilic environment of bacterial cells and cannot diffuse freely across the cell membrane. Long-chain N-acyl homoserine lactones can be exported from cells by efflux pumps, or can be transported between communicating cells by extracellular outer membrane vesicles.
    N-Octadecanoyl-<em>L-homoserine</em> lactone
  • HY-W127610

    Biochemical Assay Reagents Others
    N-hexadecanoyl-L-Homoserine lactone is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    N-hexadecanoyl-<em>L-Homoserine</em> lactone
  • HY-137407

    Bacterial Infection
    N-Phenylacetyl-L-homoserine lactone is a small diffusible signaling molecule that strongly antagonizes or super-activates the quorum sensing of Vibrio fischeri .
    N-Phenylacetyl-<em>L-homoserine</em> lactone
  • HY-W036160

    Amino Acid Derivatives Others
    N-Fmoc-O-ethyl-L-homoserine is an homoserine derivative, can be used in cyclic peptide compounds synthesis, as a reducing reagent .
    N-Fmoc-O-ethyl-<em>L-homoserine</em>
  • HY-120242

    Antibiotic Infection
    N-(3-Oxobutanoyl)-L-homoserine lactone (3-oxo-C4-HSL) is a carbapenem antibiotic biosynthesis autoregulator in Erwinia carotovora ATCC 39048. N-(3-Oxobutanoyl)-L-homoserine lactone induces expression of rhiI in R. leguminosarum .
    N-(3-Oxobutanoyl)-<em>L-homoserine</em> lactone
  • HY-108700

    SOD Infection
    N-3-Oxo-octanoyl-L-homoserine lactone, a quorum-sensing signal, is an Agrobacterium autoinducer .
    N-3-Oxo-octanoyl-<em>L-homoserine</em> lactone
  • HY-114816S

    Isotope-Labeled Compounds ADC Linker Bacterial Infection Inflammation/Immunology
    N-butyryl-L-Homoserine lactone-d5 is the deuterium labeled N-Butanoyl-L-homoserine lactone. N-Butanoyl-L-homoserine lactone (C4-HSL) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N-Butanoyl-L-homoserine lactone has antibacterial activity and is used in antibacterial biofilm[1]. N-Butanoyl-L-homoserine lactone aptamers blocks qurom sensing and inhibits biofilm formation in Pseudomonas aeruginosa[2][3].
    N-butyryl-<em>L-Homoserine</em> lactone-d5
  • HY-141641

    HSL

    Bacterial
    N-(3-Oxopentanoyl)-L-homoserine lactone is an autoinducer, a kind of chemical signal molecule which passively diffuses across the bacterial envelope and accumulates intracellularly at high bacterial densities. It may bind to a protein related to the LuxR protein of V. fischeri and causes cell density-dependent gene expression. N-(3-Oxopentanoyl)-L-homoserine can be used for research of quorum sensing .
    N-(3-Oxopentanoyl)-<em>L-homoserine</em> lactone
  • HY-118697

    C12-HSL

    Others Infection
    N-dodecanoyl-L-Homoserine lactone (C12-HSL) is a quorum sensing (QS) signaling molecule. N-dodecanoyl-L-Homoserine lactone (C12-HSL) aptamers blocks qurom sensing and inhibits biofilm formation in Pseudomonas aeruginosa .
    N-dodecanoyl-<em>L-Homoserine</em> lactone
  • HY-136409

    C10-HSL

    Bacterial Reactive Oxygen Species Infection
    N-decanoyl-L-homoserine lactone (C10-HSL) is a N-acyl-homoserine lactone (AHL) N-decanoyl-L-homoserine lactone can inhibit primary root growth in Arabidopsis. N-decanoyl-L-homoserine lactone triggers a transient and immediate increase in the concentrations of cytosolic free Ca 2+ and reactive oxygen species (ROS), increases the activity of mitogen-activated protein kinase 6 (MPK6), and induces nitric oxide (NO) production in Arabidopsis roots .
    N-Decanoyl-<em>L-homoserine</em> lactone
  • HY-114544A

    OdDHL

    Bacterial Others
    N-3-oxo-dodecanoyl-L-Homoserine lactone (3-oxo-C12-HSL) is a bacterial quorum-sensing signaling molecule produced by P. aeruginosa and strains of the B. cepacia complex .Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density.N-3-oxo-dodecanoyl-L-Homoserine lactone induces the production of IL-8 in 16HBE human bronchial epithelial cells .
    N-3-oxo-dodecanoyl-<em>L-homoserine</em> lactone
  • HY-145462

    Bacterial Infection
    N-cis-octadec-9Z-enoyl-L-Homoserine lactone is a potent inhibitor of AhyI. AhyI (expressing acylhomoserine lactone) is responsible for the biosynthesis of autoinducer-1 (AI-1), commonly referred to as a quorum sensing (QS) signaling molecule, which plays an essential role in bacterial communication. N-cis-octadec-9Z-enoyl-L-Homoserine lactone is a competitive inhibitor of AI-1 biosynthesis .
    N-cis-Octadec-9Z-enoyl-<em>L-homoserine</em> lactone
  • HY-W127486

    Biochemical Assay Reagents Others
    N-3-oxo-hexadec-11Z-enoyl-L-Homoserine lactone is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    N-3-oxo-Hexadec-11Z-enoyl-<em>L-homoserine</em> lactone
  • HY-116536

    oxo-C14-HSL

    Bacterial Infection
    N-3-Oxo-tetradecanoyl-L-homoserine lactone (oxo-C14-HSL) is a rhizobacterial inducer and can improve basic defense against nematodes .
    N-3-Oxo-tetradecanoyl-<em>L-homoserine</em> lactone
  • HY-134560

    3-Oxo-C10-HSL

    Others Inflammation/Immunology
    N-(3-Oxodecanoyl)-L-homoserine lactone (3-Oxo-C10-HSL) is a bacterial quorum sensing signal autoinducer molecule .
    N-(3-Oxodecanoyl)-<em>L-homoserine</em> lactone
  • HY-115399A

    3-Oxo-C16-AHL

    Bacterial Metabolic Disease
    N-3-Oxo-hexadecanoyl-L-Homoserine lactone is a signaling molecule to coordinate group behaviors at high densities in many bacteria. N-3-Oxo-hexadecanoyl-L-Homoserine lactone adsorbs to and promotes the remodeling of lipid membranes in ways that could underpin cell-cell or host-cell interactions .
    N-3-Oxo-hexadecanoyl-<em>L-Homoserine</em> lactone
  • HY-W008806

    OHHL; N-(3-Oxohexanoyl)Homoserine lactone

    Bacterial Infection Inflammation/Immunology
    N-(β-ketocaproyl)-L-Homoserine lactone is a component of quorum regulatory sensing .
    N-(3-Oxohexanoyl)-<em>L-homoserine</em> lactone
  • HY-W048668

    Amino Acid Derivatives Others
    N-(((9H-Fluoren-9-yl)methoxy)carbonyl)-O-trityl-L-homoserine is a serine derivative .
    N-(((9H-Fluoren-9-yl)methoxy)carbonyl)-O-trityl-<em>L-homoserine</em>
  • HY-124286

    C14-9Z-HSL

    Bacterial Inflammation/Immunology
    N-cis-Tetradec-9Z-enoyl-L-homoserine lactone (C14-9Z-HSL) is an autoinducer in C. rodentium, that serves as signal molecule, coordinates the gene expression and behaviors through diffusion into cells of different bacterial species .
    N-cis-Tetradec-9Z-enoyl-<em>L-homoserine</em> lactone
  • HY-145492

    N-(3-Oxo-7Z-tetradecenoyl)-L-Homoserine lactone

    Others Inflammation/Immunology
    Δ7(Z)-C14-HSL (Compound 12) is an immunosuppressive agent that can inhibit the proliferation of mouse splenic cells with an IC50 of 17 μM. Δ7(Z)-C14-HSL can be used for further studying its potential as a molecular mechanism in TNF-R-driven immune diseases, especially autoimmune diseases such as psoriasis, rheumatoid arthritis, and type 1 diabetes .
    Δ7(Z)-C14-HSL

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