N-Decanoyl-L-homoserine lactone
Based on 1 Customer Validation
N-decanoyl-L-homoserine lactone (C10-HSL) is a N-acyl-homoserine lactone (AHL) N-decanoyl-L-homoserine lactone can inhibit primary root growth in Arabidopsis. N-decanoyl-L-homoserine lactone triggers a transient and immediate increase in the concentrations of cytosolic free Ca2+ and reactive oxygen species (ROS), increases the activity of mitogen-activated protein kinase 6 (MPK6), and induces nitric oxide (NO) production in Arabidopsis roots.
For research use only. We do not sell to patients.
- Purity : 98.40%
- CAS No.: 177315-87-6
- Formula: C14H25NO3
- Molecular Weight:255.35
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Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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HY-114816
N-Butanoyl-L-homoserine lactone -
HY-133685
N-Hexanoyl-L-homoserine lactone -
HY-124237A
N-Octanoyl-L-homoserine lactone -
HY-118697
N-dodecanoyl-L-Homoserine lactone -
HY-W008806
N-(3-Oxohexanoyl)-L-homoserine lactone -
HY-133684
N-Tetradecanoyl-L-homoserine lactone -
HY-114544A
N-3-oxo-dodecanoyl-L-homoserine lactone -
HY-108700
N-3-Oxo-octanoyl-L-homoserine lactone -
HY-134560
N-(3-Oxodecanoyl)-L-homoserine lactone -
HY-114816R
N-Butanoyl-L-homoserine lactone (Standard) -
HY-136409R
N-Decanoyl-L-homoserine lactone (Standard) -
HY-116536
N-3-Oxo-tetradecanoyl-L-homoserine lactone
Biological Activity
Description
In Vitro
N-decanoyl-L-homoserine lactone (0-75 µM) causes a reduction in primary root growth and promotes lateral root formationin Arabidopsis[1].
N-decanoyl-L-homoserine lactone (0-30 µM) improves cytosolic Ca2+ concentration in wild-type seedlings[1].
Bacterial signal C10-HSL stimulates spore germination of Galactomyces geotrichum by transboundary interaction[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 177315-87-6
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Appearance Solid
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Molecular Weight 255.35
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Formula C14H25NO3
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Color White to off-white
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SMILES
CCCCCCCCCC(N[C@@H]1C(OCC1)=O)=O
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Synonyms
C10-HSL
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Structure Classification
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Initial Source
Agrobacterium tumefaciens
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
In Vitro:
DMSO : 100 mg/mL (391.62 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
In Vivo:
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: ≥ 2.5 mg/mL (9.79 mM); Clear solution
This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
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%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
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%+
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+%Tween-80 + +
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%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL. * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Purity & Documentation
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Data Sheet (283 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.9162 mL | 19.5810 mL | 39.1619 mL | 97.9048 mL |
| 5 mM | 0.7832 mL | 3.9162 mL | 7.8324 mL | 19.5810 mL | |
| 10 mM | 0.3916 mL | 1.9581 mL | 3.9162 mL | 9.7905 mL | |
| 15 mM | 0.2611 mL | 1.3054 mL | 2.6108 mL | 6.5270 mL | |
| 20 mM | 0.1958 mL | 0.9790 mL | 1.9581 mL | 4.8952 mL | |
| 25 mM | 0.1566 mL | 0.7832 mL | 1.5665 mL | 3.9162 mL | |
| 30 mM | 0.1305 mL | 0.6527 mL | 1.3054 mL | 3.2635 mL | |
| 40 mM | 0.0979 mL | 0.4895 mL | 0.9790 mL | 2.4476 mL | |
| 50 mM | 0.0783 mL | 0.3916 mL | 0.7832 mL | 1.9581 mL | |
| 60 mM | 0.0653 mL | 0.3263 mL | 0.6527 mL | 1.6317 mL | |
| 80 mM | 0.0490 mL | 0.2448 mL | 0.4895 mL | 1.2238 mL | |
| 100 mM | 0.0392 mL | 0.1958 mL | 0.3916 mL | 0.9790 mL |
N-Decanoyl-L-homoserine lactone Related Classifications
HY-136409 Related Classifications
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