N-dodecanoyl-L-Homoserine lactone
Based on 1 publication(s) in Google Scholar
N-dodecanoyl-L-Homoserine lactone (C12-HSL) is a quorum sensing (QS) signaling molecule. N-dodecanoyl-L-Homoserine lactone (C12-HSL) aptamers blocks qurom sensing and inhibits biofilm formation in Pseudomonas aeruginosa.
For research use only. We do not sell to patients.
- Purity : 98.0%
- CAS No.: 137173-46-7
- Formula: C16H29NO3
- Molecular Weight:283.41
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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HY-114816
N-Butanoyl-L-homoserine lactone -
HY-133685
N-Hexanoyl-L-homoserine lactone -
HY-124237A
N-Octanoyl-L-homoserine lactone -
HY-136409
N-Decanoyl-L-homoserine lactone -
HY-118697R
N-Dodecanoyl-L-homoserine lactone (Standard) -
HY-114544A
N-3-oxo-dodecanoyl-L-homoserine lactone -
HY-W008806
N-(3-Oxohexanoyl)-L-homoserine lactone -
HY-108700
N-3-Oxo-octanoyl-L-homoserine lactone -
HY-114816R
N-Butanoyl-L-homoserine lactone (Standard) -
HY-136409R
N-Decanoyl-L-homoserine lactone (Standard) -
HY-133685R
N-Hexanoyl-L-homoserine lactone (Standard) -
HY-124237AR
N-Octanoyl-L-homoserine lactone (Standard)
Publications Citing Use of MedChemExpress (MCE) N-dodecanoyl-L-Homoserine lactone
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Biological Activity
Description
In Vitro
Chemical Information
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CAS No. 137173-46-7
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Appearance Solid
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Molecular Weight 283.41
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Formula C16H29NO3
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Color White to off-white
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SMILES
CCCCCCCCCCCC(N[C@H]1CCOC1=O)=O
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Synonyms
C12-HSL
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Publications (1)
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Journal Impact Factor
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Most Recent
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BMC Infect Dis
Harmine acts as a quorum sensing inhibitor decreasing the virulence and antibiotic resistance of Pseudomonas aeruginosa. [Abstract]2024 Jul 31;24(1):760. PMID: 39085766
Solvent & Solubility
In Vitro:
DMSO : 25 mg/mL (88.21 mM; ultrasonic and warming and heat to 80°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
H2O : < 0.1 mg/mL (insoluble)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (268 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.5285 mL | 17.6423 mL | 35.2846 mL | 88.2114 mL |
| 5 mM | 0.7057 mL | 3.5285 mL | 7.0569 mL | 17.6423 mL | |
| 10 mM | 0.3528 mL | 1.7642 mL | 3.5285 mL | 8.8211 mL | |
| 15 mM | 0.2352 mL | 1.1762 mL | 2.3523 mL | 5.8808 mL | |
| 20 mM | 0.1764 mL | 0.8821 mL | 1.7642 mL | 4.4106 mL | |
| 25 mM | 0.1411 mL | 0.7057 mL | 1.4114 mL | 3.5285 mL | |
| 30 mM | 0.1176 mL | 0.5881 mL | 1.1762 mL | 2.9404 mL | |
| 40 mM | 0.0882 mL | 0.4411 mL | 0.8821 mL | 2.2053 mL | |
| 50 mM | 0.0706 mL | 0.3528 mL | 0.7057 mL | 1.7642 mL | |
| 60 mM | 0.0588 mL | 0.2940 mL | 0.5881 mL | 1.4702 mL | |
| 80 mM | 0.0441 mL | 0.2205 mL | 0.4411 mL | 1.1026 mL |
N-dodecanoyl-L-Homoserine lactone Related Classifications
HY-118697 Related Classifications
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