1. Anti-infection
  2. Bacterial
  3. N-dodecanoyl-L-Homoserine lactone

N-dodecanoyl-L-Homoserine lactone  (Synonyms: C12-HSL)

Cat. No.: HY-118697 Purity: 98.0%
Handling Instructions Technical Support

N-dodecanoyl-L-Homoserine lactone (C12-HSL) is a quorum sensing (QS) signaling molecule. N-dodecanoyl-L-Homoserine lactone (C12-HSL) aptamers blocks qurom sensing and inhibits biofilm formation in Pseudomonas aeruginosa.

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N-dodecanoyl-L-Homoserine lactone

N-dodecanoyl-L-Homoserine lactone 화학구조

CAS No. : 137173-46-7

사이즈 가격 재고 수량
무료 샘플 (0.1 - 0.2 mg)   지금 신청하기  
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
해외재고보유
Solution
10 mM * 1 mL in DMSO 해외재고보유
Solid
5 mg 해외재고보유
10 mg 해외재고보유
25 mg 해외재고보유
50 mg 해외재고보유
100 mg 해외재고보유
200 mg   견적 받기  
500 mg   견적 받기  

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

This product is a controlled substance and not for sale in your territory.

고객리뷰

Based on 1 publication(s) in Google Scholar

Other Forms of N-dodecanoyl-L-Homoserine lactone:

Top Publications Citing Use of Products

1 Publications Citing Use of MCE N-dodecanoyl-L-Homoserine lactone

  • Biological Activity

  • 순도&문서

  • References

  • 고객리뷰

제품 설명

N-dodecanoyl-L-Homoserine lactone (C12-HSL) is a quorum sensing (QS) signaling molecule. N-dodecanoyl-L-Homoserine lactone (C12-HSL) aptamers blocks qurom sensing and inhibits biofilm formation in Pseudomonas aeruginosa[1].

In Vitro

Disruption of cell-cell communication or quorum sensing (QS) is considered a stimulating approach for reducing bacterial pathogenicity and resistance[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

분자량

283.41

화학식

C16H29NO3

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

CCCCCCCCCCCC(N[C@H]1CCOC1=O)=O

선적

Room temperature in continental US; may vary elsewhere.

보관
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
용액&용해도
In Vitro: 

DMSO : 25 mg/mL (88.21 mM; ultrasonic and warming and heat to 80°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

H2O : < 0.1 mg/mL (insoluble)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.5285 mL 17.6423 mL 35.2846 mL
5 mM 0.7057 mL 3.5285 mL 7.0569 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • 몰농도 계산기

  • 농도 희석 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
순도&문서
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.5285 mL 17.6423 mL 35.2846 mL 88.2114 mL
5 mM 0.7057 mL 3.5285 mL 7.0569 mL 17.6423 mL
10 mM 0.3528 mL 1.7642 mL 3.5285 mL 8.8211 mL
15 mM 0.2352 mL 1.1762 mL 2.3523 mL 5.8808 mL
20 mM 0.1764 mL 0.8821 mL 1.7642 mL 4.4106 mL
25 mM 0.1411 mL 0.7057 mL 1.4114 mL 3.5285 mL
30 mM 0.1176 mL 0.5881 mL 1.1762 mL 2.9404 mL
40 mM 0.0882 mL 0.4411 mL 0.8821 mL 2.2053 mL
50 mM 0.0706 mL 0.3528 mL 0.7057 mL 1.7642 mL
60 mM 0.0588 mL 0.2940 mL 0.5881 mL 1.4702 mL
80 mM 0.0441 mL 0.2205 mL 0.4411 mL 1.1026 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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상품명:
N-dodecanoyl-L-Homoserine lactone
Cat. No.:
HY-118697
수량:
MCE Japan Authorized Agent: