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MCP-2

" in MedChemExpress (MCE) Product Catalog:

By Targets:	CCR (1) Small Interfering RNA (siRNA) (3)
By Research Areas:	Cancer (1) Endocrinology (1) Inflammation/Immunology (1) Neurological Disease (1)
Oligonucleotides:	Mouse Pre-designed siRNA Sets (1) Human Pre-designed siRNA Sets (2) siRNAs (3)

Inhibitors & Agonists

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Oligonucleotides

Bindarit 25+ Cited Publications AF2838	CCR	Neurological Disease Inflammation/Immunology Endocrinology Cancer
Bindarit (AF2838) is a selective inhibitor of the monocyte chemotactic proteins *MCP-1/CCL2, MCP-3/CCL7, and MCP-2/CCL8*, and no effect on other CC and CXC chemokines such as MIP-1α/CCL3, MIP-1β/CCL4, MIP-3/CCL23. Bindarit also has anti-inflammatory activity .

Ccl8 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Ccl8 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ccl8 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

CCL8 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
CCL8 Human Pre-designed siRNA Set A contains three designed siRNAs for CCL8 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

ADCK1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
ADCK1 Human Pre-designed siRNA Set A contains three designed siRNAs for ADCK1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

Bindarit 25+ Cited Publications AF2838	Neurological Disease Classification of Application Fields Ketones, Aldehydes, Acids Umbelliferae Plants Disease Research Fields Echinacea angustifolia DC. Endocrinology Source Classification Cancer	CCR
Bindarit (AF2838) is a selective inhibitor of the monocyte chemotactic proteins *MCP-1/CCL2, MCP-3/CCL7, and MCP-2/CCL8*, and no effect on other CC and CXC chemokines such as MIP-1α/CCL3, MIP-1β/CCL4, MIP-3/CCL23. Bindarit also has anti-inflammatory activity .

Species:	Human (4) Mouse (2)
Tag:	His (3) SUMO (1) Tag Free (2)
Source:	HEK293 (2) E. coli (4)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P75923

	MCP-2/CCL8 Protein, Human (SUMO) C-C motif chemokine 8; MCP-2; SCYA10; SCYA8	Human	E. coli
	MCP-2/CCL8 Protein, Human (SUMO) is a CC chemokine that interacts with CCR1, CCR2B, CCR3, and CCR5 to mediate host inflammatory immune responses, tumorigenesis, and antiviral infections. MCP-2/CCL8 Protein, Human (SUMO) is a recombinant human MCP-2/CCL8 (Q24-P99) protein expressed by E. coli with a N-SUMO tag.

HY-P7771

	MCP-2/CCL8 Protein, Mouse (HEK293, His) rMuCCL8, His; C-C motif chemokine 8; Ccl8; Monocyte chemoattractant protein 2; Monocyte chemotactic protein 2; MCP-2; Small-inducible cytokine A8; MCP2; Scya8	Mouse	HEK293
	MCP-2/CCL8 Protein, Mouse (HEK293, His) is a CC chemokine that interacts with CCR1, CCR2B, CCR3, and CCR5 to mediate host inflammatory immune responses, tumorigenesis, and antiviral infections. MCP-2/CCL8 Protein, Mouse (HEK293, His ) is a recombinant mouse MCP-2/CCL8 (E20-P97) protein expressed by HEK293 with a his tag.

HY-P7238

	MCP-2/CCL8 Protein, Human 1 Publications Verification rHuMCP-2/CCL8; C-C motif chemokine 8; MCP-2; SCYA10; SCYA8	Human	E. coli
	MCP-2/CCL8 Protein, Human is a CC chemokine that interacts with CCR1, CCR2B, CCR3, and CCR5 to mediate host inflammatory immune responses, tumorigenesis, and antiviral infections. MCP-2/CCL8 Protein, Human is a recombinant human MCP-2/CCL8 (Q24-P99) protein expressed by E. coli.

HY-P7239

	MCP-2/CCL8 Protein, Mouse 2 Publications Verification rMuMCP-2/CCL8; C-C motif chemokine 8; MCP-2; SCYA10; SCYA8	Mouse	E. coli
	MCP-2/CCL8 Protein, Mouse is a CC chemokine that interacts with CCR1, CCR2B, CCR3, and CCR5 to mediate host inflammatory immune responses, tumorigenesis, and antiviral infections. MCP-2/CCL8 Protein, Mouse is a recombinant mouse MCP-2/CCL8 (G24-P97) protein expressed by E. coli.

HY-P704779

	MCP-2/CCL8 Protein, Human (His) rHuMCP-2/CCL8; C-C motif chemokine 8; MCP-2; SCYA10; SCYA8	Human	E. coli
	MCP-2/CCL8 Protein, Human (His) is the recombinant human-derived MCP-2/CCL8 protein, expressed by E. coli, with N-His tag.

HY-P7770

	MCP-2/CCL8 Protein, Human (HEK293, His) 1 Publications Verification rHuCCL8, His; C-C Motif Chemokine 8; HC14; Monocyte Chemoattractant Protein 2; Monocyte Chemotactic Protein 2; MCP-2; Small-Inducible Cytokine A8; CCL8; MCP2; SCYA10; SCYA8	Human	HEK293
	MCP-2/CCL8 Protein, Human (HEK293, His) is a CC chemokine that interacts with CCR1, CCR2B, CCR3, and CCR5 to mediate host inflammatory immune responses, tumorigenesis, and antiviral infections. MCP-2/CCL8 Protein, Human (HEK293, His ) is a recombinant human MCP-2/CCL8 (Q24-P99) protein expressed by HEK293 with a his tag.

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Ccl8 Mouse Pre-designed siRNA Set A		siRNAs Mouse Pre-designed siRNA Sets
Ccl8 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ccl8 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

CCL8 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
CCL8 Human Pre-designed siRNA Set A contains three designed siRNAs for CCL8 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

ADCK1 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
ADCK1 Human Pre-designed siRNA Set A contains three designed siRNAs for ADCK1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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