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Pathways Recommended: Stem Cell/Wnt Cell Cycle/DNA Damage
Results for "

Madin Darby canine kidney (MDCK) cell

" in MedChemExpress (MCE) Product Catalog:

4

Inhibitors & Agonists

1

Natural
Products

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-130178
    CL-385319

    		Endogenous Metabolite Infection
    CL-385319 is an N-substituted piperidine compound with inhibitory activity against H5N1 avian influenza A virus infection. CL-385319 exhibited an IC50 of 27.03±2.54 μM against infection of highly pathogenic H5N1 virus in Madin-Darby canine kidney cells (MDCK). CL-385319 had low cytotoxicity with a CC50 of 1.48 mM and was able to inhibit the entry of pseudoviruses carrying H5N1 strains from different sources, but had no inhibitory effect on the entry of VSV-G pseudotyped particles. Pseudoviruses with the M24A mutation in HA1 or the F110S mutation in HA2 were resistant to CL-385319, indicating that these two residues in the cavity region may be critical for the binding of CL-385319 .
    CL-385319
  • HY-158881
    DDG

    		Biochemical Assay Reagents Inflammation/Immunology
    DDG is a type of detergent that can dissolve membrane proteins (MPs) in bacterial membranes, insect cells, and Madin Darby Canine Kidney (MDCK) cells .
    DDG
  • HY-120885
    (+)-Oxanthromicin

    		Ras Cancer
    (+)-Oxanthromicin (Compound 1) mislocalizes the oncogenic mutant K-Ras from the plasma membrane of intact Madin-Darby canine kidney (MDCK) cells, and exhibits thereby antitumor efficacy .
    (+)-Oxanthromicin
  • HY-W714201
    Nitralin

    		Herbicide Parasite Infection
    Nitralin is a dinitroaniline herbicide. Nitralin exhibits inhibitory activity against Cryptosporidium parvum, with a IC50 of 4.5 µM .
    Nitralin

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