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Isoforms Recommended:	PAK2

Results for "

PAK2

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Apoptosis (2) PAK (9) Salt-inducible Kinase (SIK) (1) Small Interfering RNA (siRNA) (3)
By Research Areas:	Cancer (9)

12

Inhibitors & Agonists

2

Recombinant Proteins

1

Antibodies

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

*NVS-PAK1-C*	PAK	Cancer
NVS-PAK1-C is a potent, ATP-competitive and specific allosteric *PAK1* inhibitor probe with IC₅₀ values of 5 nM and 6 nM for dephosphorylated PAK1 and phosphorylated PAK1, respectively. NVS-PAK1-C is also against dephosphorylated PAK2 (IC₅₀=270 nM) and phosphorylated PAK2 (IC₅₀=720 nM) .

HY-19538

FRAX1036

2 Publications Verification

PAK Cancer

FRAX1036 is a PAK inhibitor with K_is of 23.3 nM, 72.4 nM, and 2.4 μM for PAK1, PAK2 and PAK4, respectively.

PAK2 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
PAK2 Human Pre-designed siRNA Set A contains three designed siRNAs for PAK2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PAK2 Human Pre-designed siRNA Set A PAK2 Human Pre-designed siRNA Set A

Pak2 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Pak2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Pak2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Pak2 Mouse Pre-designed siRNA Set A Pak2 Mouse Pre-designed siRNA Set A

PAK2 Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
PAK2 Rat Pre-designed siRNA Set A contains three designed siRNAs for PAK2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

PAK2 Rat Pre-designed siRNA Set A PAK2 Rat Pre-designed siRNA Set A

HY-116917

G-9791

PAK Cancer

G-9791, a poyridone side chain analogue, is a potent PAK inhibitor with K_i values of 0.95 nM and 2.0 nM for PAK1 and PAK2, respectively .

FRAX486 Maximum Cited Publications 6 Publications Verification	PAK	Cancer
FRAX486 is a p21-activated kinase (PAK) inhibitor with IC₅₀s of 14, 33 and 39 nM for PAK1, PAK2 and PAK3, respectively.

HY-19635

G-5555

5 Publications Verification

PAK Cancer

G-5555 is a potent p21-activated kinase 1 (PAK1) inhibitor with K_is of 3.7 nM and 11 nM for PAK1 and PAK2, respectively.

MRIA9	Salt-inducible Kinase (SIK) PAK Apoptosis	Cancer
MRIA9 is an ATP-competitive, pan Salt-Inducible kinase (SIK) and *PAK2/3* inhibitor, with IC₅₀ values of 516 nM, 180 nM and 127 nM for SIK1, SIK2 and SIK3, respectively .

AZ13705339	PAK	Cancer
AZ13705339 is a highly potent and selective *PAK1* inhibitor with IC₅₀s of 0.33 nM and 59 nM for PAK1 and pPAK1, respectively. AZ13705339 has binding affinities to PAK1 and PAK2, with K_ds of 0.28 nM and 0.32 nM, respectively. AZ13705339 can be used in the research of cancers .

AZ13705339 hemihydrate	PAK	Cancer
AZ13705339 hemihydrate is a highly potent and selective *PAK1* inhibitor with IC₅₀s of 0.33 nM and 59 nM for PAK1 and pPAK1, respectively. AZ13705339 hemihydrate has binding affinities to PAK1 and PAK2, with K_ds of 0.28 nM and 0.32 nM, respectively. AZ13705339 hemihydrate can be used in the research of cancers .

ZMF-10	PAK Apoptosis	Cancer
ZMF-10 is a highly potent *PAK1* inhibitor, with IC₅₀s of 174 nM, 1.038 μM and 1.372 μM for PAK1, PAK2 and PAK3, respectively. ZMF-10 can inhibit PAK1 activity to affect PAK1-regulated apoptosis, ER-Stress and migration in MDA-MB-231 cells. ZMF-10 can be used for researching anticancer .

Species:	Human (2)
Tag:	His (1) GST (2)
Source:	Sf9 insect cells (2)

Cat. No.	Compare	Product Name	Species	Source

	PKN2 Protein, Human (sf9, His, GST) PKN2; protein kinase N2; PRKCL2, protein kinase C like 2; serine/threonine-protein kinase N2; cardiolipin activated protein kinase PAK2; PAK 2; PRK2; PKN gamma; protein kinase C-like 2; protein-kinase C-related kinase 2; cardiolipin-activated protein kinase PAK2; PAK2; PAK-2; PRKCL2; PRO2042; MGC71074; MGC150606	Human	Sf9 insect cells

HY-P702745

PAK2 Protein, Human (sf9, GST)

PAK2; p21 (RAC1) activated kinase 2; KNO2; PAK65; PAKgamma
Human Sf9 insect cells

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