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PLAUR Human Pre-designed siRNA Set A contains three designed siRNAs for PLAUR gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
The uPAR protein acts as a receptor for urokinase plasminogen activator, facilitating plasmin formation and signal transduction activation. It interacts with SRPX2 and forms a monomer. uPAR also interacts with MRC2 and SORL1, reducing PLAUR internalization. Additionally, the PLAUR-PLAU-SERPINE1 complex interacts with SORL1. uPAR Protein, Mouse (Biotinylated, HEK293, His-Avi) is the recombinant mouse-derived uPAR protein, expressed by HEK293 , with C-Avi, C-His labeled tag. The total length of uPAR Protein, Mouse (Biotinylated, HEK293, His-Avi) is 275 a.a., with molecular weight of 55-65 kDa.
uPAR Protein, a receptor for urokinase plasminogen activator, actively localizes and facilitates plasmin formation. It mediates proteolysis-independent signal transduction activated by U-PA and undergoes negative-feedback regulation. As a monomer, it interacts with MRC2, SRPX2, and FAP at invadopodia. Engaging SORL1, it forms a ternary complex with PLAUR, PLAU, and SERPINE1, influencing PLAUR internalization. The interaction with SORL1 occurs via the N-terminal ectodomain, highlighting uPAR's multifaceted role in cellular functions. uPAR Protein, Human (Domain 2&3, HEK293, His) is the recombinant human-derived uPAR protein, expressed by HEK293, with C-His labeled tag. The total length of uPAR Protein, Human (Domain 2&3, HEK293, His) is 191 a.a., with molecular weight of 33-45 kDa.
uPAR Protein, a receptor for urokinase plasminogen activator, actively localizes and facilitates plasmin formation. It mediates proteolysis-independent signal transduction activated by U-PA and undergoes negative-feedback regulation. As a monomer, it interacts with MRC2, SRPX2, and FAP at invadopodia. Engaging SORL1, it forms a ternary complex with PLAUR, PLAU, and SERPINE1, influencing PLAUR internalization. The interaction with SORL1 occurs via the N-terminal ectodomain, highlighting uPAR's multifaceted role in cellular functions. uPAR Protein, Human (Domain 3, HEK293, His) is the recombinant human-derived uPAR protein, expressed by HEK293, with C-His labeled tag. The total length of uPAR Protein, Human (Domain 3, HEK293, His) is 92 a.a., with molecular weight of 25-35 kDa.
uPAR Protein, a receptor for urokinase plasminogen activator, actively localizes and facilitates plasmin formation. It mediates proteolysis-independent signal transduction activated by U-PA and undergoes negative-feedback regulation. As a monomer, it interacts with MRC2, SRPX2, and FAP at invadopodia. Engaging SORL1, it forms a ternary complex with PLAUR, PLAU, and SERPINE1, influencing PLAUR internalization. The interaction with SORL1 occurs via the N-terminal ectodomain, highlighting uPAR's multifaceted role in cellular functions. uPAR Protein, Human (Domain 1, HEK293, His) is the recombinant human-derived uPAR protein, expressed by HEK293, with C-His labeled tag. The total length of uPAR Protein, Human (Domain 1, HEK293, His) is 92 a.a., with molecular weight of 17-25 kDa.
uPAR Protein, a receptor for urokinase plasminogen activator, actively localizes and facilitates plasmin formation. It mediates proteolysis-independent signal transduction activated by U-PA and undergoes negative-feedback regulation. As a monomer, it interacts with MRC2, SRPX2, and FAP at invadopodia. Engaging SORL1, it forms a ternary complex with PLAUR, PLAU, and SERPINE1, influencing PLAUR internalization. The interaction with SORL1 occurs via the N-terminal ectodomain, highlighting uPAR's multifaceted role in cellular functions. uPAR Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived uPAR protein, expressed by HEK293, with C-Avi, C-His labeled tag. The total length of uPAR Protein, Human (Biotinylated, HEK293, His-Avi) is 283 a.a., with molecular weight of 50-65 kDa.
The uPAR protein is a receptor for urokinase plasminogen activator and actively localizes and promotes plasmin formation. It mediates proteolysis-independent signaling activated by U-PA and undergoes negative feedback regulation. uPAR Protein, Human (GST) is the recombinant human-derived uPAR protein, expressed by E. coli , with N-GST labeled tag.
The uPAR protein acts as a receptor for urokinase plasminogen activator, facilitating plasmin formation and signal transduction activation. It interacts with SRPX2 and forms a monomer. uPAR also interacts with MRC2 and SORL1, reducing PLAUR internalization. Additionally, the PLAUR-PLAU-SERPINE1 complex interacts with SORL1. uPAR Protein, Mouse (HEK293, His-Avi) is the recombinant mouse-derived uPAR protein, expressed by HEK293 , with C-Avi, C-His labeled tag. The total length of uPAR Protein, Mouse (HEK293, His-Avi) is 275 a.a., with molecular weight of 50-65 kDa.
uPAR Protein, a receptor for urokinase plasminogen activator, actively localizes and facilitates plasmin formation. It mediates proteolysis-independent signal transduction activated by U-PA and undergoes negative-feedback regulation. As a monomer, it interacts with MRC2, SRPX2, and FAP at invadopodia. Engaging SORL1, it forms a ternary complex with PLAUR, PLAU, and SERPINE1, influencing PLAUR internalization. The interaction with SORL1 occurs via the N-terminal ectodomain, highlighting uPAR's multifaceted role in cellular functions. uPAR Protein, Human (HEK293, His-Avi) is the recombinant human-derived uPAR protein, expressed by HEK293, with C-Avi, C-His labeled tag. The total length of uPAR Protein, Human (HEK293, His-Avi) is 283 a.a., with molecular weight of 50-60 kDa.
uPAR Protein, a receptor for urokinase plasminogen activator, crucially localizes and facilitates plasmin formation. It mediates proteolysis-independent signal transduction by U-PA, regulated through negative feedback. uPAR, typically a monomer, interacts with SRPX2, MRC2, and forms a complex with FAP at invadopodia, contributing to proteolysis and signaling. It engages in a ternary complex with PLAU and SERPINE1, also interacting with SORL1, highlighting multifaceted cellular functions. uPAR Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived uPAR protein, expressed by HEK293, with C-His labeled tag. The total length of uPAR Protein, Cynomolgus (HEK293, His) is 283 a.a., with molecular weight of 60-70 kDa.
The uPAR protein is a receptor for urokinase plasminogen activator and actively localizes and promotes plasmin formation. It mediates proteolysis-independent signaling activated by U-PA and undergoes negative feedback regulation. FITC-Labeled uPAR Protein, Human (HEK293, His) is the recombinant human-derived FITC-Labeled uPAR protein, expressed by HEK293 , with His labeled tag. The total length of FITC-Labeled uPAR Protein, Human (HEK293, His) is 281 a.a., with molecular weight of 45-60 kDa.
uPAR (urokinase plasminogen activator receptor) possesses enzyme, protein, and receptor binding activities. It regulates apoptotic signaling, epidermal growth factor signaling, and cytochrome c release. uPAR is widely expressed in structures like decidua and spleen. Its human ortholog, PLAUR, is linked to rheumatoid arthritis. Investigating uPAR can reveal its role in cellular processes and shed light on diseases like rheumatoid arthritis. uPAR Protein, Mouse (HEK293, His-Fc) is the recombinant mouse-derived uPAR protein, expressed by HEK293 , with C-hFc, C-His labeled tag. The total length of uPAR Protein, Mouse (HEK293, His-Fc) is 274 a.a., with molecular weight of 80-90 kDa.
The uPAR protein acts as a receptor for urokinase plasminogen activator, facilitating plasmin formation and signal transduction activation. It interacts with SRPX2 and forms a monomer. uPAR also interacts with MRC2 and SORL1, reducing PLAUR internalization. Additionally, the PLAUR-PLAU-SERPINE1 complex interacts with SORL1. uPAR Protein, Mouse (HEK293, His) is the recombinant mouse-derived uPAR protein, expressed by HEK293, with C-His labeled tag. The total length of uPAR Protein, Mouse (HEK293, His) is 297 a.a., with molecular weight of 50-60 kDa.
The uPAR protein is a receptor for urokinase plasminogen activator and actively localizes and promotes plasmin formation. It mediates proteolysis-independent signaling activated by U-PA and undergoes negative feedback regulation. uPAR Protein, Human (HEK293, His) is the recombinant human-derived uPAR protein, expressed by HEK293 , with C-6*His labeled tag. The total length of uPAR Protein, Human (HEK293, His) is 281 a.a., with molecular weight of ~52 kDa.
LYPD3/C4.4A protein facilitates cell migration and potentially influences urothelial cell-matrix interactions. It plays a role in tumor progression, binding to laminin-1 and laminin-5. Interactions with LGALS3, AGR2, and AGR3 emphasize its functional associations and impact in diverse biological processes. LYPD3/C4.4A Protein, Human (HEK293, His) is the recombinant human-derived LYPD3/C4.4A protein, expressed by HEK293 , with C-6*His labeled tag. The total length of LYPD3/C4.4A Protein, Human (HEK293, His) is 256 a.a., with molecular weight of 55-75 kDa.
The LYPD3/C4.4A protein is a multifunctional cell surface molecule that is critical for cell migration and has been implicated in potential tumor progression. It binds laminin 1 and laminin 5, emphasizing its role in extracellular matrix interactions. LYPD3/C4.4A Protein, Mouse (HEK293, His) is the recombinant mouse-derived LYPD3/C4.4A protein, expressed by HEK293 , with C-His labeled tag. The total length of LYPD3/C4.4A Protein, Mouse (HEK293, His) is 255 a.a., with molecular weight of ~45-75 kDa.
SLURP2 protein affects keratinocyte proliferation, differentiation, and apoptosis by binding to and potentially modulating nicotinic and muscarinic acetylcholine receptors. In vitro studies have shown that SLURP2 has a moderate inhibitory effect on nAChRs containing α-3:β-2, a strong inhibitory effect on nAChRs containing α-4:β-2, regulates nAChRs containing α-7, and inhibits Nicotine-induced signaling may involve nAChRs containing α-3:β-4. SLURP2 Protein, Human (P.pastoris, His) is the recombinant human-derived SLURP2 protein, expressed by P. pastoris , with N-His labeled tag. The total length of SLURP2 Protein, Human (P.pastoris, His) is 75 a.a., with molecular weight of ~10.0 kDa.
