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Results for "

PSGL-1

" in MedChemExpress (MCE) Product Catalog:

4

Inhibitors & Agonists

4

Inhibitory Antibodies

9

Recombinant Proteins

1

Antibodies

Cat. No. Compare Product Name Species Source
  • HY-P72485

    P-selectin glycoprotein ligand 1; PSGL-1; Selectin P ligand; CD162; SELPLG

    Human HEK293
    CD162/PSGL-1 Protein, a cell surface receptor, plays a crucial role in leukocyte trafficking and adhesion. Dysregulation of CD162/PSGL-1 Protein has been associated with inflammatory diseases and impaired immune responses. Targeting CD162/PSGL-1 Protein may offer potential therapeutic interventions in these conditions by modulating leukocyte trafficking, enhancing immune responses, and managing inflammatory disorders. CD162/PSGL-1 Protein, Human (254a.a, HEK293, Fc) is the recombinant human-derived CD162/PSGL-1 protein, expressed by HEK293, with C-hFc labeled tag. The total length of CD162/PSGL-1 Protein, Human (254a.a, HEK293, Fc) is 254 a.a., with molecular weight of 100-130 kDa.
  • HY-P700816

    CLA; PSGL-1; PSGL1; CD162; SELPLG; Selectin P ligand; Selp1; Selpl

    Mouse HEK293
    CD162/PSGL-1 protein, an SLe(x)-type proteoglycan, facilitates early inflammation stages by mediating rapid leukocyte rolling through high-affinity interactions with E- and P-selectins. CD162 forms homodimers linked by disulfide bonds, interacting with selectins through lectin/EGF domains. For high-affinity P-selectin binding, sialyl Lewis X glycan modification and tyrosine sulfation, likely on Tyr-54, are required. Dimerization seems dispensable. CD162 also interacts with SNX20, mediating SYK activation, and with MSN and SYK, contributing to downstream signaling events. Its engagement with HAVCR1 reveals diverse cellular interactions. CD162/PSGL-1 Protein, Mouse (266a.a, HEK293, His) is the recombinant mouse-derived CD162/PSGL-1 protein, expressed by HEK293, with C-His labeled tag. The total length of CD162/PSGL-1 Protein, Mouse (266a.a, HEK293, His) is 266 a.a., with molecular weight of 68-108 kDa.
  • HY-P77166

    P-selectin glycoprotein ligand 1; PSGL-1; Selectin P ligand; CD162; SELPLG

    Mouse HEK293
    CD162/PSGL-1 protein, an SLe(x)-type proteoglycan, facilitates early inflammation stages by mediating rapid leukocyte rolling through high-affinity interactions with E- and P-selectins. CD162 forms homodimers linked by disulfide bonds, interacting with selectins through lectin/EGF domains. For high-affinity P-selectin binding, sialyl Lewis X glycan modification and tyrosine sulfation, likely on Tyr-54, are required. Dimerization seems dispensable. CD162 also interacts with SNX20, mediating SYK activation, and with MSN and SYK, contributing to downstream signaling events. Its engagement with HAVCR1 reveals diverse cellular interactions. CD162/PSGL-1 Protein, Mouse (307a.a, HEK293, Fc) is the recombinant mouse-derived CD162/PSGL-1 protein, expressed by HEK293, with C-hFc labeled tag. The total length of CD162/PSGL-1 Protein, Mouse (307a.a, HEK293, Fc) is 307 a.a., with molecular weight of ~82 kDa.
  • HY-P700815

    CLA; PSGL-1; PSGL1; CD162; SELPLG; Selectin P ligand; Selp1; Selpl

    Cynomolgus HEK293
    As a member of the selectin family, CD162/PSGL-1 is mainly expressed in some immune or inflammatory cells. CD162/PSGL-1 deficiency affects myeloid differentiation and lymphocyte maturation and therefore has important implications for cell differentiation. CD162/PSGL-1 can be used as an immune checkpoint modulator and may be a new target for cancer therapy. CD162/PSGL-1 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived CD162/PSGL-1 protein, expressed by HEK293 , with C-His labeled tag. The total length of CD162/PSGL-1 Protein, Cynomolgus (HEK293, His) is 323 a.a., with molecular weight of 72-82 kDa.
  • HY-P77162

    P-selectin glycoprotein ligand 1; PSGL-1; Selectin P ligand; CD162; SELPLG

    Human HEK293
  • HY-P77164

    P-selectin glycoprotein ligand 1; PSGL-1; Selectin P ligand; CD162; SELPLG

    Human HEK293
  • HY-P77163

    P-selectin glycoprotein ligand 1; PSGL-1; Selectin P ligand; CD162; SELPLG

    Human HEK293
    CD162/PSGL-1 Protein, a cell surface receptor, plays a crucial role in leukocyte trafficking and adhesion. Dysregulation of CD162/PSGL-1 Protein has been associated with inflammatory diseases and impaired immune responses. Targeting CD162/PSGL-1 Protein may offer potential therapeutic interventions in these conditions by modulating leukocyte trafficking, enhancing immune responses, and managing inflammatory disorders. CD162/PSGL-1 Protein, Human (HEK293, His) is the recombinant human-derived CD162/PSGL-1 protein, expressed by HEK293, with C-His labeled tag. The total length of CD162/PSGL-1 Protein, Human (HEK293, His) is 295 a.a., with molecular weight of ~89 & 61 kDa, respectively.
  • HY-P77165

    P-selectin glycoprotein ligand 1; PSGL-1; Selectin P ligand; CD162; SELPLG

    Mouse HEK293
    CD162/PSGL-1 protein, an SLe(x)-type proteoglycan, facilitates early inflammation stages by mediating rapid leukocyte rolling through high-affinity interactions with E- and P-selectins. CD162 forms homodimers linked by disulfide bonds, interacting with selectins through lectin/EGF domains. For high-affinity P-selectin binding, sialyl Lewis X glycan modification and tyrosine sulfation, likely on Tyr-54, are required. Dimerization seems dispensable. CD162 also interacts with SNX20, mediating SYK activation, and with MSN and SYK, contributing to downstream signaling events. Its engagement with HAVCR1 reveals diverse cellular interactions. CD162/PSGL-1 Protein, Mouse (HEK293) is the recombinant mouse-derived CD162/PSGL-1 protein, expressed by HEK293, with tag free. The total length of CD162/PSGL-1 Protein, Mouse (HEK293) is 307 a.a., with molecular weight of ~54.9 kDa.
  • HY-P7800

    rMuCD162, C-Fc; PSGL-1; CD162; SELPLG; CLA;

    Mouse HEK293
    CD162/PSGL-1 Protein, Mouse (266a.a, HEK293, Fc) is a recombinant mouse CD162 expressed in HEK 293 cells with a C-Fc tag at the C-terminus. CD162/PSGL-1 Protein plays an important role in immunity and homeostasis .

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