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Results for "

Phenylalanyl

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Amino Acid Derivatives (5) Aminoacyl-tRNA Synthetase (1) Bacterial (2) Biochemical Assay Reagents (3) CD38 (1) Drug Intermediate (4) Drug-Linker Conjugates for ADC (1) Endothelin Receptor (1) IKZF Family (1) Influenza Virus (1) Ligands for E3 Ligase (1) MMP (1) Molecular Glues (1) TGF-β Receptor (1) Topoisomerase (1)
By Research Areas:	Cancer (4) Cardiovascular Disease (2) Infection (5)

Inhibitors & Agonists

Peptides

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Products

Cat. No.	상품명	Target	연구분야	Chemical Structure

HY-129047C

TPCK-treated Trypsin 1 Publications Verification	Biochemical Assay Reagents Influenza Virus	Infection
TPCK-treated Trypsin is a trypsin whose activity is inhibited by tosyl phenylalanyl chloromethyl ketone. TPCK-treated Trypsin reduces autolysis and nonspecific proteolysis during experiments, exhibits stability in storage and handling. TPCK-treated trypsin can be used in proteomics research . TPCK-treated Trypsin renders the virus hemagglutinin active, which allows multicycle replication of the virus. TPCK-treated Trypsin can be used for the study of influenza virus .

HY-153360

MC-GGFG-AM-(10Me-11F-Camptothecin)	Drug-Linker Conjugates for ADC Topoisomerase	Cancer
MC-GGFG-AM-(10Me-11F-Camptothecin) is a linker-payload conjugate used to synthesize ZW251. ZW251 an antibody-drug conjugate (ADC) targeting human GPC3. ZW251 consists of a humanized IgG1 antibody conjugated to a novel camptothecin-based topoisomerase 1 inhibitor, ZD06519, via a linker. The linker is the maleimide anchor and a glycyl glycyl phenylalanyl glycine (GGFG)-aminomethyl (AM) cleavable linker. ZW251 has high affinity with human and cynomolgus monkey GPC3. ZW251 displays rapid internalization in GPC3-expressing HCC cell lines, and bystander-mediated killing of GPC3 negative cancer cells .

HY-W068839

H-Phe-Leu-OH L-Phenylalanyl-L-leucine; Phe-Leu	Amino Acid Derivatives	Others
H-Phe-Leu-OH is a leucine derivative .

HY-122542A

PPACK dihydrochloride 2 Publications Verification Pebac; D-Phenylalanyl-prolyl-arginyl Chloromethyl Ketone; D-Phe-Pro-Arg-CH2Cl	Ligands for E3 Ligase Molecular Glues IKZF Family	Cardiovascular Disease
PPACK dihydrochloride is an orally active, selective molecular glue degrader targeting IKZF2. Through a molecular glue mechanism, PPACK dihydrochloride binds to CRBN, recruits IKZF2 to form a ternary complex, and promotes its ubiquitination and proteasomal degradation. This further converts inhibitory regulatory T cells (T_reg) into effector-like T cells, enhances CD8 ⁺ T cell responses, and modulates the T_eff:T_reg balance. PPACK dihydrochloride also increases the production of the inflammatory cytokine IL-2 and reduces the suppressive activity of T_reg. PPACK dihydrochloride can be used in cancer immunotherapy research, and exhibits a synergistic effect when combined with immune checkpoint inhibitors such as anti-PD1 .

HY-W008733

*L-Phenylalanyl-L-valine* L-Phe-L-Val; Phe-Val; H-Phe-Val-OH	Amino Acid Derivatives	Others
L-Phenylalanyl-L-valine (L-Phe-L-Val) is a valine derivative .

HY-W048829

Boc-Phe-Gly-OH	Amino Acid Derivatives	Others
Boc-Phe-Gly-OH is a Boc-protected phenylalanyl glycine derivative, can be used for the synthesis of agents or other compounds .

HY-128994A

GGFG-Exatecan TFA	Drug Intermediate	Cancer
GGFG-Exatecan TFA is a synthetic intermediate for drug-linker conjugates used in antibody-drug conjugates (ADCs). GGFG-Exatecan TFA consists of a glycyl-glycyl-phenylalanyl-glycine (GGFG) tetrapeptide linker and a DNA topoisomerase I inhibitor Exatecan (HY-13631). GGFG-Exatecan TFA can be used for the study of cancer .

HY-W967223

*L-Phenylalanyl-L-threonine* Phe-Thr; H-Phe-Thr-OH	Amino Acid Derivatives	Others
L-Phenylalanyl-L-threonine is a dipeptide containing Phenylalanine and threonine. L-Phenylalanyl-L-threonine can be used to synthesize the cyclic hexapeptide Banyascyclamide A .

HY-P10563

Noraramtide BHV-1100	CD38	Cancer
Noraramtide (BHV-1100) is an antibody recruitment molecule. Noraramtide can specifically bind to CD38 molecules to recruit natural killer (NK) cells. Noraramtide enhances the ability of NK cells to kill tumor cells through antibody-dependent cellular cytotoxicity (ADCC). This mechanism allows NK cells to more effectively recognize and eliminate tumor cells while avoiding mutual killing between NK cells. Noraramtide can be used for the study of autologous cancer immunity .

HY-128994

GGFG-Exatecan	Drug Intermediate	Cancer
GGFG-Exatecan is a synthetic intermediate for drug-linker conjugates used in antibody-drug conjugates (ADCs). GGFG-Exatecan consists of a glycyl-glycyl-phenylalanyl-glycine (GGFG) tetrapeptide linker and a DNA topoisomerase I inhibitor Exatecan (HY-13631). GGFG-Exatecan can be used for the study of cancer .

HY-P3350

LS-BF1	Bacterial	Infection
LS-BF1 is a stable and low toxic cationic antimicrobial peptide. LS-BF1 displays broad spectrum of antibacterial activity, including the challenging ESKAPE pathogens, by cell membrane disruptive mechanism. LS-BF1 shows good in vivo efficacy for elimination of bacteria in a mouse infection model[1].

HY-105168

TAK 044	Endothelin Receptor	Cardiovascular Disease
TAK 044 is an antagonist of Endothelin Receptor. TAK 044 strongly inhibits ET-induced deterioration in various animal models. TAK 044 can be used in study ET-related diseases such as acute myocardial infarction,acute renal failure, acute hepatic malfunction, and subarachnoid hemorrhage .

HY-W275220

PEA-NBOMe hydrochloride	Aminoacyl-tRNA Synthetase	Infection
PEA-NBOMe hydrochloride (Compound 21) is a competitive phenylalanyl-tRNA synthetase (PRS) inhibitor (K_i=0.92 μM), which is found in Escherichia coli. PEA-NBOMe hydrochloride is promising for research of antibacterial or antiviral agents .

HY-N8497

Leoidin	Bacterial	Infection
Leoidin is an OATP1B1 and OATP1B3 inhibitor with K_i values of 0.08 and 1.84 μM，respectively. Leoidin inhibits sodium fluorescein uptake in CHO cells expressing the human OATP1B1 and OATP1B3. Leoidin is an antibacterial agent against both Gram-positive and Gram-negative pathogens. Leoidin inhibits phenylalanyl-tRNA synthetase (PheRS) (IC₅₀= 42 μM) and inhibits protein synthesis in bacterial. Leoidin can be isolated from L. gangaleoides .

HY-165339

*Lysyl-phenylalanyl-lysine*	TGF-β Receptor MMP	Others
Lysyl-phenylalanyl-lysine (Compound KFK) is a tripeptide and belongs to the peptide segments related to thrombospondin-1 (TSP-1) (HY-P0299). Lysyl-phenylalanyl-lysine can activate LAP-TGF-β1 and release active TGF-β1, thereby inhibiting abnormal expression of MMP. Lysyl-phenylalanyl-lysine can be used for research on skin aging-related diseases and poor wound healing .

HY-W250140

*Boc-D-phenylalanyl-D-phenylalanine*	Biochemical Assay Reagents	Others
Boc-D-phenylalanyl-D-phenylalanine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-114844

*L-Phenylalanyl-L-glutamic acid* H-Phe-Glu-OH	Amino Acid Derivatives Drug Intermediate	Infection
L-Phenylalanyl-L-glutamic acid (H-Phe-Glu-OH) is a dipeptide present in the exudates of alfalfa seedlings, which exhibits high affinity for PEPT2. L-Phenylalanyl-L-glutamic acid can serve as the peptide scaffold of a tyrosyl-tRNA synthetase inhibitor against Staphylococcus aureus .

HY-136665

Boc-D-Phe-Pro-OH tert-Butoxycarbonyl-D-Phenylalanyl-L-proline	Drug Intermediate	Others
Boc-D-Phe-Pro-OH (tert-Butoxycarbonyl-D-phenylalanyl-L-proline) is a synthetic intermediate useful for pharmaceutical synthesis.

HY-P4948

Coumarin-Phalloidin	Biochemical Assay Reagents	Others
Coumarin-phalloidin is a kind of phalloidin labeled with Coumarin (HY-N0709). Coumarin-phalloidin is a new type of actin probe that can be used for triple immunofluorescence microscopic observation of the cell skeleton .

Cat. No.	상품명	Target	Research Area

HY-W068839

H-Phe-Leu-OH L-Phenylalanyl-L-leucine; Phe-Leu	Amino Acid Derivatives	Others
H-Phe-Leu-OH is a leucine derivative .

HY-W008733

*L-Phenylalanyl-L-valine* L-Phe-L-Val; Phe-Val; H-Phe-Val-OH	Amino Acid Derivatives	Others
L-Phenylalanyl-L-valine (L-Phe-L-Val) is a valine derivative .

HY-W048829

Boc-Phe-Gly-OH	Amino Acid Derivatives	Others
Boc-Phe-Gly-OH is a Boc-protected phenylalanyl glycine derivative, can be used for the synthesis of agents or other compounds .

HY-W967223

*L-Phenylalanyl-L-threonine* Phe-Thr; H-Phe-Thr-OH	Amino Acid Derivatives	Others
L-Phenylalanyl-L-threonine is a dipeptide containing Phenylalanine and threonine. L-Phenylalanyl-L-threonine can be used to synthesize the cyclic hexapeptide Banyascyclamide A .

HY-P10563

Noraramtide BHV-1100	CD38	Cancer
Noraramtide (BHV-1100) is an antibody recruitment molecule. Noraramtide can specifically bind to CD38 molecules to recruit natural killer (NK) cells. Noraramtide enhances the ability of NK cells to kill tumor cells through antibody-dependent cellular cytotoxicity (ADCC). This mechanism allows NK cells to more effectively recognize and eliminate tumor cells while avoiding mutual killing between NK cells. Noraramtide can be used for the study of autologous cancer immunity .

HY-P3350

LS-BF1	Bacterial	Infection
LS-BF1 is a stable and low toxic cationic antimicrobial peptide. LS-BF1 displays broad spectrum of antibacterial activity, including the challenging ESKAPE pathogens, by cell membrane disruptive mechanism. LS-BF1 shows good in vivo efficacy for elimination of bacteria in a mouse infection model[1].

HY-105168

TAK 044	Endothelin Receptor	Cardiovascular Disease
TAK 044 is an antagonist of Endothelin Receptor. TAK 044 strongly inhibits ET-induced deterioration in various animal models. TAK 044 can be used in study ET-related diseases such as acute myocardial infarction,acute renal failure, acute hepatic malfunction, and subarachnoid hemorrhage .

HY-78824

*Glycine, N-[(1,1-dimethylethoxy)carbonyl]thio-L-phenylalanyl-, methyl ester*	Peptides	Others
Glycine, N-[(1,1-dimethylethoxy)carbonyl]thio-L-phenylalanyl-, methyl ester (compound 3b) is a polypeptide compound containing sulfamide, can be used to synthesis peptide-agent coupling compounds .

HY-P4948

Coumarin-Phalloidin	Biochemical Assay Reagents	Others
Coumarin-phalloidin is a kind of phalloidin labeled with Coumarin (HY-N0709). Coumarin-phalloidin is a new type of actin probe that can be used for triple immunofluorescence microscopic observation of the cell skeleton .

Cat. No.	상품명	Category	Target	Chemical Structure

HY-N8497

Leoidin	Monophenols Microorganisms Phenols Source Classification	Bacterial
Leoidin is an OATP1B1 and OATP1B3 inhibitor with K_i values of 0.08 and 1.84 μM，respectively. Leoidin inhibits sodium fluorescein uptake in CHO cells expressing the human OATP1B1 and OATP1B3. Leoidin is an antibacterial agent against both Gram-positive and Gram-negative pathogens. Leoidin inhibits phenylalanyl-tRNA synthetase (PheRS) (IC₅₀= 42 μM) and inhibits protein synthesis in bacterial. Leoidin can be isolated from L. gangaleoides .

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Phenylalanyl

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