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Results for "

ROCK-IN-1

" in MedChemExpress (MCE) Product Catalog:

9

Inhibitors & Agonists

1

Fluorescent Dye

1

Biochemical Assay Reagents

1

Natural
Products

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-U00351
    ROCK-IN-1
    1 Publications Verification

    		 ROCK Cardiovascular Disease Inflammation/Immunology
    ROCK-IN-1 is a potent inhibitor of ROCK, with an IC50 of 1.2 nM for ROCK2.
    <em>ROCK-IN-1</em>
  • HY-10319
    BAY-549
    2 Publications Verification

    ROCK-IN-2; AzaINdole 1; TC-S 7001

    		 ROCK Cardiovascular Disease
    BAY-549 (Azaindole 1) is an orally active and ATP-competitive ROCK inhibitor with IC50s of 0.6 and 1.1 nM for human ROCK-1 and ROCK-2, respectively [1].
    BAY-549
  • HY-156796
    Akt/ROCK-IN-1

    		ADC Cytotoxin Neurological Disease Cancer
    Akt/ROCK-IN-1 (B12) is a dual inhibitor for Akt and ROCK, with the IC50s of 0.023 nM and 1.47 nM, respectively. Akt/ROCK-IN-1 has antitumor activity for neuroblastoma [1].
    Akt/<em>ROCK-IN-1</em>
  • HY-116238
    ROCK-IN-D2

    		ROCK Others
    ROCK-IN-D2 is a potent and selective ROCK inhibitor .
    <em>ROCK</em>-IN-D2
  • HY-13257G
    Thiazovivin

    		ROCK Cancer
    Thiazovivin (GMP) is Thiazovivin (HY-13257) produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture. Thiazovivin is a potent ROCK inhibitor .
    Thiazovivin
  • HY-100984
    HA-100
    1 Publications Verification

    		 PKA PKC Myosin ROCK Cancer
    HA-100 is a potent protein kinase inhibitor, with IC50s of 4 μM, 8 μM, 12 μM and 240 μM for cGMP-dependent protein kinase (PKG), cAMP-dependent protein kinase (PKA), protein kinase C (PKC) and MLC-kinase, respectively. HA-100 also used as a ROCK inhibitor .
    HA-100
  • HY-100984A
    HA-100 hydrochloride

    		PKA PKC Myosin ROCK Cancer
    HA-100 hydrochloride is a potent protein kinase inhibitor, with IC50s of 4 μM, 8 μM, 12 μM and 240 μM for cGMP-dependent protein kinase (PKG), cAMP-dependent protein kinase (PKA), protein kinase C (PKC) and MLC-kinase, respectively. HA-100 hydrochloride also used as a ROCK inhibitor .
    HA-100 hydrochloride
  • HY-12880
    HA-100 dihydrochloride

    		Myosin PKA PKC ROCK Cancer
    HA-100 dihydrochloride is a potent protein kinase inhibitor, with IC50s of 4 μM, 8 μM, 12 μM and 240 μM for cGMP-dependent protein kinase (PKG), cAMP-dependent protein kinase (PKA), protein kinase C (PKC) and MLC-kinase, respectively. HA-100 dihydrochloride also used as a ROCK inhibitor .
    HA-100 dihydrochloride
  • HY-N12466
    3′-O-Demethyl-4′-N-demethyl-4′-N-acetyl-4′-epi-staurosporine

    		PKC p38 MAPK ROCK Cancer
    3′-O-Demethyl-4′-N-demethyl-4′-N-acetyl-4′-epi-staurosporine (Compound 7) is an inhibitor of protein kinases, with IC50s of 0.092, 0.26, 0.77 μM for PKC-α, ROCK, ASK1. 3′-O-Demethyl-4′-N-demethyl-4′-N-acetyl-4′-epi-staurosporine shows potent cytotoxicity against PC-3 cancer cells with an IC50 value of 0.16 μM [1].
    3′-O-Demethyl-4′-N-demethyl-4′-N-acetyl-4′-epi-staurosporine

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