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Cat. No.: HY-116238

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ROCK-IN-D2

ROCK-IN-D2 is a potent and selective ROCK inhibitor.

For research use only. We do not sell to patients.

CAS No.: 1219721-78-4
Formula: C₂₂H₂₈N₆O
Molecular Weight:392.50

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

ROCK-IN-D2 Chemical Structure

CAS No.: 1219721-78-4

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

ROCK-IN-D2 is a potent and selective ROCK inhibitor^[1].

All ROCK Isoforms :

Chemical Information

CAS No. 1219721-78-4
Molecular Weight 392.50
Formula C₂₂H₂₈N₆O
SMILES

O=C(NCC1=CC=CC=C1)NC2=C(C=C(C=C2)C3=CNN=C3)N(C)CCN(C)C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Ding Mei, et al. Discovery of potent and selective urea-based ROCK inhibitors: Exploring the inhibitor’s potency and ROCK2/PKA selectivity by 3D-QSAR, molecular docking and molecular dynamics simulations.Bioorg Med Chem. 2015 May 15;23(10):2505-17. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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ROCK-IN-D2

All ROCK Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

ROCK-IN-D2 Related Classifications

HY-116238 Related Classifications