1. Signaling Pathways
  2. Cell Cycle/DNA Damage
    Cytoskeleton
    Stem Cell/Wnt
    TGF-beta/Smad
  3. ROCK
  4. ROCK Isoform

ROCK

 

ROCK Related Products (20):

Cat. No. Product Name Effect Purity
  • HY-13257
    Thiazovivin
    Inhibitor 99.94%
    Thiazovivin is a potent ROCK inhibitor, which can protect human embryonic stem cells.
  • HY-15727
    Afuresertib
    Inhibitor 99.54%
    Afuresertib (GSK2110183) is an orally bioavailable, selective, ATP-competitive and potent pan-Akt kinase inhibitor with Kis of 0.08/2/2.6 nM for Akt1/Akt2/Akt3, respectively.
  • HY-16563
    Narciclasine
    Activator 99.74%
    Narciclasine is a plant growth modulator.
  • HY-11000
    GSK429286A
    Inhibitor 98.15%
    GSK429286A is a selective inhibitor of ROCK1 with an IC50 value of 14 nM.
  • HY-12659
    LX7101
    Inhibitor 99.75%
    LX7101 is a potent inhibitor of LIMK and ROCK2 with IC50 values of 24, 1.6 and 10 nM for LIMK1, LIMK2 and ROCK2, respectively; also inhibits PKA with an IC50 less than 1 nM.
  • HY-121750
    CCG-222740
    Inhibitor 99.85%
    CCG-222740 is an orally active and selective Rho/myocardin-related transcription factor (MRTF) pathway inhibitor.
  • HY-10069
    Y-33075 dihydrochloride
    Inhibitor 98.75%
    Y-33075 dihydrochloride is a selective ROCK inhibitor with an IC50 of 3.6 nM.
  • HY-10067
    Y-33075
    Inhibitor 99.19%
    Y-33075 is a selective ROCK inhibitor derived from Y-27632, and is more potent than Y-27632, with an IC50 of 3.6 nM.
  • HY-15727A
    Afuresertib hydrochloride
    Inhibitor 99.03%
    Afuresertib hydrochloride (GSK 2110183 hydrochloride) is an orally bioavailable, selective, ATP-competitive and potent pan-Akt kinase inhibitor with Kis of 0.08/2/2.6 nM for Akt1/Akt2/Akt3 respectively.
  • HY-101244
    ZINC00881524
    Inhibitor 99.41%
    ZINC00881524 is a ROCK inhibitor.
  • HY-Q22471
    ROCK1-IN-1
    Inhibitor 98.86%
    ROCK1-IN-1 is a ROCK1 inhibitor with a Ki value of 540 nM.
  • HY-10583G
    Y-27632 dihydrochloride (GMP)
    Inhibitor
    Y-27632 dihydrochloride (GMP) is Y-27632 dihydrochloride (HY-10583) produced by using GMP guidelines.
  • HY-13257G
    Thiazovivin (GMP)
    Inhibitor
    Thiazovivin (GMP) is Thiazovivin (HY-13257) produced by using GMP guidelines.
  • HY-100035
    PT-262
    Inhibitor
    PT-262 is a potent ROCK inhibitor with an IC50 value of around 5 μM.
  • HY-100984A
    HA-100 hydrochloride
    Inhibitor
    HA-100 hydrochloride is a potent protein kinase inhibitor, with IC50s of 4 μM, 8 μM, 12 μM and 240 μM for cGMP-dependent protein kinase (PKG), cAMP-dependent protein kinase (PKA), protein kinase C (PKC) and MLC-kinase, respectively.
  • HY-139170
    CAY10746
    Inhibitor
    CAY10746 is a selective Rho kinase (ROCK) inhibitor.
  • HY-137436
    Cotosudil
    Inhibitor 99.05%
    Cotosudil is a ROCK kinase inhibitor, which can be used for glaucoma or ocular hypertension research.
  • HY-112362
    3-(4-Pyridyl)indole
    Inhibitor
    3-(4-Pyridyl)indole (Rockout) is a Rho-kinase (ROCK) inhibitor, with an IC50 of 25 μM.
  • HY-108519
    AS1892802
    Inhibitor
    AS1892802 is a potent, orally active, and highly selective inhibitor of ROCK.
  • HY-151189
    ROCK-IN-4
    Inhibitor
    ROCK-IN-4 is a potent ROCK inhibitor maintaining NO releasing ability.