ROCK2-IN-6 hydrochloride
Based on 1 Customer Validation
ROCK2-IN-6 hydrochloride (Comp A) is a selective ROCK2 inhibitor, can be used for ROCK mediated diseases, autoimmune diseases and inflammation research.
For research use only. We do not sell to patients.
- Purity: 99.69%
- CAS No.: 2762238-94-6
- Formula: C26H22ClF2N7O
- Molecular Weight:521.95
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Biological Activity
Chemical Information
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CAS No. 2762238-94-6
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Appearance Solid
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Molecular Weight 521.95
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Formula C26H22ClF2N7O
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Color Light yellow to yellow
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SMILES
O=C(N1CC(F)(C1)F)C2=CC3=C(N2C)C=C(C4=NC(NC5=CC=C(C6=CNN=C6)C=C5)=CC=N4)C=C3.[H]Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : 125 mg/mL (239.49 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (267 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.9159 mL | 9.5795 mL | 19.1589 mL | 47.8973 mL |
| 5 mM | 0.3832 mL | 1.9159 mL | 3.8318 mL | 9.5795 mL | |
| 10 mM | 0.1916 mL | 0.9579 mL | 1.9159 mL | 4.7897 mL | |
| 15 mM | 0.1277 mL | 0.6386 mL | 1.2773 mL | 3.1932 mL | |
| 20 mM | 0.0958 mL | 0.4790 mL | 0.9579 mL | 2.3949 mL | |
| 25 mM | 0.0766 mL | 0.3832 mL | 0.7664 mL | 1.9159 mL | |
| 30 mM | 0.0639 mL | 0.3193 mL | 0.6386 mL | 1.5966 mL | |
| 40 mM | 0.0479 mL | 0.2395 mL | 0.4790 mL | 1.1974 mL | |
| 50 mM | 0.0383 mL | 0.1916 mL | 0.3832 mL | 0.9579 mL | |
| 60 mM | 0.0319 mL | 0.1597 mL | 0.3193 mL | 0.7983 mL | |
| 80 mM | 0.0239 mL | 0.1197 mL | 0.2395 mL | 0.5987 mL | |
| 100 mM | 0.0192 mL | 0.0958 mL | 0.1916 mL | 0.4790 mL |